H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology D-index 53 Citations 9,144 125 World Ranking 2420 National Ranking 1172

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Internal medicine
  • Enzyme

Lin Leng spends much of her time researching Macrophage migration inhibitory factor, Cytokine, Immunology, Signal transduction and Cancer research. Her Macrophage migration inhibitory factor study combines topics in areas such as Proinflammatory cytokine, CD74, Endocrinology and Cell biology. Her studies deal with areas such as Apoptosis, Erythropoiesis, Haematopoiesis and Pathogenesis as well as Cytokine.

Lin Leng interconnects Receptor and Bronchoalveolar lavage in the investigation of issues within Immunology. Her research integrates issues of Cell surface receptor, Ischemia and Kinase, Protein kinase A in her study of Signal transduction. Her biological study spans a wide range of topics, including Gene expression, CXC chemokine receptors, Chemokine receptor, Receptor complex and Transforming growth factor beta.

Her most cited work include:

  • MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment (890 citations)
  • MIF signal transduction initiated by binding to CD74. (789 citations)
  • CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex. (442 citations)

What are the main themes of her work throughout her whole career to date?

The scientist’s investigation covers issues in Macrophage migration inhibitory factor, Immunology, Cytokine, Internal medicine and Endocrinology. Her Macrophage migration inhibitory factor research is multidisciplinary, incorporating elements of Cancer research, Inflammation, Proinflammatory cytokine, CD74 and Cell biology. In her study, Receptor complex and Kinase is strongly linked to Signal transduction, which falls under the umbrella field of Cancer research.

Her research in Immunology intersects with topics in Macrophage, Allele and Genotype. Her work carried out in the field of Cytokine brings together such families of science as Tumor necrosis factor alpha, Biological activity, CXC chemokine receptors and Monocyte. Her research in Endocrinology tackles topics such as AMPK which are related to areas like Ischemia.

She most often published in these fields:

  • Macrophage migration inhibitory factor (81.58%)
  • Immunology (39.04%)
  • Cytokine (26.32%)

What were the highlights of her more recent work (between 2016-2021)?

  • Macrophage migration inhibitory factor (81.58%)
  • Immunology (39.04%)
  • Cancer research (17.98%)

In recent papers she was focusing on the following fields of study:

Macrophage migration inhibitory factor, Immunology, Cancer research, Cytokine and Internal medicine are her primary areas of study. Her Macrophage migration inhibitory factor research incorporates themes from Pathogenesis, Inflammation, Proinflammatory cytokine, CD74 and Downregulation and upregulation. Her CD74 study integrates concerns from other disciplines, such as Receptor, CXCR4 and Cell biology.

Her study on Antibody is often connected to Granulomatosis with polyangiitis as part of broader study in Immunology. Lin Leng combines subjects such as SNP, Oxidative stress, Pericyte, Myosin light-chain kinase and Necroptosis with her study of Cytokine. The Internal medicine study combines topics in areas such as Endocrinology and Genotype.

Between 2016 and 2021, her most popular works were:

  • MIF and D-DT are potential disease severity modifiers in male MS subjects (46 citations)
  • MIF family cytokines in cardiovascular diseases and prospects for precision-based therapeutics (33 citations)
  • The protective role of macrophage migration inhibitory factor in acute kidney injury after cardiac surgery (32 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Enzyme

Lin Leng focuses on Macrophage migration inhibitory factor, Immunology, CD74, Cytokine and Cancer research. Her Macrophage migration inhibitory factor study improves the overall literature in Internal medicine. Her Immunology research is multidisciplinary, incorporating perspectives in Signal transduction, Activating transcription factor and Receptor complex.

As part of the same scientific family, Lin Leng usually focuses on CD74, concentrating on Disease and intersecting with Genotype, Multiple sclerosis and Clinically isolated syndrome. The concepts of her Cytokine study are interwoven with issues in Oxidative stress, Hypoxia, CXCR4, Pathogenesis and CXC chemokine receptors. Her Cancer research research includes themes of Tumor microenvironment, T cell, Myeloid-derived Suppressor Cell, Cytotoxic T cell and Immunotherapy.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment

Jürgen Bernhagen;Regina Krohn;Hongqi Lue;Julia L Gregory.
Nature Medicine (2007)

1169 Citations

MIF signal transduction initiated by binding to CD74.

Lin Leng;Christine N. Metz;Yan Fang;Jing Xu.
Journal of Experimental Medicine (2003)

1056 Citations

CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex.

Xuerong Shi;Lin Leng;Tian Wang;Wenkui Wang.
Immunity (2006)

607 Citations

Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart

Edward J. Miller;Ji Li;Lin Leng;Courtney McDonald.
Nature (2008)

508 Citations

Macrophage migration inhibitory factor.

Lin Leng;Richard Bucala.
Critical Care Medicine (2005)

360 Citations

Macrophage migration inhibitory factor (MIF) promotes cell survival by activation of the akt pathway and role for CSN5/JAB1 in the control of autocrine MIF activity

H Lue;M Thiele;J Franz;E Dahl.
Oncogene (2007)

357 Citations

High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers.

Toshiya Atsumi;Jason Chesney;Christine Metz;Lin Leng.
Cancer Research (2002)

342 Citations

Inhibition of macrophage migration inhibitory factor or its receptor (CD74) attenuates growth and invasion of DU-145 prostate cancer cells.

Katherine L. Meyer-Siegler;Katherine L. Meyer-Siegler;Kenneth A. Iczkowski;Kenneth A. Iczkowski;Lin Leng;Richard Bucala.
Journal of Immunology (2006)

301 Citations

Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activity.

Hongqi Lue;Aphrodite Kapurniotu;Günter Fingerle-Rowson;Thierry Roger.
Cellular Signalling (2006)

256 Citations

Macrophage Migration Inhibitory Factor Induces B Cell Survival by Activation of a CD74-CD44 Receptor Complex

Yael Gore;Diana Starlets;Nitsan Maharshak;Shirly Becker-Herman.
Journal of Biological Chemistry (2008)

241 Citations

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Best Scientists Citing Lin Leng

Richard Bucala

Richard Bucala

Yale University

Publications: 111

Christian Weber

Christian Weber

Ludwig Maximilian University of Munich

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Jürgen Bernhagen

Jürgen Bernhagen

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Eric F. Morand

Eric F. Morand

Monash University

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Jun Ren

Jun Ren

Fudan University

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Thierry Calandra

Thierry Calandra

University of Lausanne

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Christine N. Metz

Christine N. Metz

Feinstein Institute for Medical Research

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Stefan Magez

Stefan Magez

Ghent University

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Thierry Roger

Thierry Roger

University of Lausanne

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Abhay R. Satoskar

Abhay R. Satoskar

The Ohio State University

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Halina Offner

Halina Offner

Oregon Health & Science University

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Arthur A. Vandenbark

Arthur A. Vandenbark

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Paul Ashwood

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Ferdinando Nicoletti

Ferdinando Nicoletti

Sapienza University of Rome

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Anthony M. Dart

Anthony M. Dart

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