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Biology and Biochemistry

D-Index
46
Citations
13520
World Ranking
18832
National Ranking
555

Overview

Paul A. Beavis is affiliated with the Peter MacCallum Cancer Centre in Australia. Their research focuses primarily on immunology, oncology, and molecular biology, with extensive publications across these fields.

Key areas of study for Paul A. Beavis include:

  • Immunology and Microbiology
  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within subfields, their work spans:

  • Immunology
  • Oncology
  • Molecular Biology
  • Genetics
  • Electrical and Electronic Engineering

The main topics of their research cover a range of subjects, including:

  • CAR-T cell therapy research
  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • Cancer Immunotherapy and Biomarkers
  • CRISPR and Genetic Engineering
  • T-cell and B-cell Immunology
  • Viral Infectious Diseases and Gene Expression in Insects

Prominent recent publications reflect these research interests:

  • Targeting the epigenetic regulation of antitumour immunity, 2020, Nature Reviews Drug Discovery
  • Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion, 2020, Cancer Research
  • Tissue-resident memory T cells in breast cancer control and immunotherapy responses, 2020, Nature Reviews Clinical Oncology
  • Sex-specific adipose tissue imprinting of regulatory T cells, 2020, Nature
  • Cellular networks controlling T cell persistence in adoptive cell therapy, 2021, Nature Reviews Immunology

Paul A. Beavis collaborates frequently with other researchers. Notable co-authors include:

  • Phillip K. Darcy
  • Imran G. House
  • Kevin Sek
  • Junyun Lai
  • Amanda X. Y. Chen

Their work is regularly published in several venues, with multiple contributions to:

  • Cancer Cell
  • Nature
  • Nature Communications
  • Cancer Research
  • Immunity

Best Publications

  • Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis

    Peter Savas;Balaji Virassamy;Chengzhong Ye;Agus Salim;Agus Salim

  • CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity

    Marian L Burr;Marian L Burr;Marian L Burr;Christina E Sparbier;Yih-Chih Chan;James C Williamson

  • Anti-PD-1 Antibody Therapy Potently Enhances the Eradication of Established Tumors By Gene-Modified T Cells

    Liza B John;Christel Devaud;Connie P M Duong;Carmen S M Yong

  • Macrophage-Derived CXCL9 and CXCL10 Are Required for Antitumor Immune Responses Following Immune Checkpoint Blockade.

    Imran G House;Imran G House;Peter Savas;Peter Savas;Junyun Lai;Junyun Lai;Amanda X. Y. Chen;Amanda X. Y. Chen

  • RAS/MAPK activation is associated with reduced tumor-infiltrating lymphocytes in triple-negative breast cancer: therapeutic cooperation between MEK and PD-1/PD-L1 immune checkpoint inhibitors

    Sherene Loi;Sherene Loi;Sathana Dushyanthen;Paul A. Beavis;Roberto Salgado

  • CD73 promotes anthracycline resistance and poor prognosis in triple negative breast cancer

    Sherene Loi;Sandra Pommey;Benjamin Haibe-Kains;Paul A Beavis

  • An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer

    Marian L. Burr;Marian L. Burr;Marian L. Burr;Christina E. Sparbier;Christina E. Sparbier;Kah Lok Chan;Kah Lok Chan;Yih-Chih Chan

  • CD73: a potent suppressor of antitumor immune responses

    Paul. A. Beavis;John Stagg;Phillip K. Darcy;Phillip K. Darcy;Mark J. Smyth;Mark J. Smyth

  • Targeting the epigenetic regulation of antitumour immunity.

    Simon J Hogg;Simon J Hogg;Simon J Hogg;Paul A Beavis;Paul A Beavis;Mark A Dawson;Mark A Dawson;Ricky W Johnstone;Ricky W Johnstone

  • Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion.

    Florida Voli;Emanuele Valli;Luigi Lerra;Kathleen Kimpton

  • Tumor immune evasion arises through loss of TNF sensitivity

    Conor J. Kearney;Conor J. Kearney;Stephin J. Vervoort;Stephin J. Vervoort;Simon J. Hogg;Simon J. Hogg;Kelly M. Ramsbottom

  • Blockade of A2A receptors potently suppresses the metastasis of CD73+ tumors

    Paul A. Beavis;Upulie Divisekera;Upulie Divisekera;Christophe Paget;Christophe Paget;Melvyn T. Chow;Melvyn T. Chow

  • Chimeric antigen receptor T cells form nonclassical and potent immune synapses driving rapid cytotoxicity.

    A J Davenport;R S Cross;R S Cross;K A Watson;Y Liao

  • Adenosine Receptor 2A Blockade Increases the Efficacy of Anti–PD-1 through Enhanced Antitumor T-cell Responses

    Paul A. Beavis;Paul A. Beavis;Nicole Milenkovski;Nicole Milenkovski;Melissa A. Henderson;Melissa A. Henderson;Liza B. John;Liza B. John

  • Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacy

    Paul A. Beavis;Paul A. Beavis;Melissa A. Henderson;Melissa A. Henderson;Lauren Giuffrida;Lauren Giuffrida;Jane K. Mills;Jane K. Mills

  • Tissue-resident memory T cells in breast cancer control and immunotherapy responses

    Ann Byrne;Peter Savas;Peter Savas;Sneha Sant;Sneha Sant;Ran Li;Ran Li

  • BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1.

    Simon J. Hogg;Stephin J. Vervoort;Sumit Deswal;Christopher J. Ott

  • Immunosuppressive activities of adenosine in cancer.

    Bertrand Allard;Paul A Beavis;Phillip K Darcy;John Stagg

  • Relevance of tumor-infiltrating lymphocytes in breast cancer

    Sathana Dushyanthen;Paul A. Beavis;Peter Savas;Zhi Ling Teo

  • CD73-deficient mice are resistant to carcinogenesis.

    John Stagg;Paul A. Beavis;Upulie Divisekera;Mira C.P. Liu

Frequent Co-Authors

Phillip K. Darcy
Phillip K. Darcy Peter MacCallum Cancer Centre
Sherene Loi
Sherene Loi Peter MacCallum Cancer Centre
Michael H. Kershaw
Michael H. Kershaw Peter MacCallum Cancer Centre
Joseph A. Trapani
Joseph A. Trapani Peter MacCallum Cancer Centre
Ricky W. Johnstone
Ricky W. Johnstone Peter MacCallum Cancer Centre
Mark J. Smyth
Mark J. Smyth QIMR Berghofer Medical Research Institute
Ilia Voskoboinik
Ilia Voskoboinik Peter MacCallum Cancer Centre
Tony Tiganis
Tony Tiganis Peter MacCallum Cancer Centre
Benjamin Solomon
Benjamin Solomon Peter MacCallum Cancer Centre
Robert G. Ramsay
Robert G. Ramsay Peter MacCallum Cancer Centre

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