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Leonard K. Kaczmarek

Leonard K. Kaczmarek

D-Index & Metrics

Biology and Biochemistry

D-Index
85
Citations
22258
World Ranking
3196
National Ranking
1616

Overview

Leonard K. Kaczmarek is affiliated with Yale University in the United States. Their research spans across biochemistry, genetics, molecular biology, and neuroscience, with a strong focus on molecular biology and cellular and molecular neuroscience. The subfields they work in include cognitive neuroscience, genetics, and cardiology and cardiovascular medicine.

Their primary research topics cover ion channel regulation and function, neuroscience and neuropharmacology research, genetics and neurodevelopmental disorders, RNA and protein synthesis mechanisms, receptor mechanisms and signaling, cardiac electrophysiology and arrhythmias, and RNA research and splicing.

Recent publications by Leonard K. Kaczmarek include:

  • THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels, 2021, British Journal of Pharmacology
  • The Concise Guide to PHARMACOLOGY 2023/24: Ion channels, 2023, British Journal of Pharmacology
  • Mechanisms underlying auditory processing deficits in Fragile X syndrome, 2020, The FASEB Journal
  • Impaired motor skill learning and altered seizure susceptibility in mice with loss or gain of function of the Kcnt1 gene encoding Slack (KNa1.1) Na+-activated K+ channels, 2020, Scientific Reports
  • LINE-1 activation in the cerebellum drives ataxia, 2022, Neuron

Frequent co-authors collaborating with Kaczmarek are:

  • Jing Wu
  • Yalan Zhang
  • Richard W. Aldrich
  • Stephan Grissmer

Key venues where Leonard K. Kaczmarek publishes include bioRxiv (Cold Spring Harbor Laboratory), Neuron, IUPHAR/BPS Guide to Pharmacology CITE, British Journal of Pharmacology, and The FASEB Journal.

Best Publications

  • High-frequency firing helps replenish the readily releasable pool of synaptic vesicles

    Lu-Yang Wang;Lu-Yang Wang;Leonard K. Kaczmarek

  • Enhancement of calcium current in Aplysia neurones by phorbol ester and protein kinase C

    S. A. DeRiemer;S. A. DeRiemer;J. A. Strong;K. A. Albert;P. Greengard

  • A new family of outwardly rectifying potassium channel proteins with two pore domains in tandem

    Karen A. Ketchum;William J. Joiner;Andrew J. Sellers;Leonard K. Kaczmarek

  • De novo gain-of-function KCNT1 channel mutations cause malignant migrating partial seizures of infancy.

    Giulia Barcia;Matthew R Fleming;Aline Deligniere;Valeswara-Rao Gazula

  • Modulation of mitochondrial function by endogenous Zn2+ pools.

    Stefano L. Sensi;Dien Ton-That;Patrick G. Sullivan;Elizabeth A. Jonas

  • The role of protein kinase C in the regulation of ion channels and neurotransmitter release

    Leonard K. Kaczmarek

  • Cloning and expression of cDNA and genomic clones encoding three delayed rectifier potassium channels in rat brain.

    Richard Swanson;John Marshall;Jeffrey S. Smith;Jacinta B. Williams

  • Contribution of the Kv3.1 potassium channel to high‐frequency firing in mouse auditory neurones

    Lu-Yang Wang;Li Gan;Ian D. Forsythe;Leonard K. Kaczmarek

  • Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase enhances calcium action potentials of bag cell neurons in cell culture

    L. K. Kaczmarek;K. R. Jennings;F. Strumwasser;A. C. Nairn

  • Stimulation of protein kinase C recruits covert calcium channels in Aplysia bag cell neurons.

    J. A. Strong;A. P. Fox;A. P. Fox;R. W. Tsien;L. K. Kaczmarek

  • Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack

    Maile R Brown;Jack Kronengold;Valeswara-Rao Gazula;Yi Chen

  • Expression of the mRNAs for the Kv3.1 potassium channel gene in the adult and developing rat brain.

    T. M. Perney;J. Marshall;K. A. Martin;S. Hockfield

  • Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia

    Marco Onorati;Zhen Li;Fuchen Liu;André M.M. Sousa

  • The Sodium-Activated Potassium Channel Is Encoded by a Member of the Slo Gene Family

    Alex Yuan;Celia M. Santi;Aguan Wei;Zhao Wen Wang

  • hSK4/hIK1, a calmodulin-binding KCa channel in human T lymphocytes. Roles in proliferation and volume regulation.

    Rajesh Khanna;Martin C. Chang;William J. Joiner;Leonard K. Kaczmarek

  • For K+ channels, Na+ is the new Ca2+

    Arin Bhattacharjee;Leonard K. Kaczmarek

  • Clinical whole-genome sequencing in severe early-onset epilepsy reveals new genes and improves molecular diagnosis

    Hilary C. Martin;Grace E. Kim;Alistair T. Pagnamenta;Alistair T. Pagnamenta;Yoshiko Murakami

  • Regulation of potassium channels by protein kinases.

    Elizabeth A Jonas;Leonard K Kaczmarek

  • Cloning and localization of the hyperpolarization-activated cyclic nucleotide-gated channel family in rat brain

    Lisa M Monteggia;Amelia J Eisch;Michael D Tang;Leonard K Kaczmarek

  • Non-conducting functions of voltage-gated ion channels

    Leonard K. Kaczmarek

Frequent Co-Authors

Richard A. Flavell
Richard A. Flavell Yale University
J. Marie Hardwick
J. Marie Hardwick Johns Hopkins University
Lu-Yang Wang
Lu-Yang Wang University of Toronto
Li Gan
Li Gan Cornell University
Tamas L. Horvath
Tamas L. Horvath Yale University
John A. Connor
John A. Connor University of New Mexico
Heike Wulff
Heike Wulff University of California, Davis
Daniel B. Polley
Daniel B. Polley Massachusetts Eye and Ear Infirmary
Charles H. Large
Charles H. Large Autifony Therapeutics (United Kingdom)
Paul Greengard
Paul Greengard Rockefeller University

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