What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Potassium channel, Biophysics, Biochemistry, Inward-rectifier potassium ion channel and Amino acid.
His Potassium channel research integrates issues from Hyperpolarization, Arachidonic acid, COS cells, Patch clamp and Pharmacology.
His research integrates issues of Extracellular, Xenopus, Central nervous system and Protein kinase A in his study of Biophysics.
His biological study spans a wide range of topics, including Potassium channel blocker and Cell biology.
The study incorporates disciplines such as Voltage-gated ion channel, Ligand-gated ion channel and G protein, G protein-coupled inwardly-rectifying potassium channel in addition to Inward-rectifier potassium ion channel.
His Amino acid research is multidisciplinary, incorporating elements of Quinidine, Tetraethylammonium, Molecular biology and Membrane potential.
His most cited work include:
- K v LQT1 and IsK (minK) proteins associate to form the I KS cardiac potassium current (1421 citations)
- TASK, a human background K+ channel to sense external pH variations near physiological pH. (558 citations)
- Inhalational anesthetics activate two-pore-domain background K+ channels. (546 citations)
What are the main themes of his work throughout his whole career to date?
Potassium channel, Biophysics, Biochemistry, Cell biology and Molecular biology are his primary areas of study.
Florian Lesage has researched Potassium channel in several fields, including Neuroscience, Membrane potential, Ion channel, Inward-rectifier potassium ion channel and Cloning.
His research in Inward-rectifier potassium ion channel intersects with topics in Gating, Voltage-gated ion channel, G protein, K2p channel and Cell type.
His study focuses on the intersection of Biophysics and fields such as Ligand-gated ion channel with connections in the field of SK channel.
His Cell biology research is multidisciplinary, incorporating perspectives in Genetics, Stimulation, Membrane protein and In situ hybridization.
His studies in Molecular biology integrate themes in fields like Xenopus, Messenger RNA, Gene, Transmembrane domain and Myocyte.
He most often published in these fields:
- Potassium channel (44.12%)
- Biophysics (27.06%)
- Biochemistry (25.88%)
What were the highlights of his more recent work (between 2014-2021)?
- Potassium channel (44.12%)
- Neuroscience (12.94%)
- Cell biology (21.76%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Potassium channel, Neuroscience, Cell biology, Gating and Ion channel.
His Potassium channel research is classified as research in Biophysics.
The various areas that Florian Lesage examines in his Biophysics study include Amino acid, Ligand-gated ion channel, SK channel and Caenorhabditis elegans.
His Neuroscience study combines topics in areas such as Eukaryotic translation, Receptor, Gene and Immune system.
His Cell biology research is multidisciplinary, relying on both Recombinant DNA, Tyrosine, Membrane protein and Membrane lipids.
His work is dedicated to discovering how Gating, Inward-rectifier potassium ion channel are connected with Endosome, Transmembrane channels, Voltage-gated ion channel and Endoplasmic reticulum and other disciplines.
Between 2014 and 2021, his most popular works were:
- The family of K2P channels: salient structural and functional properties (108 citations)
- Migraine-Associated TRESK Mutations Increase Neuronal Excitability through Alternative Translation Initiation and Inhibition of TREK. (44 citations)
- Mixing and matching TREK/TRAAK subunits generate heterodimeric K2P channels with unique properties (37 citations)
In his most recent research, the most cited papers focused on:
Florian Lesage mainly focuses on Potassium channel, Neuroscience, In vivo, Phenotype and Gating.
His study in Neuroscience is interdisciplinary in nature, drawing from both Receptor and Gene.
Gene is a subfield of Biochemistry that Florian Lesage explores.
Florian Lesage interconnects Electrophysiology, Agonist, Analgesic, TWIK-RELATED K+ CHANNEL and Stereochemistry in the investigation of issues within In vivo.
His Gating research entails a greater understanding of Biophysics.
His work in Biophysics addresses subjects such as Membrane protein, which are connected to disciplines such as Pharmacology.
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