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D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
10457
World Ranking
12744
National Ranking
5432

Vivian Hook publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Vivian Hook sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 210 publications — 54th percentile

54% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Vivian Hook D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Vivian Hook sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 59 D-Index — 38th percentile

38% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Vivian Hook is affiliated with the University of California, San Diego in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with significant work in the molecular biology, physiology, cellular and molecular neuroscience, cancer research, and cell biology subfields.

The scientist has contributed extensively to the study of Alzheimer's disease research and treatments, protease and inhibitor mechanisms, mitochondrial function and pathology, S100 proteins and annexins, neuroscience and neuropharmacology research, antimicrobial peptides and activities, and peptidase inhibition and analysis.

Among their recent publications are:

  • Cathepsin B in neurodegeneration of Alzheimer's disease, traumatic brain injury, and related brain disorders (2020) published in Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  • A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells (2021) published in ACS Chemical Biology
  • Cathepsin B Gene Knockout Improves Behavioral Deficits and Reduces Pathology in Models of Neurologic Disorders (2022) published in Pharmacological Reviews
  • Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L (2021) published in Journal of Medicinal Chemistry
  • Multi-omics of human plasma reveals molecular features of dysregulated inflammation and accelerated aging in schizophrenia (2021) published in Molecular Psychiatry

Frequent coauthors of Vivian Hook include Sonia Podvin, Anthony J. O'Donoghue, Michael C. Yoon, Charles Mosier, and William H. Gerwick.

Key publication venues where their work frequently appears are:

  • ACS Chemical Neuroscience
  • ACS Chemical Biology
  • Biochemistry
  • Journal of Huntington's Disease
  • ACS Omega

Best Publications

  • The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.

    Francine E. Garrett-Bakelman;Francine E. Garrett-Bakelman;Manjula Darshi;Stefan J. Green;Ruben C. Gur

  • Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease

    E Hermel;E Hermel;J Gafni;S S Propp;B R Leavitt

  • Proteases for Processing Proneuropeptides into Peptide Neurotransmitters and Hormones

    Vivian Hook;Lydiane Funkelstein;Douglas Lu;Steven Bark

  • Inhibitors of Cathepsin B Improve Memory and Reduce β-Amyloid in Transgenic Alzheimer Disease Mice Expressing the Wild-type, but Not the Swedish Mutant, β-Secretase Site of the Amyloid Precursor Protein

    Vivian Y. H. Hook;Mark Kindy;Gregory Hook

  • Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter

    Sukkid Yasothornsrikul;Doron Greenbaum;Katalin F. Medzihradszky;Thomas Toneff

  • Inhibition of cathepsin B reduces β-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate β-secretase of Alzheimer's disease

    Vivian Hook;Thomas Toneff;Matthew Bogyo;Doron Greenbaum

  • Tissue-Specific Proteolysis of Huntingtin (htt) in Human Brain: Evidence of Enhanced Levels of N- and C-Terminal htt Fragments in Huntington's Disease Striatum

    Liane M. Mende-Mueller;Thomas Toneff;Thomas Toneff;Shin-Rong Hwang;Shin-Rong Hwang;Marie-Francoise Chesselet

  • A carboxypeptidase processing enzyme for enkephalin precursors

    Vivian Y. H. Hook;Lee E. Eiden;Michael J. Brownstein

  • Carboxypeptidase B-like converting enzyme activity in secretory granules of rat pituitary

    V Y Hook;Y P Loh

  • Somatostatin inhibits multireceptor stimulation of cyclic AMP formation and corticotropin secretion in mouse pituitary tumor cells.

    Seymour Heisler;Terry D. Reisine;Vivian Y. H. Hook;Julius Axelrod

  • Proteases and the emerging role of protease inhibitors in prohormone processing.

    V. Y. H. Hook;A. V. Azaryan;Shin-Rong Hwang;N. Tezapsidis

  • Corticotropin releasing factor stimulates adrenocorticotropin and β-endorphin release from AtT-20 mouse pituitary tumor cells

    Vivian Y.H. Hook;Seymour Heisler;Steven L. Sabol;Julius Axelrod

  • The cysteine protease inhibitor, E64d, reduces brain amyloid-β and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, β-secretase activity.

    Gregory Hook;Vivian Hook;Mark Kindy;Mark Kindy

  • Genetic cathepsin B deficiency reduces β-amyloid in transgenic mice expressing human wild-type amyloid precursor protein

    Vivian Y.H. Hook;Mark Kindy;Thomas Reinheckel;Christoph Peters

  • Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons.

    Vivian Hook;Vivian Hook;Kristen J. Brennand;Yongsung Kim;Thomas Toneff

  • Cathepsin B in Neurodegeneration of Alzheimer’s Disease, Traumatic Brain Injury, and Related Brain Disorders

    Vivian Hook;Vivian Hook;Michael Yoon;Charles Mosier;Gen Ito

  • Cathepsin B is a New Drug Target for Traumatic Brain injury Therapeutics: evidence for e64d as a Promising Lead Drug Candidate

    Gregory Hook;J. Steven Jacobsen;Kenneth Grabstein;Mark Kindy;Mark Kindy

  • Alternative pathways for production of beta-amyloid peptides of Alzheimer's disease.

    Vivian Hook;Israel Schechter;Hans-Ulrich Demuth;Gregory Hook

  • Expansion of the mycobacterial “PUPylome”

    Jeramie Watrous;Kristin Burns;Wei-Ting Liu;Anand Patel

  • MAJOR ROLE OF CATHEPSIN L FOR PRODUCING THE PEPTIDE HORMONES ACTH, β-ENDORPHIN, AND α-MSH, ILLUSTRATED BY PROTEASE GENE KNOCKOUT AND EXPRESSION

    Lydiane Funkelstein;Thomas Toneff;Charles Mosier;Shin-Rong Hwang

Frequent Co-Authors

Mark S. Kindy
Mark S. Kindy University of South Florida
Daniel T. O'Connor
Daniel T. O'Connor University of California, San Diego
Sushil K. Mahata
Sushil K. Mahata University of California, San Diego
Jill L. Wegrzyn
Jill L. Wegrzyn University of Connecticut
Michael G. Ziegler
Michael G. Ziegler University of California, San Diego
Christoph Peters
Christoph Peters University of Freiburg
Thomas Reinheckel
Thomas Reinheckel University of Freiburg
William H. Gerwick
William H. Gerwick University of California, San Diego
William S. Lane
William S. Lane Harvard University
Julius Axelrod
Julius Axelrod National Institutes of Health

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