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Genetics

D-Index
56
Citations
12777
World Ranking
3487
National Ranking
1513

Overview

Peter C. Scacheri is affiliated with Case Western Reserve University in the United States. Their research focuses primarily on Biochemistry, Genetics, and Molecular Biology, contributing extensively to the field through a significant number of publications. Their work spans several subfields, including Molecular Biology, Genetics, Cancer Research, Immunology, and Pharmacology.

They have contributed to the understanding of genomics and chromatin dynamics, epigenetics and DNA methylation, immune cells in cancer, RNA modifications and cancer, cancer genomics and diagnostics, microRNA in disease regulation, and genetic associations and epidemiology. These topics highlight the depth and interdisciplinary approach of their research activity.

Their publication record includes numerous papers in respected venues. Notable recent papers include:

  • Robust Hi-C Maps of Enhancer-Promoter Interactions Reveal the Function of Non-coding Genome in Neural Development and Diseases, 2020, Molecular Cell
  • Cell Type-Specific Intralocus Interactions Reveal Oligodendrocyte Mechanisms in MS, 2020, Cell
  • CHD7 promotes neural progenitor differentiation in embryonic stem cells via altered chromatin accessibility and nascent gene expression, 2020, Scientific Reports
  • Distinct Cell Adhesion Signature Defines Glioblastoma Myeloid-Derived Suppressor Cell Subsets, 2022, Cancer Research
  • Chromatin Mechanisms Driving Cancer, 2021, Cold Spring Harbor Perspectives in Biology

The frequent publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Cell
  • Cancer Epidemiology Biomarkers & Prevention
  • Neuro-Oncology

Peter C. Scacheri has collaborated extensively, with frequent co-authors including Cynthia F. Bartels, Katreya Lovrenert, Olivia Corradin, Víctor Moreno, and Ulrike Peters. These collaborations demonstrate a network of research partnerships across related fields.

Best Publications

  • Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

    Peter C. Scacheri;Orit Rozenblatt-Rosen;Natasha J. Caplen;Tyra G. Wolfsberg

  • CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing.

    Feng Tie;Rakhee Banerjee;Carl A. Stratton;Jayashree Prasad-Sinha

  • Epigenetic signatures distinguish multiple classes of enhancers with distinct cellular functions

    Gabriel E. Zentner;Paul J. Tesar;Peter C. Scacheri

  • A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors

    Judy S. Crabtree;Peter Christopher Scacheri;Jerrold M. Ward;Lisa Garrett-Beal

  • Discovery of common and rare genetic risk variants for colorectal cancer

    Jeroen R. Huyghe;Stephanie A. Bien;Tabitha A. Harrison;Hyun Min Kang

  • Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits.

    Olivia Corradin;Alina Saiakhova;Batool Akhtar-Zaidi;Lois Myeroff

  • Epigenomic enhancer profiling defines a signature of colon cancer

    Batool Akhtar-Zaidi;Batool Akhtar-Zaidi;Richard Cowper-Sal·lari;Olivia Corradin;Alina Saiakhova

  • Molecular and phenotypic aspects of CHD7 mutation in CHARGE syndrome.

    Gabriel E. Zentner;Wanda S. Layman;Donna M. Martin;Peter C. Scacheri

  • DNase-chip: A high-resolution method to identify DNase I hypersensitive sites using tiled microarrays

    Gregory E Crawford;Sean Davis;Peter C Scacheri;Gabriel Renaud

  • CHD7 Targets Active Gene Enhancer Elements to Modulate ES Cell-Specific Gene Expression

    Michael P. Schnetz;Lusy Handoko;Batool Akhtar-Zaidi;Cynthia F. Bartels

  • Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns

    Michael P. Schnetz;Cynthia F. Bartels;Kuntal Shastri;Dheepa Balasubramanian

  • Functional Enhancers Shape Extrachromosomal Oncogene Amplifications

    Andrew R. Morton;Nergiz Dogan-Artun;Zachary J. Faber;Graham MacLeod

  • Of Mice and MEN1: Insulinomas in a Conditional Mouse Knockout

    Judy S. Crabtree;Peter C. Scacheri;Jerrold M. Ward;Sara R. McNally

  • Enhancer variants: evaluating functions in common disease

    Olivia Corradin;Peter Christopher Scacheri

  • Genome-Wide Analysis of Menin Binding Provides Insights into MEN1 Tumorigenesis

    Peter C Scacheri;Sean Davis;Duncan T Odom;Gregory E Crawford

  • ZNF143 provides sequence specificity to secure chromatin interactions at gene promoters.

    Swneke D. Bailey;Swneke D. Bailey;Xiaoyang Zhang;Xiaoyang Zhang;Kinjal Desai;Malika Aid

  • Molecular Pathology of the MEN1 Gene

    Sunita K. Agarwal;A. Lee Burns;Karen E. Sukhodolets;Patricia A. Kennedy

  • Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling

    Stephen C. Mack;Kristian W. Pajtler;Kristian W. Pajtler;Lukas Chavez;Lukas Chavez;Konstantin Okonechnikov

  • Transcription elongation factors represent in vivo cancer dependencies in glioblastoma

    Tyler E. Miller;Tyler E. Miller;Brian B. Liau;Brian B. Liau;Lisa C. Wallace;Andrew R. Morton;Andrew R. Morton

  • Discovery of common and rare genetic risk variants for colorectal cancer

    Jeroen R. Huyghe;Stephanie A. Bien;Tabitha A. Harrison;Hyun Min Kang

Frequent Co-Authors

Sanford D. Markowitz
Sanford D. Markowitz Case Western Reserve University
Jeremy N. Rich
Jeremy N. Rich University of Pittsburgh
Francis S. Collins
Francis S. Collins National Institutes of Health
Alicja Wolk
Alicja Wolk Karolinska Institute
Daniel D. Buchanan
Daniel D. Buchanan University of Melbourne
Allen M. Spiegel
Allen M. Spiegel Albert Einstein College of Medicine
Kenneth Offit
Kenneth Offit Memorial Sloan Kettering Cancer Center
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Andrew T. Chan
Andrew T. Chan Harvard University
Stephen B. Gruber
Stephen B. Gruber City Of Hope National Medical Center

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