His primary areas of investigation include Potassium channel, Biophysics, Biochemistry, Inward-rectifier potassium ion channel and Amino acid. His Potassium channel research integrates issues from Hyperpolarization, Arachidonic acid, COS cells, Patch clamp and Pharmacology. His research integrates issues of Extracellular, Xenopus, Central nervous system and Protein kinase A in his study of Biophysics.
His biological study spans a wide range of topics, including Potassium channel blocker and Cell biology. The study incorporates disciplines such as Voltage-gated ion channel, Ligand-gated ion channel and G protein, G protein-coupled inwardly-rectifying potassium channel in addition to Inward-rectifier potassium ion channel. His Amino acid research is multidisciplinary, incorporating elements of Quinidine, Tetraethylammonium, Molecular biology and Membrane potential.
Potassium channel, Biophysics, Biochemistry, Cell biology and Molecular biology are his primary areas of study. Florian Lesage has researched Potassium channel in several fields, including Neuroscience, Membrane potential, Ion channel, Inward-rectifier potassium ion channel and Cloning. His research in Inward-rectifier potassium ion channel intersects with topics in Gating, Voltage-gated ion channel, G protein, K2p channel and Cell type.
His study focuses on the intersection of Biophysics and fields such as Ligand-gated ion channel with connections in the field of SK channel. His Cell biology research is multidisciplinary, incorporating perspectives in Genetics, Stimulation, Membrane protein and In situ hybridization. His studies in Molecular biology integrate themes in fields like Xenopus, Messenger RNA, Gene, Transmembrane domain and Myocyte.
His scientific interests lie mostly in Potassium channel, Neuroscience, Cell biology, Gating and Ion channel. His Potassium channel research is classified as research in Biophysics. The various areas that Florian Lesage examines in his Biophysics study include Amino acid, Ligand-gated ion channel, SK channel and Caenorhabditis elegans.
His Neuroscience study combines topics in areas such as Eukaryotic translation, Receptor, Gene and Immune system. His Cell biology research is multidisciplinary, relying on both Recombinant DNA, Tyrosine, Membrane protein and Membrane lipids. His work is dedicated to discovering how Gating, Inward-rectifier potassium ion channel are connected with Endosome, Transmembrane channels, Voltage-gated ion channel and Endoplasmic reticulum and other disciplines.
Florian Lesage mainly focuses on Potassium channel, Neuroscience, In vivo, Phenotype and Gating. His study in Neuroscience is interdisciplinary in nature, drawing from both Receptor and Gene. Gene is a subfield of Biochemistry that Florian Lesage explores.
Florian Lesage interconnects Electrophysiology, Agonist, Analgesic, TWIK-RELATED K+ CHANNEL and Stereochemistry in the investigation of issues within In vivo. His Gating research entails a greater understanding of Biophysics. His work in Biophysics addresses subjects such as Membrane protein, which are connected to disciplines such as Pharmacology.
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K v LQT1 and IsK (minK) proteins associate to form the I KS cardiac potassium current
Jacques Barhanin;Florian Lesage;Eric Guillemare;Michel Fink.
Inhalational anesthetics activate two-pore-domain background K+ channels.
Amanda J. Patel;Eric Honoré;Florian Lesage;Michel Fink.
Nature Neuroscience (1999)
Molecular and functional properties of two-pore-domain potassium channels
Florian Lesage;Michel Lazdunski.
American Journal of Physiology-renal Physiology (2000)
TASK, a human background K+ channel to sense external pH variations near physiological pH.
Fabrice Duprat;Florian Lesage;Michel Fink;Roberto Reyes.
The EMBO Journal (1997)
A mammalian two pore domain mechano‐gated S‐like K+ channel
Amanda J. Patel;Eric Honoré;François Maingret;Florian Lesage.
The EMBO Journal (1998)
TWIK-1, a ubiquitous human weakly inward rectifying K+ channel with a novel structure.
F. Lesage;E. Guillemare;M. Fink;F. Duprat.
The EMBO Journal (1996)
International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels : potassium channels
George A. Gutman;K. George Chandy;John P. Adelman;Jayashree Aiyar.
Pharmacological Reviews (2003)
A neuronal two P domain K+ channel stimulated by arachidonic acid and polyunsaturated fatty acids
Michel Fink;Florian Lesage;Fabrice Duprat;Catherine Heurteaux.
The EMBO Journal (1998)
TREK-1 is a heat-activated background K(+) channel.
François Maingret;Inger Lauritzen;Amanda J. Patel;Catherine Heurteaux.
The EMBO Journal (2000)
Cloning, functional expression and brain localization of a novel unconventional outward rectifier K+ channel.
M Fink;F Duprat;F Lesage;R Reyes.
The EMBO Journal (1996)
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