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Microbiology

D-Index
74
Citations
16807
World Ranking
1598
National Ranking
115

Overview

Wolfgang Garten is affiliated with Philipp University of Marburg in Germany. Their research primarily focuses on the fields of Medicine and Immunology and Microbiology, with particular attention to Infectious Diseases, Immunology, and Public Health, Environmental and Occupational Health.

The main topics covered in their work include:

  • SARS-CoV-2 and COVID-19 Research
  • Interferon and immune responses
  • COVID-19 Clinical Research Studies
  • Mosquito-borne diseases and control

Wolfgang Garten has contributed to several notable publications. Among the recent papers are:

  • "TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells" (2020), published in Life Science Alliance
  • "TMPRSS2 and furin are both essential for proteolytic activation and spread of SARS-CoV-2 in human airway epithelial cells and provide promising drug targets" (2020), published in bioRxiv (Cold Spring Harbor Laboratory)

Their frequent co-authors include:

  • Dorothea Bestle
  • Miriam Ruth Heindl
  • Hannah Limburg
  • Thuy Van Lam van
  • Oliver Pilgram

Wolfgang Garten's publications have appeared mainly in the journals Life Science Alliance and bioRxiv (Cold Spring Harbor Laboratory).

Best Publications

  • Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease.

    A. Stieneke-Gröber;M. Vey;H. Angliker;E. Shaw

  • TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells.

    Dorothea Bestle;Miriam Ruth Heindl;Hannah Limburg;Thuy van Lam van

  • Host cell proteases controlling virus pathogenicity

    Hans-Dieter Klenk;Wolfgang Garten

  • Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gpl60

    Unknown

  • Proteolytic Activation of Influenza Viruses by Serine Proteases TMPRSS2 and HAT from Human Airway Epithelium

    Eva Böttcher;Tatyana Matrosovich;Michaela Beyerle;Hans-Dieter Klenk

  • New low-viscosity overlay medium for viral plaque assays

    Mikhail Matrosovich;Tatyana Matrosovich;Wolfgang Garten;Hans Dieter Klenk

  • Proteolytic cleavage of influenza virus hemagglutinins: primary structure of the connecting peptide between HA1 and HA2 determines proteolytic cleavability and pathogenicity of Avian influenza viruses.

    F.X. Bosch;W. Garten;H.-D. Klenk;R. Rott

  • The Lassa virus glycoprotein precursor GP-C is proteolytically processed by subtilase SKI-1/S1P.

    Oliver Lenz;Jan ter Meulen;Hans-Dieter Klenk;Nabil G. Seidah

  • Regulation of the α -secretase ADAM10 by its prodomain and proprotein convertases

    Andreas Anders;Sandra Gilbert;Wolfgang Garten;Rolf Postina

  • Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furin.

    W. Schäfer;A. Stroh;S. Berghöfer;J. Seiler

  • Lassa Virus Z Protein Is a Matrix Protein Sufficient for the Release of Virus-Like Particles

    Thomas Strecker;Robert Eichler;Jan ter Meulen;Winfried Weissenhorn

  • Major proteins of the Escherichia coli outer cell envelope membrane. Interaction of protein II with lipopolysaccharide.

    Margarete Schweizer;Ingrid Hindennach;Wolfgang Garten;Ulf Henning

  • Endoproteolytic Processing of the Lymphocytic Choriomeningitis Virus Glycoprotein by the Subtilase SKI-1/S1P

    Winfried R. Beyer;Dennis Pöpplau;Wolfgang Garten;Dorothee von Laer

  • Cleavage of Influenza Virus Hemagglutinin by Airway Proteases TMPRSS2 and HAT Differs in Subcellular Localization and Susceptibility to Protease Inhibitors

    Eva Böttcher-Friebertshäuser;Catharina Freuer;Frank Sielaff;Sarah Schmidt

  • Proteolytic activation of the influenza virus hemagglutinin: The structure of the cleavage site and the enzymes involved in cleavage

    Wolfgang Garten;Franz X. Bosch;Dietmar Linder;Rudolf Rott

  • Processing of viral glycoproteins by the subtilisin-like endoprotease furin and its inhibition by specific peptidylchloroalkylketones

    W. Garten;S. Hallenberger;D. Ortmann;W. Schäfer

  • Ectodomain shedding of the glycoprotein GP of Ebola virus

    Olga Dolnik;Olga Dolnik;Valentina Volchkova;Wolfgang Garten;Caroline Carbonnelle

  • Hemagglutinin activation of pathogenic avian influenza viruses of serotype H7 requires the protease recognition motif R-X-K/R-R.

    Martin Vey;Michaela Orlich;Sabine Adler;Hans-Dieter Klenk

  • Maturation of the trans-Golgi network protease furin: compartmentalization of propeptide removal, substrate cleavage, and COOH-terminal truncation.

    M Vey;W Schäfer;S Berghöfer;H D Klenk

  • Identification of Lassa virus glycoprotein signal peptide as a trans-acting maturation factor.

    Robert Eichler;Oliver Lenz;Thomas Strecker;Markus Eickmann

  • Activation of influenza viruses by proteases from host cells and bacteria in the human airway epithelium

    Eva Böttcher-Friebertshäuser;Hans-Dieter Klenk;Wolfgang Garten

  • Role of conserved glycosylation sites in maturation and transport of influenza A virus hemagglutinin.

    P C Roberts;W Garten;H D Klenk

Frequent Co-Authors

Hans-Dieter Klenk
Hans-Dieter Klenk Philipp University of Marburg
Markus Eickmann
Markus Eickmann Philipp University of Marburg
Mikhail Matrosovich
Mikhail Matrosovich Philipp University of Marburg
Rudolf Rott
Rudolf Rott University of Giessen
Ute Ströher
Ute Ströher Centers for Disease Control and Prevention
Stephan Becker
Stephan Becker Philipp University of Marburg
Jürgen A. Richt
Jürgen A. Richt Kansas State University
Iris Lindberg
Iris Lindberg University of Maryland, Baltimore
Winfried Weissenhorn
Winfried Weissenhorn Grenoble Alpes University
Larissa Kolesnikova
Larissa Kolesnikova Philipp University of Marburg

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