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Biology and Biochemistry

D-Index
90
Citations
26792
World Ranking
2457
National Ranking
1301

Overview

Betty A. Eipper is affiliated with the University of Connecticut Health Center in the United States. Their research primarily spans the fields of biochemistry, genetics, molecular biology, and medicine, with significant focus on molecular biology, cellular and molecular neuroscience, cardiology and cardiovascular medicine, physiology, and cell biology.

The main topics covered in their research include pancreatic function and diabetes, neuroscience and neuropharmacology, photosynthetic processes and mechanisms, atrial fibrillation management and outcomes, cardiac electrophysiology and arrhythmias, pituitary gland disorders and treatments, and cancer, hypoxia, and metabolism.

Among their recent publications are the following papers:

  • Peptidylglycine α-amidating monooxygenase is required for atrial secretory granule formation (2020), published in Proceedings of the National Academy of Sciences
  • Peptidylglycine α-amidating monooxygenase as a therapeutic target or biomarker for human diseases (2022), published in British Journal of Pharmacology
  • PAM haploinsufficiency does not accelerate the development of diet- and human IAPP-induced diabetes in mice (2020), published in Diabetologia
  • Germline loss-of-function PAM variants are enriched in subjects with pituitary hypersecretion (2023), published in Frontiers in Endocrinology
  • PERK-mediated expression of peptidylglycine α-amidating monooxygenase supports angiogenesis in glioblastoma (2020), published in Oncogenesis

Their work has been published multiple times in venues such as Zenodo (CERN European Organization for Nuclear Research), bioRxiv (Cold Spring Harbor Laboratory), Proceedings of the National Academy of Sciences, Diabetologia, and British Journal of Pharmacology.

Betty A. Eipper has frequently collaborated with several researchers throughout their career. Notable co-authors include Richard E. Mains, Giampaolo Trivellin, Adrian Daly, Laura C. Hernández-Ramírez, and Elisa Araldi.

Best Publications

  • Common precursor to corticotropins and endorphins

    Richard E. Mains;Betty A. Eipper;Nicholas Ling

  • Structure and Biosynthesis of Pro-Adrenocorticotropin/Endorphin and Related Peptides*

    Betty A. Eipper;Richard E. Mains

  • The Biosynthesis of Neuropeptides: Peptide alpha-Amidation

    B A Eipper;D A Stoffers;R E Mains

  • Rapid induction of dendritic spine morphogenesis by trans-synaptic ephrinB-EphB receptor activation of the Rho-GEF kalirin.

    Peter Penzes;Alexander Beeser;Jonathan Chernoff;Martin R. Schiller

  • Identification in pituitary tissue of a peptide alpha-amidation activity that acts on glycine-extended peptides and requires molecular oxygen, copper, and ascorbic acid

    Betty A. Eipper;Richard E. Mains;Christopher C. Glembotski

  • New insights into copper monooxygenases and peptide amidation: structure, mechanism and function.

    S. T. Prigge;R. E. Mains;B. A. Eipper;L. M. Amzel

  • The neuronal Rho-GEF Kalirin-7 interacts with PDZ domain-containing proteins and regulates dendritic morphogenesis.

    Peter Penzes;Richard C. Johnson;Rita Sattler;Xiaoqun Zhang

  • Dioxygen Binds End-On to Mononuclear Copper in a Precatalytic Enzyme Complex

    Sean T. Prigge;Betty A. Eipper;Richard E. Mains;L. Mario Amzel

  • Amidation of Bioactive Peptides: The Structure of Peptidylglycine α-Hydroxylating Monooxygenase

    Sean T. Prigge;Aparna S. Kolhekar;Betty A. Eipper;Richard E. Mains

  • Neuropeptide Y functions as a neuroproliferative factor

    D. E. Hansel;B. A. Eipper;B. A. Eipper;G. V. Ronnett

  • Synthesis and secretion of corticotropins, melanotropins, and endorphins by rat intermediate pituitary cells.

    R E Mains;B A Eipper

  • Peptide alpha-amidation.

    B A Eipper;R E Mains

  • Peptidylglycine alpha-amidating monooxygenase: a multifunctional protein with catalytic, processing, and routing domains.

    Eipper Ba;Milgram Sl;Husten Ej;Yun Hy

  • Biosynthesis of adrenocorticotropic hormone in mouse pituitary tumor cells.

    R E Mains;B A Eipper

  • Rat brain microtubule protein: purification and determination of covalently bound phosphate and carbohydrate.

    Betty A. Eipper

  • Existence of a common precursor to ACTH and endorphin in the anterior and intermediate lobes of the rat pituaitary

    Betty A. Eipper;Richard E. Mains

  • Prohormone-Converting Enzymes: Regulation and Evaluation of Function Using Antisense RNA

    Brian T. Bloomquist;Betty A. Eipper;Richard E. Mains

  • Analysis of the common precursor to corticotropin and endorphin.

    B A Eipper;R E Mains

  • Strategies for the biosynthesis of bioactive peptides

    Richard E. Mains;Betty A. Eipper;Christopher C. Glembotski;Robert M. Dores

  • Purification and characterization of peptidylglycine alpha-amidating monooxygenase from bovine neurointermediate pituitary.

    A S Murthy;R E Mains;B A Eipper

Frequent Co-Authors

Richard E. Mains
Richard E. Mains University of Connecticut Health Center
Henry T. Keutmann
Henry T. Keutmann Harvard University
L. Mario Amzel
L. Mario Amzel Johns Hopkins University School of Medicine
Stephen M. King
Stephen M. King University of Connecticut Health Center
Gary S. Wand
Gary S. Wand Johns Hopkins University School of Medicine
Peter Penzes
Peter Penzes Northwestern University
Christopher C. Glembotski
Christopher C. Glembotski University of Arizona
John E. Pintar
John E. Pintar Rutgers, The State University of New Jersey
Aaron G. Maule
Aaron G. Maule Queen's University Belfast
William C. Wetsel
William C. Wetsel Duke University

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