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Medicine

D-Index
99
Citations
46813
World Ranking
8457
National Ranking
480

Overview

Hiltrud Brauch is affiliated with the German Cancer Research Center in Germany. Their research is primarily focused on the fields of biochemistry, genetics, and molecular biology, with notable contributions in genetics, molecular biology, cancer research, oncology, and pharmacology.

The scientist's work spans several main topics, including:

  • BRCA gene mutations in cancer
  • Genetic Associations and Epidemiology
  • Estrogen and related hormone effects
  • Breast Cancer Treatment Studies
  • Pharmacogenetics and Drug Metabolism
  • Epigenetics and DNA Methylation
  • Nutrition, Genetics, and Disease

Hiltrud Brauch has contributed to multiple recent papers, with a focus on breast cancer genetics and risk assessment. Some key publications include:

  • "Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women," 2021, New England Journal of Medicine
  • "Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses," 2020, Nature Genetics
  • "Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes," 2020, Nature Genetics
  • "Combined Associations of a Polygenic Risk Score and Classical Risk Factors With Breast Cancer Risk," 2020, JNCI Journal of the National Cancer Institute
  • "Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk," 2020, The American Journal of Human Genetics

Frequent publication venues for their work include UNC Libraries, Nature Communications, Breast Cancer Research, Clinical Pharmacology & Therapeutics, and bioRxiv (Cold Spring Harbor Laboratory).

Hiltrud Brauch collaborates regularly with several coauthors, notably:

  • Manjeet K. Bolla
  • Stig E. Bojesen
  • Joe Dennis
  • Kamila Czene
  • Peter A. Fasching

Best Publications

  • Genome-wide association study identifies novel breast cancer susceptibility loci

    Douglas F. Easton;Karen A. Pooley;Alison M. Dunning;Paul D. P. Pharoah

  • Mutations of the VHL tumour suppressor gene in renal carcinoma

    J.R. Gnarra;K. Tory;Y. Weng;L. Schmidt

  • Germline and Somatic Mutations in the Tyrosine Kinase Domain of the MET Proto-Oncogene in Papillary Renal Carcinomas

    L. Schmidt;F.-M. Duh;F. Chen;T. Kishida

  • Association analysis identifies 65 new breast cancer risk loci

    Kyriaki Michailidou;Kyriaki Michailidou;Sara Lindström;Sara Lindström;Joe Dennis;Jonathan Beesley

  • Large-scale genotyping identifies 41 new loci associated with breast cancer risk

    Kyriaki Michailidou;Per Hall;Anna Gonzalez-Neira;Maya Ghoussaini

  • RAD51B in Familial Breast Cancer

    Liisa M. Pelttari;Sofia Khan;Mikko Vuorela;Johanna I. Kiiski

  • Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

    Nasim Mavaddat;Kyriaki Michailidou;Kyriaki Michailidou;Joe Dennis;Michael Lush

  • Associations of Breast Cancer Risk Factors With Tumor Subtypes: A Pooled Analysis From the Breast Cancer Association Consortium Studies

    Xiaohong R. Yang;Jenny Chang-Claude;Ellen L. Goode;Fergus J. Couch

  • Loss of Alleles of Loci on the Short Arm of Chromosome 3 in Renal Cell Carcinoma

    B. Zbar;H. Brauch;C. Talmadge;M. Linehan

  • Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women

    Leila Dorling;Sara Carvalho;Jamie Allen

  • A New Molecular Predictor of Distant Recurrence in ER-Positive, HER2-Negative Breast Cancer Adds Independent Information to Conventional Clinical Risk Factors

    Martin Filipits;Margaretha Rudas;Raimund Jakesz;Peter Dubsky

  • Inherited Mutations in 17 Breast Cancer Susceptibility Genes Among a Large Triple-Negative Breast Cancer Cohort Unselected for Family History of Breast Cancer

    Fergus J. Couch;Steven N. Hart;Priyanka Sharma;Amanda Ewart Toland

  • A common coding variant in CASP8 is associated with breast cancer risk

    Angela Cox;Alison M. Dunning;Montserrat Garcia-Closas;Sabapathy Balasubramanian

  • Prevalence of CD44+/CD24−/low Cells in Breast Cancer May Not Be Associated with Clinical Outcome but May Favor Distant Metastasis

    Benny K. Abraham;Peter Fritz;Monika McClellan;Petra Hauptvogel

  • Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

    John R.B. Perry;Felix Day;Cathy E. Elks;Patrick Sulem

  • Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

    Kyriaki Michailidou;Jonathan Beesley;Sara Lindstrom;Sander Canisius

  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

    Stig E. Bojesen;Stig E. Bojesen;Karen A. Pooley;Sharon E. Johnatty;Jonathan Beesley

  • Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants

    Nasim Mavaddat;Paul D.P. Pharoah;Kyriaki Michailidou;Jonathan Tyrer

  • Association Between CYP2D6 Polymorphisms and Outcomes Among Women With Early Stage Breast Cancer Treated With Tamoxifen

    Werner Schroth;Matthew P. Goetz;Ute Hamann;Peter A. Fasching;Peter A. Fasching

  • MicroRNA related polymorphisms and breast cancer risk

    Sofia Khan;Dario Greco;Dario Greco;Kyriaki Michailidou;Roger L. Milne;Roger L. Milne

Frequent Co-Authors

Graham G. Giles
Graham G. Giles University of Melbourne
Roger L. Milne
Roger L. Milne Cancer Council Victoria
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Ute Hamann
Ute Hamann German Cancer Research Center
Barbara Burwinkel
Barbara Burwinkel Heidelberg University
Melissa C. Southey
Melissa C. Southey Monash University
Stig E. Bojesen
Stig E. Bojesen University of Copenhagen
Per Hall
Per Hall Karolinska Institute
Fergus J. Couch
Fergus J. Couch Mayo Clinic
Douglas F. Easton
Douglas F. Easton University of Cambridge

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