The scientist’s investigation covers issues in Amiloride, Biochemistry, Receptor, Biophysics and Cell biology. Paul Vigne combines subjects such as Antiporter, Epithelial sodium channel, Efflux, Stereochemistry and Skeletal muscle with his study of Amiloride. His Receptor research incorporates elements of Molecular biology and Endocrinology.
The concepts of his Biophysics study are interwoven with issues in Angiotensin II, Na+/K+-ATPase and Dissociation constant. In his study, Phosphatidylinositol is strongly linked to Cell culture, which falls under the umbrella field of Cell biology. In P2Y receptor, he works on issues like Adenosine triphosphate, which are connected to Adenosine, Adenylyl cyclase and Platelet activation.
His primary areas of investigation include Biophysics, Biochemistry, Receptor, Endocrinology and Internal medicine. His Biophysics research is multidisciplinary, relying on both Amiloride, Intracellular pH, Intracellular, Myocyte and Na+/K+-ATPase. His Biochemistry research includes elements of Veratridine, Tetrodotoxin and Skeletal muscle.
The various areas that he examines in his Receptor study include Molecular biology, Binding site and Cell biology. His Endocrinology study incorporates themes from Endothelial stem cell, Endothelin receptor, Endothelins, Endothelin 1 and Angiotensin II. His biological study spans a wide range of topics, including Cotransporter and Endoplasmic reticulum.
Paul Vigne mainly investigates Biochemistry, Longevity, Drosophila melanogaster, Endocrinology and Internal medicine. He regularly ties together related areas like Cell biology in his Biochemistry studies. His work deals with themes such as Hypoxia, Yeast and Ageing, which intersect with Longevity.
His work in the fields of Drosophila Protein overlaps with other areas such as Procollagen-proline dioxygenase. His Endocrinology study combines topics from a wide range of disciplines, such as Endothelial stem cell, Ap4A and Adenylate kinase. His Internal medicine study frequently draws parallels with other fields, such as Biophysics.
Paul Vigne spends much of his time researching Fusion protein, Green fluorescent protein, Molecular biology, Procollagen-proline dioxygenase and Biochemistry. His Fusion protein research incorporates themes from Cyclosporin a, Hypoxia-inducible factors and Peptide. His work carried out in the field of Green fluorescent protein brings together such families of science as Transport protein, Drosophila melanogaster, Drosophila Protein and Ubiquitin.
His Molecular biology research integrates issues from 5-HT5A receptor and P2Y receptor. His Procollagen-proline dioxygenase research incorporates Transcription factor, Nuclear protein, Signal transduction, Downregulation and upregulation and Hedgehog signaling pathway. Biochemistry is connected with Protease-activated receptor and Adenosine A2B receptor in his research.
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The sodium/hydrogen exchange system in cardiac cells: its biochemical and pharmacological properties and its role in regulating internal concentrations of sodium and internal pH.
Michel Lazdunski;Christian Frelin;Paul Vigne.
Journal of Molecular and Cellular Cardiology (1985)
A new member of the natriuretic peptide family is present in the venom of the green mamba (Dendroaspis angusticeps).
H Schweitz;P Vigne;D Moinier;C Frelin.
Journal of Biological Chemistry (1992)
The regulation of the intracellular pH in cells from vertebrates.
Christian Frelin;Paul Vigne;Annie Ladoux;Michel Lazdunski.
FEBS Journal (1988)
Molecular mechanism of action of the vasoconstrictor peptide endothelin.
Catherine Van Renterghem;Paul Vigne;Jacques Barhanin;Annie Schmid-Alliana.
Biochemical and Biophysical Research Communications (1988)
Hypoxia Up-regulates Prolyl Hydroxylase Activity A FEEDBACK MECHANSIM THAT LIMITS HIF-1 RESPONSES DURING REOXYGENATION
Gisela D'Angelo;Eric Duplan;Nicole Boyer;Paul Vigne.
Journal of Biological Chemistry (2003)
The P2Y1 Receptor Is Necessary for Adenosine 5′-Diphosphate–Induced Platelet Aggregation
Béatrice Hechler;Catherine Léon;Catherine Léon;Catherine Vial;Catherine Vial;Paul Vigne;Paul Vigne.
Structure-activity relationships of amiloride and certain of its analogues in relation to the blockade of the Na+/H+ exchange system.
P Vigne;C Frelin;E J Cragoe;M Lazdunski.
Molecular Pharmacology (1984)
The role of the Na+/H+ exchange system in cardiac cells in relation to the control of the internal Na+ concentration. A molecular basis for the antagonistic effect of ouabain and amiloride on the heart.
C Frelin;P Vigne;M Lazdunski.
Journal of Biological Chemistry (1984)
Ethylisopropyl-amiloride: a new and highly potent derivative of amiloride for the inhibition of the Na+/H+ exchange system in various cell types.
Paul Vigne;Christian Frelin;Edward J. Cragoe;Michel Lazdunski.
Biochemical and Biophysical Research Communications (1983)
Endothelin stimulates phosphatidylinositol hydrolysis and DNA synthesis in brain capillary endothelial cells.
P Vigne;R Marsault;J P Breittmayer;C Frelin.
Biochemical Journal (1990)
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