Iris Lindberg

Research.com Recognitions

• 2018 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects

  Xiaorong Zhu;An Zhou;Arunangsu Dey;Christina Norrbom

  413
  Citations

• The crystal structure of the proprotein processing proteinase furin explains its stringent specificity.

  Stefan Henrich;Angus Cameron;Angus Cameron;Gleb P Bourenkov;Reiner Kiefersauer

  403
  Citations

• Polyarginines Are Potent Furin Inhibitors

  Angus Cameron;Jon Appel;Richard A. Houghten;Iris Lindberg

  273
  Citations

• The neuroendocrine protein 7B2 is required for peptide hormone processing in vivo and provides a novel mechanism for pituitary Cushing's disease.

  Christoph H Westphal;Laurent Muller;An Zhou;Xiaorong Zhu

  216
  Citations

• Purification and characterization of the prohormone convertase PC1(PC3).

  Yi Zhou;I. Lindberg

  208
  Citations

• Prodynorphin Processing by Proprotein Convertase 2 CLEAVAGE AT SINGLE BASIC RESIDUES AND ENHANCED PROCESSING IN THE PRESENCE OF CARBOXYPEPTIDASE ACTIVITY

  Robert Day;Claude Lazure;Ajoy Basak;Alain Boudreault

  194
  Citations

• Proprotein convertase models based on the crystal structures of furin and kexin: explanation of their specificity.

  Stefan Henrich;Iris Lindberg;Wolfram Bode;Manuel E. Than

  185
  Citations

• 7B2 facilitates the maturation of proPC2 in neuroendocrine cells and is required for the expression of enzymatic activity.

  Xiaorong Zhu;Iris Lindberg

  177
  Citations

• The neuroendocrine polypeptide 7B2 is an endogenous inhibitor of prohormone convertase PC2

  Gerard J. M. Martens;Joanna A. M. Braks;Douglas W. Eib;Yi Zhou

  176
  Citations

• Differential processing of proenkephalin by prohormone convertases 1(3) and 2 and furin.

  M B Breslin;I Lindberg;S Benjannet;J P Mathis

  173
  Citations

• The cell biology of the prohormone convertases PC1 and PC2.

  Laurent Muller;I Lindberg

  159
  Citations

• Congenital proprotein convertase 1/3 deficiency causes malabsorptive diarrhea and other endocrinopathies in a pediatric cohort

  Martín G. Martín;Iris Lindberg;R. Sergio Solorzano–Vargas;Jiafang Wang

  153
  Citations

• Biosynthesis of the prohormone convertase mPC1 in AtT-20 cells.

  Osvaldo Vindrola;Iris Lindberg

  151
  Citations

• Inhibition of furin by polyarginine-containing peptides: nanomolar inhibition by nona-D-arginine

  Magdalena M. Kacprzak;Juan R. Peinado;Manuel E. Than;Jon Appel

  140
  Citations

• Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics.

  Gero L. Becker;Frank Sielaff;Manuel E. Than;Iris Lindberg

  121
  Citations

• Specificity of Prohormone Convertase 2 on Proenkephalin and Proenkephalin-related Substrates

  Karla Johanning;Maria A. Juliano;Luiz Juliano;Claude Lazure

  120
  Citations

• The Furin Inhibitor Hexa-d-Arginine Blocks the Activation of Pseudomonas aeruginosa Exotoxin A In Vivo

  Miroslav S. Sarac;Angus Cameron;Iris Lindberg

  119
  Citations

• Highly potent inhibitors of proprotein convertase furin as potential drugs for treatment of infectious diseases

  Gero L. Becker;Yinghui Lu;Kornelia Hardes;Boris Strehlow

  118
  Citations

• Mechanism of the Facilitation of PC2 Maturation by 7B2: Involvement in ProPC2 Transport and Activation but Not Folding

  Laurent Muller;Xiaorong Zhu;Iris Lindberg

  117
  Citations

• Internal cleavage of the inhibitory 7B2 carboxyl-terminal peptide by PC2: A potential mechanism for its inactivation

  X Zhu;Y Rouille;N S Lamango;D F Steiner

  115
  Citations