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Biology and Biochemistry
France
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
158
Citations
85397
World Ranking
133
National Ranking
2

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in France Leader Award
  • 2025 - Research.com Biology and Biochemistry in France Leader Award
  • 2023 - Research.com Biology and Biochemistry in France Leader Award
  • 2022 - Research.com Biology and Biochemistry in France Leader Award
  • 2000 - CNRS Gold Medal, French National Centre for Scientific Research Biochemistry
  • 1989 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Michel Lazdunski is affiliated with the Centre national de la recherche scientifique (CNRS) in France. The scientist's research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a significant focus on Medicine. Their work touches on several subfields including Molecular Biology, Cardiology and Cardiovascular Medicine, Cellular and Molecular Neuroscience, Biomedical Engineering, and Pathology and Forensic Medicine.

The research topics covered extensively by Michel Lazdunski involve:

  • Ion channel regulation and function
  • Cardiac electrophysiology and arrhythmias
  • Nicotinic Acetylcholine Receptors Study
  • Neuroscience and Neuropharmacology Research
  • Microfluidic and Capillary Electrophoresis Applications
  • Cardiac Ischemia and Reperfusion

Recent publications authored or co-authored by Michel Lazdunski include:

  • "Selective blockade of Cav1.2 (α1C) versus Cav1.3 (α1D) L-type calcium channels by the black mamba toxin calciseptine" (2024, Nature Communications)
  • "Voltage-gated potassium channels (Kv) in GtoPdb v.2023.1" (2023, IUPHAR/BPS Guide to Pharmacology CITE)
  • "Voltage-gated potassium channels (Kv) in GtoPdb v.2021.3" (2021, IUPHAR/BPS Guide to Pharmacology CITE)
  • "Evidence for a selective blockade of Cav1.2 versus Cav1.3 by the mamba toxin calciseptine in the mouse heart" (2020, Archives of Cardiovascular Diseases Supplements)
  • "Inwardly rectifying potassium channels (KIR) in GtoPdb v.2023.1" (2023, IUPHAR/BPS Guide to Pharmacology CITE)

The frequent collaborators in Michel Lazdunski's body of work include:

  • Lily Yeh Jan
  • Jerry Madukwe
  • Fred Kop
  • Matthew Banks
  • Andrew Bate

Michel Lazdunski publishes often in venues such as IUPHAR/BPS Guide to Pharmacology CITE and Trends in Pharmacological Sciences. Other publication outlets include Nature Communications, Archives of Cardiovascular Diseases Supplements, and Journal of Molecular and Cellular Cardiology Plus.

Awards and recognitions received by Michel Lazdunski include the CNRS Gold Medal from the French National Centre for Scientific Research in 2000 for contributions to Biochemistry. The scientist has also been a member of Academia Europaea since 1989 and holds membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • K v LQT1 and IsK (minK) proteins associate to form the I KS cardiac potassium current

    Jacques Barhanin;Florian Lesage;Eric Guillemare;Michel Fink

  • A proton-gated cation channel involved in acid-sensing

    Rainer Waldmann;Guy Champigny;Frédéric Bassilana;Catherine Heurteaux

  • International Union of Pharmacology. LIII. Nomenclature and Molecular Relationships of Voltage-Gated Potassium Channels

    Aguan D. Wei;George A. Gutman;Richard W Aldrich;K. George Chandy

  • Altered chloride ion channel kinetics associated with the delta F508 cystic fibrosis mutation.

    Wilfried Dalemans;Pascal Barbry;Guy Champigny;Sophie Jallat

  • Essential role of adenosine, adenosine A1 receptors, and ATP-sensitive K+ channels in cerebral ischemic preconditioning

    Catherine Heurteaux;Inger Lauritzen;Catherine Widmann;Michel Lazdunski

  • Inhalational anesthetics activate two-pore-domain background K+ channels.

    Amanda J. Patel;Eric Honoré;Florian Lesage;Michel Fink

  • Molecular and functional properties of two-pore-domain potassium channels

    Florian Lesage;Michel Lazdunski

  • TASK, a human background K+ channel to sense external pH variations near physiological pH.

    Fabrice Duprat;Florian Lesage;Michel Fink;Roberto Reyes

  • A mammalian two pore domain mechano‐gated S‐like K+ channel

    Amanda J. Patel;Eric Honoré;François Maingret;Florian Lesage

  • The sodium/hydrogen exchange system in cardiac cells: its biochemical and pharmacological properties and its role in regulating internal concentrations of sodium and internal pH.

    Michel Lazdunski;Christian Frelin;Paul Vigne

  • TWIK-1, a ubiquitous human weakly inward rectifying K+ channel with a novel structure.

    F. Lesage;E. Guillemare;M. Fink;F. Duprat

  • Molecular cloning of a non-inactivating proton-gated Na+ channel specific for sensory neurons.

    Rainer Waldmann;Frédéric Bassilana;Jan de Weille;Guy Champigny

  • Polyunsaturated fatty acids are potent neuroprotectors

    Inger Lauritzen;Nicolas Blondeau;Catherine Heurteaux;Catherine Widmann

  • Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptors

    Nicolas Voilley;Jan de Weille;Julien Mamet;Michel Lazdunski

  • H+-gated cation channels: neuronal acid sensors in the NaC/DEG family of ion channels

    Rainer Waldmann;Michel Lazdunski

  • TREK-1, a K+ channel involved in neuroprotection and general anesthesia

    C. Heurteaux;N. Guy;C. Laigle;N. Blondeau

  • Glucose, sulfonylureas, and neurotransmitter release: role of ATP-sensitive K+ channels

    Salvatore Amoroso;Heidy Schmid-Antomarchi;Michel Fosset;Michel Lazdunski

  • A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cells.

    Eric Lingueglia;Jan. R. de Weille;Frédéric Bassilana;Catherine Heurteaux

  • International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels : potassium channels

    George A. Gutman;K. George Chandy;John P. Adelman;Jayashree Aiyar

  • TREK-1 is a heat-activated background K(+) channel.

    François Maingret;Inger Lauritzen;Amanda J. Patel;Catherine Heurteaux

Frequent Co-Authors

Florian Lesage
Florian Lesage Centre national de la recherche scientifique, CNRS
Georges Romey
Georges Romey Centre national de la recherche scientifique, CNRS
Catherine Heurteaux
Catherine Heurteaux Centre national de la recherche scientifique, CNRS
Jacques Barhanin
Jacques Barhanin Centre national de la recherche scientifique, CNRS
Michel Fosset
Michel Fosset Centre national de la recherche scientifique, CNRS
Eric Honoré
Eric Honoré Grenoble Alpes University
Christian Frelin
Christian Frelin Centre national de la recherche scientifique, CNRS
Gérard Lambeau
Gérard Lambeau Centre national de la recherche scientifique, CNRS
Paul Vigne
Paul Vigne Grenoble Alpes University
Pascal Barbry
Pascal Barbry Centre national de la recherche scientifique, CNRS

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