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Chemistry

D-Index
91
Citations
28959
World Ranking
1973
National Ranking
721

Research.com Recognitions

  • 2012 - US President's National Medal of Science "For her discoveries of fundamental chemical and physical principles underlying enzyme catalysis and her leadership in the community of scientists.", Award presented by President Barack Obama at a ceremony in the East Room of the White House on November 20, 2014.
  • 2011 - Fellow of the American Chemical Society
  • 2007 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1994 - Member of the National Academy of Sciences
  • 1993 - Fellow of the American Academy of Arts and Sciences
  • 1988 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Judith P. Klinman is affiliated with the University of California, Berkeley in the United States. Their research spans multiple areas within biochemistry and chemistry, with 43 publications in Biochemistry, Genetics and Molecular Biology, and 15 in Chemistry. Their work delves into various subfields, including Molecular Biology, Inorganic Chemistry, Spectroscopy, Cellular and Molecular Neuroscience, and Materials Chemistry.

Their main research topics focus on:

  • Protein Structure and Dynamics
  • Photosynthetic Processes and Mechanisms
  • Metal-Catalyzed Oxygenation Mechanisms
  • Photoreceptor and Optogenetics Research
  • Microbial Metabolism and Enzyme Function
  • Mass Spectrometry Techniques and Applications
  • Enzyme Structure and Function

Judith P. Klinman has published frequently in several prominent journals and venues, including:

  • Biophysical Journal (8 publications)
  • Journal of the American Chemical Society (5 publications)
  • Proceedings of the National Academy of Sciences (2 publications)
  • ACS Central Science (2 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (2 publications)

Recent publications exemplify the scope and depth of their research:

  • "Biogenesis of the peptide-derived redox cofactor pyrroloquinoline quinone," 2020, Current Opinion in Chemical Biology
  • "Temporal and spatial resolution of distal protein motions that activate hydrogen tunneling in soybean lipoxygenase," 2023, Proceedings of the National Academy of Sciences
  • "Functional roles of enzyme dynamics in accelerating active site chemistry: Emerging techniques and changing concepts," 2022, Current Opinion in Structural Biology
  • "Hydrogen deuterium exchange defines catalytically linked regions of protein flexibility in the catechol O-methyltransferase reaction," 2020, Proceedings of the National Academy of Sciences
  • "Hydrogen-Deuterium Exchange within Adenosine Deaminase, a TIM Barrel Hydrolase, Identifies Networks for Thermal Activation of Catalysis," 2020, Journal of the American Chemical Society

The scientist has collaborated frequently with several researchers, including:

  • Anthony T. Iavarone (17 joint publications)
  • Shuaihua Gao (7 joint publications)
  • Adam R. Offenbacher (6 joint publications)
  • Priyanka Dubey (5 joint publications)
  • Emily J. Thompson (4 joint publications)

Judith P. Klinman has received multiple awards throughout their career, including:

  • US President's National Medal of Science in 2012, awarded by President Barack Obama for discoveries related to enzyme catalysis and leadership in the scientific community
  • Fellow of the American Chemical Society (2011)
  • Fellow of the American Association for the Advancement of Science (AAAS) (2007)
  • Member of the National Academy of Sciences (1994)
  • Fellow of the American Academy of Arts and Sciences (1993)
  • Fellow of John Simon Guggenheim Memorial Foundation (1988)

Best Publications

  • Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature

    Paul G. Arnison;Mervyn J. Bibb;Gabriele Bierbaum;Albert Alexander Bowers

  • Mechanisms Whereby Mononuclear Copper Proteins Functionalize Organic Substrates.

    Judith P. Klinman

  • A new redox cofactor in eukaryotic enzymes: 6-hydroxydopa at the active site of bovine serum amine oxidase

    Susan M. Janes;David Mu;David Wemmer;Alan J. Smith

  • Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.

    Glenn R. Masson;John E. Burke;Natalie G. Ahn;Ganesh S. Anand

  • Enzyme dynamics and hydrogen tunnelling in a thermophilic alcohol dehydrogenase

    Amnon Kohen;Raffaele Cannio;Simonetta Bartolucci;Judith P. Klinman

  • Hydrogen tunneling in enzyme reactions

    Yuan Cha;Christopher J. Murray;Judith P. Klinman

  • Temperature-dependent isotope effects in soybean lipoxygenase-1: correlating hydrogen tunneling with protein dynamics.

    Michael J. Knapp;Keith Rickert;Judith P. Klinman

  • A Crosslinked Cofactor in Lysyl Oxidase: Redox Function for Amino Acid Side Chains

    Sophie Xuefei Wang;Minae Mure;Katalin F. Medzihradszky;Alma L. Burlingame

  • Enzyme Catalysis: Beyond Classical Paradigms†

    Amnon Kohen;Judith P. Klinman

  • The copper-enzyme family of dopamine beta-monooxygenase and peptidylglycine alpha-hydroxylating monooxygenase: resolving the chemical pathway for substrate hydroxylation.

    Judith P. Klinman

  • Hydrogen Tunneling Links Protein Dynamics to Enzyme Catalysis

    Judith P. Klinman;Amnon Kohen

  • Hydrogen-Transfer Reactions

    James T. Hynes;Judith P. Klinman;Hans-Heinrich Limbach;Richard L. Schowen

  • Tunneling and Dynamics in Enzymatic Hydride Transfer

    Zachary D. Nagel;Judith P. Klinman

  • QUINOENZYMES IN BIOLOGY

    Judith P. Klinman;David Mu

  • A 21st century revisionist's view at a turning point in enzymology.

    Zachary D Nagel;Judith P Klinman

  • Environmentally coupled hydrogen tunneling. Linking catalysis to dynamics.

    Michael J. Knapp;Judith P. Klinman

  • Hydrogen tunneling in biology.

    Amnon Kohen;Judith P Klinman

  • Dopamine beta-hydroxylase of adrenal chromaffin granules: structure and function.

    Leslie C. Stewart;Judith P. Klinman

  • Catalytic mechanism of the topa quinone containing copper amine oxidases.

    Minae Mure;Stephen A. Mills;Judith P. Klinman

  • A link between protein structure and enzyme catalyzed hydrogen tunneling

    Brian J. Bahnson;Thomas D. Colby;Jodie K. Chin;Barry M. Goldstein

Frequent Co-Authors

Anthony T. Iavarone
Anthony T. Iavarone University of California, Berkeley
Amnon Kohen
Amnon Kohen University of Iowa
Natalie G. Ahn
Natalie G. Ahn University of Colorado Boulder
Alan Jay Smith
Alan Jay Smith University of California, Berkeley
Ninian J. Blackburn
Ninian J. Blackburn Oregon Health & Science University
R. David Britt
R. David Britt University of California, Davis
Joann Sanders-Loehr
Joann Sanders-Loehr Portland State University
Michael H. Glickman
Michael H. Glickman Technion – Israel Institute of Technology
Tom Alber
Tom Alber University of California, Berkeley
Benjamin J. Schwartz
Benjamin J. Schwartz University of California, Los Angeles

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