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Biology and Biochemistry

D-Index
63
Citations
16252
World Ranking
10106
National Ranking
4422

Overview

Huabao Xiong is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research primarily focuses on immunology, microbiology, and medicine, with significant contributions in biochemistry, genetics, and molecular biology. Throughout their career, Xiong has published extensively on various aspects of immune response, inflammation, and cancer research.

The main fields of study covered in Xiong's work include:

  • Immunology and Microbiology
  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these fields, their work is further specialized in subfields such as:

  • Immunology
  • Molecular Biology
  • Oncology
  • Epidemiology
  • Cancer Research

Xiong's research topics show a strong focus on immune system dynamics and their interaction with diseases, including cancer. The main topics they have worked on include:

  • Immune Response and Inflammation
  • Immune Cell Function and Interaction
  • Immune cells in cancer
  • T-cell and B-cell Immunology
  • Adenosine and Purinergic Signaling
  • Cytokine Signaling Pathways and Interactions
  • NF-κB Signaling Pathways

Frequent publication venues for Xiong's work reflect a strong presence in immunology and related interdisciplinary fields. Key journals include:

  • Frontiers in Immunology
  • International Immunopharmacology
  • Proceedings of the National Academy of Sciences
  • Inflammation
  • UNC Libraries

Some recent papers authored or co-authored by Huabao Xiong illustrate the breadth of their research interests and collaborative efforts. Selected recent papers are:

  • "Implications of NKG2A in immunity and immune-mediated diseases," 2022, Frontiers in Immunology
  • "The implications of FASN in immune cell biology and related diseases," 2024, Cell Death and Disease
  • "Link of sorafenib resistance with the tumor microenvironment in hepatocellular carcinoma: Mechanistic insights," 2022, Frontiers in Pharmacology
  • "AQP5 complements LGR5 to determine the fates of gastric cancer stem cells through regulating ULK1 ubiquitination," 2022, Journal of Experimental & Clinical Cancer Research
  • "IL-17B/IL-17RB signaling cascade contributes to self-renewal and tumorigenesis of cancer stem cells by regulating Beclin-1 ubiquitination," 2021, Oncogene

Collaborations feature prominently in Xiong's work. Frequent co-authors include:

  • Guanjun Dong
  • Fenglian Yan
  • Junfeng Zhang
  • Zhaochen Ning
  • Mingsheng Zhao

Best Publications

  • The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

    Chen Zhu;Ana C Anderson;Anna Schubart;Huabao Xiong

  • Toll-Like Receptors on Tumor Cells Facilitate Evasion of Immune Surveillance

    Bo Huang;Jie Zhao;Hongxing Li;Kai-Li He

  • Interaction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: implications for virus fusogenic mechanism and identification of fusion inhibitors.

    Shuwen Liu;Gengfu Xiao;Yibang Chen;Yuxian He

  • Mucus Enhances Gut Homeostasis and Oral Tolerance by Delivering Immunoregulatory Signals

    Meimei Shan;Maurizio Gentile;John R. Yeiser;A. Cooper Walland

  • TLR signaling by tumor and immune cells: a double-edged sword.

    B Huang;J Zhao;J C Unkeless;Z H Feng

  • GM-CSF Controls Nonlymphoid Tissue Dendritic Cell Homeostasis but Is Dispensable for the Differentiation of Inflammatory Dendritic Cells

    Melanie Greter;Julie Helft;Andrew Chow;Daigo Hashimoto

  • The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88

    Bing He;Raul Santamaria;Weifeng Xu;Montserrat Cols

  • SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment

    Bo Huang;Zhang Lei;Gui-Mei Zhang;Dong Li

  • Regulation of iNOS on Immune Cells and Its Role in Diseases.

    Qingjie Xue;Yingchun Yan;Ruihua Zhang;Huabao Xiong

  • Interleukin 10 suppresses Th17 cytokines secreted by macrophages and T cells

    Yongpeng Gu;Jianfei Yang;Xinshou Ouyang;Weicheng Liu

  • Enteroendocrine cells express functional Toll-like receptors

    Milena Bogunovic;Shaival H. Davé;Jeremy S. Tilstra;Diane T. W. Chang

  • Cutting edge: autoantigen Ro52 is an interferon inducible E3 ligase that ubiquitinates IRF-8 and enhances cytokine expression in macrophages.

    Hee Jeong Kong;Hee Jeong Kong;D. Eric Anderson;Chang Hoon Lee;Moon Kyoo Jang

  • Listeria monocytogenes Promotes Tumor Growth via Tumor Cell Toll-Like Receptor 2 Signaling

    Bo Huang;Jie Zhao;Shiqian Shen;Hongxing Li

  • The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF)

    Melanie Merk;Swen Zierow;Lin Leng;Rituparna Das

  • Myeloid cell-derived inducible nitric oxide synthase suppresses M1 macrophage polarization

    Geming Lu;Ruihua Zhang;Shuo Geng;Liang Peng

  • IRF-8/Interferon (IFN) Consensus Sequence-binding Protein Is Involved in Toll-like Receptor (TLR) Signaling and Contributes to the Cross-talk between TLR and IFN-γ Signaling Pathways

    Jie Zhao;Hee Jeong Kong;Hongxing Li;Bo Huang

  • The persistence of low-grade inflammatory monocytes contributes to aggravated Atherosclerosis

    Shuo Geng;Keqiang Chen;Ruoxi Yuan;Liang Peng

  • A Tautomerase-Null Macrophage Migration-Inhibitory Factor (MIF) Gene Knock-In Mouse Model Reveals That Protein Interactions and Not Enzymatic Activity Mediate MIF-Dependent Growth Regulation

    Giinter Fingerle-Rowson;Dayananda Rao Kaleswarapu;Corinna Schlander;Nazanin Kabgani

  • AP-1 Activated by Toll-like Receptors Regulates Expression of IL-23 p19

    Weicheng Liu;Xinshou Ouyang;Jianjun Yang;Jianguo Liu

  • Endothelial cell annexin A2 regulates polyubiquitination and degradation of its binding partner S100A10/p11.

    Kai-Li He;Arunkumar B. Deora;Huabao Xiong;Qi Ling

Frequent Co-Authors

Lloyd Mayer
Lloyd Mayer Icahn School of Medicine at Mount Sinai
Keiko Ozato
Keiko Ozato Eunice Kennedy Shriver National Institute of Child Health and Human Development
Jay C. Unkeless
Jay C. Unkeless Icahn School of Medicine at Mount Sinai
Herbert C. Morse
Herbert C. Morse National Institute of Allergy and Infectious Diseases
Liwu Li
Liwu Li Virginia Tech
Kebin Liu
Kebin Liu Augusta University
Ming-Ming Zhou
Ming-Ming Zhou Icahn School of Medicine at Mount Sinai
Richard Bucala
Richard Bucala Yale University
Miriam Merad
Miriam Merad Icahn School of Medicine at Mount Sinai
Lin Leng
Lin Leng Yale University

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