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D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
13384
World Ranking
10272
National Ranking
4477

Overview

Kebin Liu is affiliated with Augusta University in the United States and has contributed extensively to fields intersecting medicine, biochemistry, genetics, molecular biology, immunology, and microbiology. Their research predominantly focuses on immunology, molecular biology, oncology, pulmonary and respiratory medicine, and cancer research.

Their scientific work explores several main topics, including:

  • Immune cells in cancer
  • Cancer Immunotherapy and Biomarkers
  • Immune Cell Function and Interaction
  • Ferroptosis and cancer prognosis
  • Epigenetics and DNA Methylation
  • Immunotherapy and Immune Responses
  • Cancer Research and Treatments

Kebin Liu's recent notable publications include:

  • "Osteopontin: A Key Regulator of Tumor Progression and Immunomodulation" (2020) published in Cancers
  • "Asah2 Represses the p53-Hmox1 Axis to Protect Myeloid-Derived Suppressor Cells from Ferroptosis" (2021) published in The Journal of Immunology
  • "WDR5-H3K4me3 epigenetic axis regulates OPN expression to compensate PD-L1 function to promote pancreatic cancer immune escape" (2021) published in Journal for ImmunoTherapy of Cancer
  • "Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment" (2023) published in Cancer Cell
  • "Autocrine IL6-Mediated Activation of the STAT3-DNMT Axis Silences the TNFα-RIP1 Necroptosis Pathway to Sustain Survival and Accumulation of Myeloid-Derived Suppressor Cells" (2020) published in Cancer Research

Their contributions appear frequently in several publication venues, particularly:

  • The Journal of Immunology (8 publications)
  • Cancer Research (8 publications)
  • Cancers (4 publications)
  • Journal for ImmunoTherapy of Cancer (4 publications)
  • ACS Nano (3 publications)

Kebin Liu collaborates regularly with a group of researchers, including:

  • John D. Klement (26 collaborations)
  • Dafeng Yang (24 collaborations)
  • Chunwan Lu (20 collaborations)
  • Dakota B. Poschel (18 collaborations)
  • Priscilla S. Redd (14 collaborations)

The scientific work carried out by Kebin Liu integrates elements of immune regulation within cancer biology, with particular attention to myeloid-derived suppressor cells, immune checkpoint pathways, ferroptosis, and epigenetic modulation in tumor microenvironments. Their research addresses mechanisms that influence tumor progression and immune escape, contributing knowledge relevant to cancer immunotherapy development and immune cell functionality in cancer settings.

Best Publications

  • A2A adenosine receptor protects tumors from antitumor T cells

    Akio Ohta;Elieser Gorelik;Simon J. Prasad;Franca Ronchese

  • GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon

    Muthusamy Thangaraju;Gail A. Cresci;Kebin Liu;Sudha Ananth

  • Irradiation of tumor cells up-regulates Fas and enhances CTL lytic activity and CTL adoptive immunotherapy

    Mala Chakraborty;Scott I. Abrams;Kevin Camphausen;Kebin Liu

  • Autophagy is a renoprotective mechanism during in vitro hypoxia and in vivo ischemia-reperfusion injury.

    Man Jiang;Kebin Liu;Jia Luo;Zheng Dong

  • Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis

    Jeremy D. Waight;Colleen Netherby;Mary L. Hensen;Austin Miller

  • Cutting Edge: Telomerase Activation in Human T Lymphocytes Does Not Require Increase in Telomerase Reverse Transcriptase (hTERT) Protein But Is Associated with hTERT Phosphorylation and Nuclear Translocation

    Kebin Liu;Richard J. Hodes;Nan-ping Weng

  • Constitutive and regulated expression of telomerase reverse transcriptase (hTERT) in human lymphocytes

    Kebin Liu;Michele M. Schoonmaker;Bruce L. Levine;Carl H. June

  • An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion

    John D. Klement;Amy V. Paschall;Amy V. Paschall;Priscilla S. Redd;Priscilla S. Redd;Mohammed L. Ibrahim

  • The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity.

    Navjotsingh Pabla;Robert F. Murphy;Kebin Liu;Zheng Dong

  • Butyrate suppresses colonic inflammation through HDAC1-dependent Fas Upregulation and Fas-mediated apoptosis of T cells

    Mary A. Zimmerman;Nagendra Singh;Pamela Moore Martin;Muthusamy Thangaraju

  • Epigenetics and Colorectal Cancer Pathogenesis

    Kankana Bardhan;Kebin Liu

  • The MLL1-H3K4me3 Axis-Mediated PD-L1 Expression and Pancreatic Cancer Immune Evasion.

    Chunwan Lu;Amy V. Paschall;Huidong Shi;Natasha Savage

  • IL-15 mimics T cell receptor crosslinking in the induction of cellular proliferation, gene expression, and cytotoxicity in CD8+ memory T cells.

    Kebin Liu;Marta Catalfamo;Yu Li;Pierre A. Henkart

  • Myeloid cell-derived inducible nitric oxide synthase suppresses M1 macrophage polarization

    Geming Lu;Ruihua Zhang;Shuo Geng;Liang Peng

  • Extracellular Signal–Regulated Kinase Signaling Pathway Regulates Breast Cancer Cell Migration by Maintaining slug Expression

    Haoming Chen;Genfeng Zhu;Yong Li;Ravi N. Padia

  • The expression profiles and regulation of PD-L1 in tumor-induced myeloid-derived suppressor cells

    Chunwan Lu;Priscilla S. Redd;Jeffrey R. Lee;Natasha Savage

  • Tubular p53 Regulates Multiple Genes to Mediate AKI

    Dongshan Zhang;Yu Liu;Yu Liu;Qingqing Wei;Yuqing Huo

  • NF-κB Directly Regulates Fas Transcription to Modulate Fas-mediated Apoptosis and Tumor Suppression

    Feiyan Liu;Feiyan Liu;Kankana Bardhan;Dafeng Yang;Muthusamy Thangaraju

  • Colonic gene expression in conventional and germ-free mice with a focus on the butyrate receptor GPR109A and the butyrate transporter SLC5A8.

    Gail A. Cresci;Muthusamy Thangaraju;John D. Mellinger;Kebin Liu

  • JAK-STAT-mediated chronic inflammation impairs cytotoxic T lymphocyte activation to decrease anti-PD-1 immunotherapy efficacy in pancreatic cancer

    Chunwan Lu;Asif Talukder;Natasha M. Savage;Nagendra Singh

Frequent Co-Authors

Scott I. Abrams
Scott I. Abrams Roswell Park Cancer Institute
Vadivel Ganapathy
Vadivel Ganapathy Texas Tech University Health Sciences Center
Muthusamy Thangaraju
Muthusamy Thangaraju Augusta University
Zheng Dong
Zheng Dong Augusta University
Keiko Ozato
Keiko Ozato Eunice Kennedy Shriver National Institute of Child Health and Human Development
Huabao Xiong
Huabao Xiong Icahn School of Medicine at Mount Sinai
Sylvia B. Smith
Sylvia B. Smith Augusta University
Nicholas H. Oberlies
Nicholas H. Oberlies University of North Carolina at Greensboro
Andrew L. Mellor
Andrew L. Mellor Newcastle University
Mark W. Grinstaff
Mark W. Grinstaff Boston University

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