2023 - Research.com Microbiology in Germany Leader Award
The scientist’s investigation covers issues in Virology, Coronavirus, Virus, Proteases and Protease. In his study, Molecular biology is strongly linked to Cell culture, which falls under the umbrella field of Virology. The various areas that Stefan Pöhlmann examines in his Coronavirus study include Pandemic, Betacoronavirus and Severe acute respiratory syndrome coronavirus 2.
His work on Tissue tropism as part of general Virus study is frequently linked to Coronaviridae, bridging the gap between disciplines. His Proteases research incorporates elements of Viral entry and Transmembrane protein. His research integrates issues of Cathepsin and Orthomyxoviridae in his study of Protease.
Stefan Pöhlmann focuses on Virology, Virus, Viral entry, Coronavirus and Cell culture. His studies in Virology integrate themes in fields like Proteases, DC-SIGN and Antibody. His Proteases research is multidisciplinary, incorporating elements of Serine protease, Protease, Cathepsin and Transmembrane protein.
His study in the fields of Neutralization and Neutralizing antibody under the domain of Antibody overlaps with other disciplines such as Severe acute respiratory syndrome coronavirus 2. The concepts of his Viral entry study are interwoven with issues in Infectivity, Sphingosine, Immune system and Cell biology. His Coronavirus study frequently draws connections between adjacent fields such as Middle East respiratory syndrome.
His primary scientific interests are in Virology, Virus, Coronavirus, Severe acute respiratory syndrome coronavirus 2 and Antibody. His Virology study combines topics from a wide range of disciplines, such as Cell culture, Protease and Immune system. His Virus research incorporates themes from Seroprevalence, In vivo and Cell biology.
His Coronavirus research is multidisciplinary, relying on both Middle East respiratory syndrome and Betacoronavirus. His research investigates the link between Antibody and topics such as Vaccination that cross with problems in Blockade and Recombinant DNA. His study in Viral entry is interdisciplinary in nature, drawing from both Ex vivo, Proteases, Sphingosine, Sphingolipid and Ebola virus.
His primary areas of investigation include Virology, Coronavirus, Antibody, Neutralization and Severe acute respiratory syndrome coronavirus 2. His Virology study integrates concerns from other disciplines, such as Cell culture and Receptor. His work carried out in the field of Receptor brings together such families of science as Serine protease and Priming.
His study brings together the fields of Middle East respiratory syndrome and Coronavirus. His studies deal with areas such as Blockade, Recombinant DNA and Vaccination as well as Antibody. His Neutralization study incorporates themes from Cell and Vesicular stomatitis virus.
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SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
Markus Hoffmann;Hannah Kleine-Weber;Simon Schroeder;Nadine Krüger.
A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells.
Markus Hoffmann;Hannah Kleine-Weber;Stefan Pöhlmann.
Molecular Cell (2020)
Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response
Ilona Glowacka;Stephanie Bertram;Marcel A. Müller;Paul Allen.
Journal of Virology (2011)
Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry
Heike Hofmann;Krzysztof Pyrc;Lia van der Hoek;Martina Geier.
Proceedings of the National Academy of Sciences of the United States of America (2005)
TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein.
Adeline Heurich;Heike Hofmann-Winkler;Stefanie Gierer;Thomas Liepold.
Journal of Virology (2014)
Diversity of receptors binding HIV on dendritic cell subsets
Stuart G. Turville;Paul U. Cameron;Amanda Handley;George Lin.
Nature Immunology (2002)
The novel coronavirus 2019 (2019-nCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells
Hoffmann M;Kleine-Weber H;Krüger N;Müller M.
Protease inhibitors targeting coronavirus and filovirus entry
Yanchen Zhou;Punitha Vedantham;Kai Lu;Juliet Agudelo.
Antiviral Research (2015)
Hepatitis C Virus Glycoproteins Interact with DC-SIGN and DC-SIGNR
Stefan Pöhlmann;Jie Zhang;Frédéric Baribaud;Zhiwei Chen.
Journal of Virology (2003)
Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics
Jacqueline D. Reeves;Stephen A. Gallo;Navid Ahmad;John L. Miamidian.
Proceedings of the National Academy of Sciences of the United States of America (2002)
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