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Chemistry

D-Index
43
Citations
8353
World Ranking
17107
National Ranking
4210

Research.com Recognitions

  • 2015 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Amnon Kohen is affiliated with the University of Iowa in the United States. Their research primarily centers on biochemistry, genetics, and molecular biology, with a particular focus on enzyme structure and function as well as biochemical and molecular research. Their work spans several interdisciplinary subfields including molecular biology, materials chemistry, atomic and molecular physics, optics, oncology, and spectroscopy.

The scientist has published research covering topics such as protein structure and dynamics, mass spectrometry techniques and applications, force microscopy techniques and applications, mechanical and optical resonators, and molecular junctions and nanostructures.

Frequent publication venues for Kohen's work include:

  • Biochemistry
  • OPAL (Open@LaTrobe) (La Trobe University)
  • ACS Catalysis
  • Langmuir

Among recent papers authored or coauthored by Kohen are:

  • "Evolution of the Chemical Step in Enzyme Catalysis," 2021, ACS Catalysis
  • "Rigid Double-Stranded DNA Linkers for Single Molecule Enzyme-Drug Interaction Measurements Using Molecular Recognition Force Spectroscopy," 2020, Langmuir
  • "Evolution of Optimized Hydride Transfer Reaction and Overall Enzyme Turnover in Human Dihydrofolate Reductase," 2021, Biochemistry
  • "Caught in Action: X-ray Structure of Thymidylate Synthase with Noncovalent Intermediate Analog," 2021, Biochemistry
  • "The Effect of Protein Mass Modulation on Human Dihydrofolate Reductase," 2020, OPAL (Open@LaTrobe) (La Trobe University)

Kohen frequently collaborates with several coauthors, including:

  • Priyanka Singh
  • Christopher M. Cheatum
  • Janet Finer-Moore
  • Robert M. Stroud
  • Paul J. Sapienza

Kohen was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2015.

Best Publications

  • Enzyme dynamics and hydrogen tunnelling in a thermophilic alcohol dehydrogenase

    Amnon Kohen;Raffaele Cannio;Simonetta Bartolucci;Judith P. Klinman

  • Isotope Effects In Chemistry and Biology

    Amnon Kohen;Hans-Heinrich Limbach

  • Enzyme Catalysis: Beyond Classical Paradigms†

    Amnon Kohen;Judith P. Klinman

  • Hydrogen Tunneling Links Protein Dynamics to Enzyme Catalysis

    Judith P. Klinman;Amnon Kohen

  • Hydrogen tunneling in biology.

    Amnon Kohen;Judith P Klinman

  • Role of Dynamics in Enzyme Catalysis: Substantial versus Semantic Controversies

    Amnon Kohen

  • Tunneling and coupled motion in the Escherichia coli dihydrofolate reductase catalysis.

    R Steven Sikorski;Lin Wang;Kelli A Markham;P T Ravi Rajagopalan

  • Coordinated effects of distal mutations on environmentally coupled tunneling in dihydrofolate reductase

    Lin Wang;Nina M. Goodey;Stephen J. Benkovic;Amnon Kohen

  • Convex Arrhenius plots and their interpretation

    Donald G. Truhlar;Amnon Kohen

  • Arrhenius curves of hydrogen transfers: tunnel effects, isotope effects and effects of pre-equilibria.

    Hans Heinrich Limbach;Juan Miguel Lopez;Amnon Kohen

  • Effects of the donor-acceptor distance and dynamics on hydride tunneling in the dihydrofolate reductase catalyzed reaction.

    Vanja Stojković;Laura L. Perissinotti;Daniel Willmer;Stephen J. Benkovic

  • Effects of protein glycosylation on catalysis: changes in hydrogen tunneling and enthalpy of activation in the glucose oxidase reaction.

    Amnon Kohen;Thorlakur Jonsson;Judith P. Klinman

  • Kinetic Isotope Effects as Probes for Hydrogen Tunneling, Coupled Motion and Dynamics Contributions to Enzyme Catalysis:

    Amnon Kohen

  • An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene

    Eric M. Koehn;Todd Fleischmann;John A. Conrad;Bruce A. Palfey

  • Protein Flexibility Correlates with Degree of Hydrogen Tunneling in Thermophilic and Mesophilic Alcohol Dehydrogenases

    Amnon Kohen† and;Judith P. Klinman

  • Structural and Kinetic Studies of Formate Dehydrogenase from Candida boidinii.

    Qi Guo;Lokesh Gakhar;Kyle Wickersham;Kevin Francis

  • Effects of a distal mutation on active site chemistry.

    Lin Wang;Scott Tharp;Tzvia Selzer;Stephen J. Benkovic

  • Vibrationally Enhanced Hydrogen Tunneling in the Escherichia coli Thymidylate Synthase Catalyzed Reaction

    Nitish Agrawal;Baoyu Hong;Cornelia Mihai;Amnon Kohen

  • Line shape analysis of two-dimensional infrared spectra

    Qi Guo;Philip Pagano;Yun-Liang Li;Amnon Kohen

  • Elusive transition state of alcohol dehydrogenase unveiled

    Daniel Roston;Amnon Kohen

  • Characterizing the dynamics of functionally relevant complexes of formate dehydrogenase.

    Jigar N. Bandaria;Samrat Dutta;Michael W. Nydegger;William Rock

Frequent Co-Authors

Hans-Heinrich Limbach
Hans-Heinrich Limbach Freie Universität Berlin
Dan Thomas Major
Dan Thomas Major Bar-Ilan University
Vicent Moliner
Vicent Moliner Jaume I University
Judith P. Klinman
Judith P. Klinman University of California, Berkeley
Scott A. Lesley
Scott A. Lesley Genomics Institute of the Novartis Research Foundation
Stephen J. Benkovic
Stephen J. Benkovic Pennsylvania State University
Robert M. Stroud
Robert M. Stroud University of California, San Francisco
Frank Maley
Frank Maley New York State Department of Health
Po-Huang Liang
Po-Huang Liang Academia Sinica
Alán Aspuru-Guzik
Alán Aspuru-Guzik University of Toronto

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