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Immunology

D-Index
56
Citations
12553
World Ranking
3702
National Ranking
1705

Overview

Scott I. Abrams is affiliated with the Roswell Park Cancer Institute in the United States. Their research extensively covers multiple aspects of cancer biology, immunology, and molecular biology, with a focus on cancer immunotherapy and immune system interactions within the tumor microenvironment.

The primary fields of study for this scientist include Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Their subfields of expertise delve into Immunology, Oncology, Molecular Biology, Cancer Research, and Pulmonary and Respiratory Medicine.

Among the main topics explored in their research are:

  • Cancer Immunotherapy and Biomarkers
  • Immune cells in cancer
  • Immunotherapy and Immune Responses
  • Immune Cell Function and Interaction
  • Cancer Cells and Metastasis
  • CAR-T cell therapy research
  • Cancer, Hypoxia, and Metabolism

Scott I. Abrams has contributed to a number of scientific papers, some of the recent publications being:

  • Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer, 2022, Cancer Cell
  • Platelet glycoprotein VI promotes metastasis through interaction with cancer cell-derived Galectin-3, 2020, Blood
  • Overcoming primary and acquired resistance to anti-PD-L1 therapy by induction and activation of tumor-residing cDC1s, 2020, Nature Communications
  • β2-adrenergic receptor signaling regulates metabolic pathways critical to myeloid-derived suppressor cell function within the TME, 2021, Cell Reports
  • Breast Tumor Microenvironment in Black Women: A Distinct Signature of CD8+ T-Cell Exhaustion, 2020, JNCI Journal of the National Cancer Institute

Their frequent collaborators include:

  • Jason B. Muhitch
  • Brian Morreale
  • Fumito Ito
  • Kazuaki Takabe
  • Mark D. Long

Scott I. Abrams publishes regularly in several scientific journals. Notable frequent publication venues are:

  • Cancer Research
  • The Journal of Immunology
  • Annals of Surgical Oncology
  • Journal for ImmunoTherapy of Cancer
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • A2A adenosine receptor protects tumors from antitumor T cells

    Akio Ohta;Elieser Gorelik;Simon J. Prasad;Franca Ronchese

  • Irradiation of tumor cells up-regulates Fas and enhances CTL lytic activity and CTL adoptive immunotherapy

    Mala Chakraborty;Scott I. Abrams;Kevin Camphausen;Kebin Liu

  • External beam radiation of tumors alters phenotype of tumor cells to render them susceptible to vaccine-mediated T-cell killing.

    Mala Chakraborty;Scott I. Abrams;C. Norman Coleman;Kevin Camphausen

  • Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer.

    Unknown

  • Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis

    Jeremy D. Waight;Colleen Netherby;Mary L. Hensen;Austin Miller

  • Baseline tumor growth and immune control in laboratory mice are significantly influenced by subthermoneutral housing temperature

    Kathleen M. Kokolus;Maegan L. Capitano;Chen-Ting Lee;Jason W.-L. Eng

  • An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion

    John D. Klement;Amy V. Paschall;Amy V. Paschall;Priscilla S. Redd;Priscilla S. Redd;Mohammed L. Ibrahim

  • Tumor-Derived G-CSF Facilitates Neoplastic Growth through a Granulocytic Myeloid-Derived Suppressor Cell-Dependent Mechanism

    Jeremy D. Waight;Qiang Hu;Austin Miller;Song Liu

  • Antitumor Activity and Immune Responses Induced by a Recombinant Carcinoembryonic Antigen-Vaccinia Virus Vaccine

    Judy Kantor;Kari Irvine;Scott Abrams;Howard Kaufman

  • β2 adrenergic receptor–mediated signaling regulates the immunosuppressive potential of myeloid-derived suppressor cells

    Hemn Mohammadpour;Cameron R. MacDonald;Guanxi Qiao;Minhui Chen

  • β-adrenergic signaling in mice housed at standard temperatures suppresses an effector phenotype in CD8+ T cells and undermines checkpoint inhibitor therapy

    Mark J. Bucsek;Guanxi Qiao;Cameron R. MacDonald;Thejaswini Giridharan

  • Immune Response to a Carcinoembryonic Antigen Polynucleotide Vaccine

    Robert M. Conry;Albert F. LoBuglio;Judith Kantor;Jeffrey Schlom

  • Cancer in primary immunodeficiency diseases: Cancer incidence in the United States Immune Deficiency Network Registry

    Paul C. Mayor;Kevin H. Eng;Kelly L. Singel;Scott I. Abrams

  • How tumours escape mass destruction

    Trina Stewart;S.I. Abrams;S.I. Abrams

  • Induction of Antitumor Immunity by Recombinant Vaccinia Viruses Expressing B7-1 or B7-2 Costimulatory Molecules

    James W. Hodge;Scott Abrams;Jeffrey Schlom;Judy A. Kantor

  • Targeting CXCL12/CXCR4 signaling with oncolytic virotherapy disrupts tumor vasculature and inhibits breast cancer metastases

    Margaret Gil;Mukund Seshadri;Marcin P. Komorowski;Scott I. Abrams

  • Bortezomib and Depsipeptide Sensitize Tumors to Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand: A Novel Method to Potentiate Natural Killer Cell Tumor Cytotoxicity

    Andreas Lundqvist;Scott I. Abrams;David S. Schrump;Gauri Alvarez

  • A phase I vaccine trial with peptides reflecting ras oncogene mutations of solid tumors.

    S N Khleif;S I Abrams;J M Hamilton;E Bergmann-Leitner

  • Immunogenicity and safety of a recombinant vaccinia virus vaccine expressing the carcinoembryonic antigen gene in a nonhuman primate.

    J. Kantor;K. Irvine;S. Abrams;P. Snoy

  • Platelet glycoprotein VI promotes metastasis through interaction with cancer cell-derived galectin-3

    Elmina Mammadova-Bach;Jesus Gil-Pulido;Edita Sarukhanyan;Philipp Burkard

  • Admixture of a Recombinant Vaccinia Virus Containing the Gene for the Costimulatory Molecule B7 and a Recombinant Vaccinia Virus Containing a Tumor-associated Antigen Gene Results in Enhanced Specific T-Cell Responses and Antitumor Immunity

    J W Hodge;J P McLaughlin;S I Abrams;W L Shupert

  • Treatment of human colon carcinoma cell lines with anti-neoplastic agents enhances their lytic sensitivity to antigen-specific CD8+ cytotoxic T lymphocytes

    Elke S. Bergmann-Leitner;Scott I. Abrams

Frequent Co-Authors

Kebin Liu
Kebin Liu Augusta University
Jeffrey Schlom
Jeffrey Schlom National Institutes of Health
Brahm H. Segal
Brahm H. Segal Roswell Park Cancer Institute
Kunle Odunsi
Kunle Odunsi Roswell Park Cancer Institute
Elizabeth A. Repasky
Elizabeth A. Repasky Roswell Park Cancer Institute
James W. Hodge
James W. Hodge National Institutes of Health
Kelvin P. Lee
Kelvin P. Lee Roswell Park Comprehensive Cancer Center
Keiko Ozato
Keiko Ozato Eunice Kennedy Shriver National Institute of Child Health and Human Development
Paul K. Wallace
Paul K. Wallace Roswell Park Cancer Institute
Agnieszka K. Witkiewicz
Agnieszka K. Witkiewicz Roswell Park Cancer Institute

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