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D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
20888
World Ranking
6228
National Ranking
150

Research.com Recognitions

  • 2013 - Fellow of the Australian Academy of Science

Overview

Boris Martinac is affiliated with the Victor Chang Cardiac Research Institute in Australia. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, alongside Medicine. Within these broad fields, their work addresses several specialized subfields including Molecular Biology, Physiology, Cell Biology, Biomedical Engineering, and Pulmonary and Respiratory Medicine.

Their scientific contributions cover topics such as Erythrocyte Function and Pathophysiology, Ion channel regulation and function, Lipid Membrane Structure and Behavior, Cellular Mechanics and Interactions, Blood properties and coagulation, Microfluidic and Bio-sensing Technologies, and Ion Channels and Receptors.

Martinac has published numerous papers, including several recent ones notable for their focus on mechanosensitive ion channels and membrane biophysics. Examples of these publications include:

  • Disruption of membrane cholesterol organization impairs the activity of PIEZO1 channel clusters, 2020, The Journal of General Physiology
  • Visualization of the mechanosensitive ion channel MscS under membrane tension, 2021, Nature
  • Force- and cell state-dependent recruitment of Piezo1 drives focal adhesion dynamics and calcium entry, 2022, Science Advances
  • Piezo1 Forms Specific, Functionally Important Interactions with Phosphoinositides and Cholesterol, 2020, Biophysical Journal
  • Piezo1 is the cardiac mechanosensor that initiates the cardiomyocyte hypertrophic response to pressure overload in adult mice, 2022, Nature Cardiovascular Research

Among frequent collaborators, Martinac has worked extensively with Charles D. Cox, Yang Guo, Ze-Yan Yu, Michael P. Feneley, and Scott Kesteven.

Their research has appeared often in venues such as bioRxiv (Cold Spring Harbor Laboratory), Biophysical Journal, Biophysical Reviews, Nature Communications, and the International Journal of Molecular Sciences.

In recognition of their scientific contributions, Martinac was named a Fellow of the Australian Academy of Science in 2013.

Best Publications

  • Molecular basis of mechanotransduction in living cells

    Owen P. Hamill;Boris Martinac

  • A large-conductance mechanosensitive channel in E. coli encoded by mscL alone

    Sergei I. Sukharev;Paul Blount;Boris Martinac;Boris Martinac;Frederick R. Blattner

  • Pressure-sensitive ion channel in Escherichia coli.

    Boris Martinac;Matthew Buechner;Anne H. Delcour;Julius Adler

  • Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating

    Eduardo Perozo;Anna Kloda;D. Marien Cortes;Boris Martinac

  • TRPC1 forms the stretch-activated cation channel in vertebrate cells

    Rosario Maroto;Albert Raso;Thomas G. Wood;Alex Kurosky

  • Open channel structure of MscL and the gating mechanism of mechanosensitive channels

    Eduardo Perozo;D. Marien Cortes;Pornthep Sompornpisut;Pornthep Sompornpisut;Anna Kloda

  • Mechanosensitive ion channels: molecules of mechanotransduction

    Boris Martinac

  • Mechanosensitive ion channels of E. coli activated by amphipaths.

    Boris Martinac;Julius Adler;Ching Kung

  • Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension

    Charles D. Cox;Chilman Bae;Lynn Ziegler;Silas Hartley

  • Piezo1 Channels Are Inherently Mechanosensitive.

    Ruhma Syeda;Maria N. Florendo;Charles D. Cox;Jennifer M. Kefauver

  • A mechanosensitive ion channel in the yeast plasma membrane.

    Michael C. Gustin;Xin-Liang Zhou;Boris Martinac;Ching Kung

  • Mechanosensitive channels of Escherichia coli: the MscL gene, protein, and activities.

    Sergei I. Sukharev;Paul Blount;Boris Martinac;Ching Kung

  • Two types of mechanosensitive channels in the Escherichia coli cell envelope: solubilization and functional reconstitution.

    S. I. Sukharev;B. Martinac;V. Y. Arshavsky;Ching Kung

  • Mechanosensitive Channels in Microbes

    Ching Kung;Boris Martinac;Sergei Sukharev

  • Estimation of the pore size of the large-conductance mechanosensitive ion channel of Escherichia coli

    Chris Cruickshank;R.F. Minchin;A.C. Le Dain;B. Martinac

  • Revisiting TRPC1 and TRPC6 mechanosensitivity

    Philip Gottlieb;Joost Folgering;Rosario Maroto;Albert Raso

  • Modified reconstitution method used in patch-clamp studies of Escherichia coli ion channels

    A. H. Delcour;B. Martinac;J. Adler;Ching Kung

  • Purification and Functional Reconstitution of the Recombinant Large Mechanosensitive Ion Channel (MscL) of Escherichia coli

    C C Häse;A C Le Dain;B Martinac

  • Ion Channels in Microbes

    Boris Martinac;Yoshiro Saimi;Ching Kung

  • Open channel structure of MscL and the gating mechanism of mechanosensitive

    D. Marien Cortes;Pornthep Sompornpisut;Anna Kloda;Boris Martinac

Frequent Co-Authors

Ching Kung
Ching Kung University of Wisconsin–Madison
Robert M. Graham
Robert M. Graham Victor Chang Cardiac Research Institute
Julius Adler
Julius Adler University of Wisconsin–Madison
Eduardo Perozo
Eduardo Perozo University of Chicago
Anne S. Ulrich
Anne S. Ulrich Karlsruhe Institute of Technology
Masahiro Sokabe
Masahiro Sokabe Nagoya University
Michael R. Culbertson
Michael R. Culbertson University of Wisconsin–Madison
Frederick Sachs
Frederick Sachs University at Buffalo, State University of New York
Reinhard Krämer
Reinhard Krämer University of Cologne
Thomas Walz
Thomas Walz Rockefeller University

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