World's Best Scientists 2026 revealed!
Fergus J. Couch

Fergus J. Couch

Award Badge
Genetics
USA
2026

D-Index & Metrics

Genetics

D-Index
143
Citations
94475
World Ranking
169
National Ranking
88

Medicine

D-Index
144
Citations
97838
World Ranking
1419
National Ranking
827

Research.com Recognitions

  • 2026 - Research.com Genetics in United States Leader Award
  • 2025 - Research.com Genetics in United States Leader Award

Overview

Fergus J. Couch is affiliated with the Mayo Clinic in the United States and has an extensive publication record primarily focused on genetics, molecular biology, and oncology within the broader fields of biochemistry, genetics, molecular biology, and medicine. Their research spans key areas including cancer genomics and diagnostics, genetic associations and epidemiology, and DNA repair mechanisms.

Their notable recent scientific contributions include papers published between 2020 and 2021, presenting work in high-impact journals:

  • "Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA" (2020) in Annals of Oncology
  • "A Population-Based Study of Genes Previously Implicated in Breast Cancer" (2021) in New England Journal of Medicine
  • "Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses" (2020) in Nature Genetics
  • "Genetic insights into biological mechanisms governing human ovarian ageing" (2021) in Nature
  • "Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes" (2020) in Nature Genetics

Fergus J. Couch frequently collaborates with a network of researchers, with the most frequent co-authors being:

  • Kathryn J. Ruddy
  • Janet E. Olson
  • Siddhartha Yadav
  • Chunling Hu
  • Peter A. Fasching

Their publication venues indicate a consistent focus on oncology and cancer research, with a high number of contributions appearing in journals such as:

  • Cancer Research
  • Journal of Clinical Oncology
  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Cancer Research

Key topics covered in their work include:

  • BRCA gene mutations in cancer
  • Cancer Genomics and Diagnostics
  • Genetic Associations and Epidemiology
  • Nutrition, Genetics, and Disease
  • Breast Cancer Treatment Studies
  • DNA Repair Mechanisms
  • Genomics and Rare Diseases

Their research contributions have collectively advanced understanding in genetics related to cancer and aging, especially focusing on breast and ovarian cancer, along with complex genetic mechanisms underlying disease susceptibility and progression.

Best Publications

  • Comprehensive molecular portraits of human breast tumours

    Daniel C. Koboldt;Robert S. Fulton;Michael D. McLellan;Heather Schmidt

  • Genome-wide association study identifies novel breast cancer susceptibility loci

    Douglas F. Easton;Karen A. Pooley;Alison M. Dunning;Paul D. P. Pharoah

  • Association of Risk-Reducing Surgery in BRCA1 or BRCA2 Mutation Carriers With Cancer Risk and Mortality

    Susan M. Domchek;Tara M. Friebel;Christian F. Singer;D. Gareth Evans

  • Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies

    Fiona M. Blows;Kristy E. Driver;Marjanka K. Schmidt;Annegien Broeks

  • Association analysis identifies 65 new breast cancer risk loci

    Kyriaki Michailidou;Kyriaki Michailidou;Sara Lindström;Sara Lindström;Joe Dennis;Jonathan Beesley

  • Large-scale genotyping identifies 41 new loci associated with breast cancer risk

    Kyriaki Michailidou;Per Hall;Anna Gonzalez-Neira;Maya Ghoussaini

  • Secondary mutations as a mechanism of cisplatin resistance in BRCA2 -mutated cancers

    Wataru Sakai;Elizabeth M. Swisher;Beth Y. Karlan;Mukesh K. Agarwal

  • The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds.

    S.V. Tavtigian;J. Simard;J. Rommens;F. Couch

  • Breast-Cancer Risk in Families with Mutations in PALB2

    A. C. Antoniou;S. Casadei;T. Heikkinen;D. Barrowdale

  • Control of BRCA2 Cellular and Clinical Functions by a Nuclear Partner, PALB2

    Bing Xia;Qing Sheng;Koji Nakanishi;Akihiro Ohashi

  • RAD51B in Familial Breast Cancer

    Liisa M. Pelttari;Sofia Khan;Mikko Vuorela;Johanna I. Kiiski

  • Gene-Panel Sequencing and the Prediction of Breast-Cancer Risk

    Douglas Frederick Easton;Paul David Pharoah;Antonis C. Antoniou;Marc Derek Tischkowitz

  • Pharmacogenetics of Tamoxifen Biotransformation Is Associated With Clinical Outcomes of Efficacy and Hot Flashes

    Matthew P. Goetz;James M. Rae;Vera J. Suman;Stephanie L. Safgren

  • Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

    Nasim Mavaddat;Kyriaki Michailidou;Kyriaki Michailidou;Joe Dennis;Michael Lush

  • Efficacy of Bilateral Prophylactic Mastectomy in BRCA1 and BRCA2 Gene Mutation Carriers

    Lynn C. Hartmann;Thomas A. Sellers;Daniel J. Schaid;Thomas S. Frank

  • BRCA1 mutations in women attending clinics that evaluate the risk of breast cancer.

    Couch Fj;DeShano Ml;Blackwood Ma;Calzone K

  • Associations of Breast Cancer Risk Factors With Tumor Subtypes: A Pooled Analysis From the Breast Cancer Association Consortium Studies

    Xiaohong R. Yang;Jenny Chang-Claude;Ellen L. Goode;Fergus J. Couch

  • Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

    Junjie Chen;Daniel P. Silver;Deepika Walpita;Sharon B. Cantor

  • Salpingo-oophorectomy and the Risk of Ovarian, Fallopian Tube, and Peritoneal Cancers in Women With a BRCA1 or BRCA2 Mutation

    Amy Finch;Mario Beiner;Jan Lubinski;Henry T. Lynch

  • Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).

    Nasim Mavaddat;Daniel Barrowdale;Irene L. Andrulis;Susan M. Domchek

Frequent Co-Authors

Graham G. Giles
Graham G. Giles University of Melbourne
Hiltrud Brauch
Hiltrud Brauch German Cancer Research Center
Douglas F. Easton
Douglas F. Easton University of Cambridge
Melissa C. Southey
Melissa C. Southey Monash University
Irene L. Andrulis
Irene L. Andrulis University of Toronto
Roger L. Milne
Roger L. Milne Cancer Council Victoria
Georgia Chenevix-Trench
Georgia Chenevix-Trench QIMR Berghofer Medical Research Institute
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Heli Nevanlinna
Heli Nevanlinna University of Helsinki
Paul D.P. Pharoah
Paul D.P. Pharoah University of Cambridge

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Genetics in the USA can open doors to a wide range of related healthcare careers. Many students choose alternative or complementary pathways like medical billing and coding, nursing, or healthcare administration due to flexibility and growing job opportunities.

Many prospective students are concerned with costs—researching how much does it cost to become a medical billing and coding professional can help you plan your education budget more effectively. This career path often offers affordable online programs and provides a quick entry into the healthcare field.

For those interested in patient care, finding what is the easiest nursing program to get into may smooth your transition into healthcare, especially if you’re looking for options with less stringent admission requirements.

Leadership roles in healthcare are also in high demand. Pursuing an online health administration degree can fast-track your qualifications, while those looking for the best value can find the cheapest online healthcare management degree for a cost-effective route into healthcare management.

By considering these related online degrees and career pathways, you can enhance your qualifications and diversify your career options in the dynamic field of healthcare and genetics.

Best Scientists Citing Fergus J. Couch

Trending Scientists

Recently Published Articles