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Biology and Biochemistry

D-Index
76
Citations
20595
World Ranking
5049
National Ranking
140

Overview

Jacques Barhanin is affiliated with the Centre national de la recherche scientifique (CNRS) in France. Their research spans key areas within biochemistry, genetics, and molecular biology, as well as medicine.

The scientist's subfields of study focus primarily on molecular biology, with additional specialization in cardiology and cardiovascular medicine, cellular and molecular neuroscience, and oncology.

Barhanin's main research topics include:

  • Ion channel regulation and function
  • Cardiac electrophysiology and arrhythmias
  • Neuroscience and neuropharmacology research
  • Cancer-related gene regulation
  • RNA modifications and cancer
  • Peptidase inhibition and analysis

Among recent publications, the following papers are noted:

  • KCNE1 is an auxiliary subunit of two distinct ion channel superfamilies, 2020, published in Cell
  • The secreted protein augurin is a novel modulator of canonical Wnt signalling involved in osteoblast differentiation, 2022, published in Clinical and Translational Discovery

Frequent collaborators in Barhanin's work include:

  • Pablo Ávalos Prado
  • Stephanie Häfner
  • Yannick Comoglio
  • Brigitte Wdziekonski
  • Christophe Duranton

Barhanin has published in journals such as Cell and Clinical and Translational Discovery, contributing to the fields of molecular biology and related biomedical disciplines.

Best Publications

  • K v LQT1 and IsK (minK) proteins associate to form the I KS cardiac potassium current

    Jacques Barhanin;Florian Lesage;Eric Guillemare;Michel Fink

  • KCNQ1 gain-of-function mutation in familial atrial fibrillation

    Yi-Han Chen;Shi-Jie Xu;Shi-Jie Xu;Saı̈d Bendahhou;Xiao-Liang Wang

  • A novel mutation in the potassium channel gene KVLQT1 causes the Jervell and Lange-Nielsen cardioauditory syndrome

    Nathalie Neyroud;Frédérique Tesson;Isabelle Denjoy;Michel Leibovici

  • TWIK-1, a ubiquitous human weakly inward rectifying K+ channel with a novel structure.

    F. Lesage;E. Guillemare;M. Fink;F. Duprat

  • Identification of a KCNE2 Gain-of-Function Mutation in Patients with Familial Atrial Fibrillation

    Yiqing Yang;Min Xia;Qingfeng Jin;Saïd Bendahhou

  • Inner Ear Defects Induced by Null Mutation of the isk Gene

    Douglas E Vetter;Jeffrey R Mann;Philine Wangemann;Jianzhong Liu

  • A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation.

    Min Xia;Qingfeng Jin;Saïd Bendahhou;Yusong He

  • Genetic and Molecular Basis of Cardiac Arrhythmias: Impact on Clinical Management Parts I and II

    Silvia G. Priori;Jacques Barhanin;Richard N. W. Hauer;Wilhelm Haverkamp

  • Molecular mechanism of action of the vasoconstrictor peptide endothelin.

    Catherine Van Renterghem;Paul Vigne;Jacques Barhanin;Annie Schmid-Alliana

  • Cloning and expression of a membrane receptor for secretory phospholipases A2.

    G Lambeau;P Ancian;J Barhanin;M Lazdunski

  • Role of α9 Nicotinic ACh Receptor Subunits in the Development and Function of Cochlear Efferent Innervation

    Douglas E Vetter;M.Charles Liberman;Jeffrey Mann;Jacques Barhanin

  • Properties of KvLQT1 K+ channel mutations in Romano–Ward and Jervell and Lange-Nielsen inherited cardiac arrhythmias

    Christophe Chouabe;Nathalie Neyroud;Pascale Guicheney;Michel Lazdunski

  • KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel

    Norbert Tinel;Sylvie Diochot;Marc Borsotto;Michel Lazdunski

  • Molecular properties of neuronal G-protein-activated inwardly rectifying K^+ channels

    Florian Lesage;Eric Guillemare;Michel Fink;Fabrice Duprat

  • External blockade of the major cardiac delayed-rectifier K+ channel (Kv1.5) by polyunsaturated fatty acids.

    Eric Honore;Jacques Barhanin;Bernard Attali;Florian Lesage

  • Characterization and photoaffinity labeling of receptor sites for the Ca2+ channel inhibitors d-cis-diltiazem, (+/-)-bepridil, desmethoxyverapamil, and (+)-PN 200-110 in skeletal muscle transverse tubule membranes.

    J P Galizzi;M Borsotto;J Barhanin;M Fosset

  • Genetic and molecular basis of cardiac arrhythmias; impact on clinical management. Study group on molecular basis of arrhythmias of the working group on arrhythmias of the european society of cardiology.

    S.G. Priori;J. Barhanin;R.N.W. Hauer;W. Haverkamp

  • The 1,4-dihydropyridine receptor associated with the skeletal muscle voltage-dependent Ca2+ channel. Purification and subunit composition.

    M Borsotto;J Barhanin;M Fosset;M Lazdunski

  • Identification and properties of very high affinity brain membrane-binding sites for a neurotoxic phospholipase from the taipan venom.

    G. Lambeau;J. Barhanin;H. Schweitz;Janti Qar

  • Invalidation of TASK1 potassium channels disrupts adrenal gland zonation and mineralocorticoid homeostasis.

    Dirk Heitzmann;Renaud Derand;Stefan Jungbauer;Sascha Bandulik

Frequent Co-Authors

Michel Lazdunski
Michel Lazdunski Centre national de la recherche scientifique, CNRS
Florian Lesage
Florian Lesage Centre national de la recherche scientifique, CNRS
Georges Romey
Georges Romey Centre national de la recherche scientifique, CNRS
Michel Fosset
Michel Fosset Centre national de la recherche scientifique, CNRS
Eric Honoré
Eric Honoré Grenoble Alpes University
Enzo Lalli
Enzo Lalli Centre national de la recherche scientifique, CNRS
Christian Frelin
Christian Frelin Centre national de la recherche scientifique, CNRS
Gérard Lambeau
Gérard Lambeau Centre national de la recherche scientifique, CNRS
Jean-Pierre Vincent
Jean-Pierre Vincent Centre national de la recherche scientifique, CNRS
Ez-Zoubir Amri
Ez-Zoubir Amri Grenoble Alpes University

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