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Biology and Biochemistry

D-Index
73
Citations
31625
World Ranking
5799
National Ranking
2742

Medicine

D-Index
73
Citations
31658
World Ranking
19540
National Ranking
9727

Overview

Justin M. Balko is affiliated with Vanderbilt University Medical Center in the United States, focusing on biomedical research primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their scientific output spans multiple subfields, particularly Oncology, Immunology, Molecular Biology, Cancer Research, and Pulmonary and Respiratory Medicine.

The scientist's research concentrates on topics related to cancer and immune response, with significant attention to Cancer Immunotherapy and Biomarkers, Immunotherapy and Immune Responses, and Cancer Genomics and Diagnostics. Their work also explores areas such as CAR-T cell therapy research, Immune Cell Function and Interaction, Immune cells in cancer, and Chemokine receptors and signaling.

Justin M. Balko has published extensively, with notable papers including:

  • Immune-checkpoint inhibitors: long-term implications of toxicity, 2022, Nature Reviews Clinical Oncology
  • T cells specific for α-myosin drive immunotherapy-related myocarditis, 2022, Nature
  • A Genetic Mouse Model Recapitulates Immune Checkpoint Inhibitor-Associated Myocarditis and Supports a Mechanism-Based Therapeutic Intervention, 2020, Cancer Discovery
  • A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti-PD-1 immunotherapy, 2020, Journal of Clinical Investigation
  • Multi-omics analysis identifies therapeutic vulnerabilities in triple-negative breast cancer subtypes, 2021, Nature Communications

The frequent publication venues for their work include:

  • Cancer Research
  • Regular and Young Investigator Award Abstracts
  • Journal of Clinical Oncology
  • Clinical Cancer Research
  • UNC Libraries

Collaboration is a notable aspect of this scientist's career, with frequent co-authors being:

  • Paula I. González-Ericsson
  • Douglas B. Johnson
  • Melinda E. Sanders
  • Violeta Sánchez
  • Xiaopeng Sun

Best Publications

  • Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease

    Giampaolo Bianchini;Justin M. Balko;Ingrid A. Mayer;Melinda E. Sanders

  • Fulminant Myocarditis with Combination Immune Checkpoint Blockade

    Douglas B. Johnson;Justin M. Balko;Margaret L. Compton;Spyridon Chalkias

  • Fatal Toxic Effects Associated With Immune Checkpoint Inhibitors: A Systematic Review and Meta-analysis

    Daniel Y. Wang;Joe Elie Salem;Joe Elie Salem;Justine V. Cohen;Sunandana Chandra

  • Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data

    Francesca Finotello;Clemens Mayer;Christina Plattner;Gerhard Laschober

  • Cardiovascular toxicities associated with immune checkpoint inhibitors: an observational, retrospective, pharmacovigilance study.

    Joe-Elie Salem;Joe-Elie Salem;Ali Manouchehri;Melissa Moey;Bénédicte Lebrun-Vignes

  • Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group Part 2 TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non–Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourinary Carcinomas, and Primary Brain Tumors

    Shona Hendry;Roberto Salgado;Thomas Gevaert;Prudence A. Russell;Prudence A. Russell

  • Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in Invasive Breast Carcinoma and Ductal Carcinoma in Situ, Metastatic Tumor Deposits and Areas for Further Research

    Shona Hendry;Roberto Salgado;Thomas Gevaert;Prudence A. Russell;Prudence A. Russell

  • Emergence of constitutively active estrogen receptor-α mutations in pretreated advanced estrogen receptor positive breast cancer

    Rinath Jeselsohn;Roman Yelensky;Gilles Buchwalter;Gilles Buchwalter;Garrett Frampton

  • RAS/MAPK activation is associated with reduced tumor-infiltrating lymphocytes in triple-negative breast cancer: therapeutic cooperation between MEK and PD-1/PD-L1 immune checkpoint inhibitors

    Sherene Loi;Sherene Loi;Sathana Dushyanthen;Paul A. Beavis;Roberto Salgado

  • MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation

    Kyung min Lee;Jennifer M. Giltnane;Justin M. Balko;Luis J. Schwarz

  • TGF-β inhibition enhances chemotherapy action against triple-negative breast cancer

    Neil E. Bhola;Justin M. Balko;Teresa C. Dugger;María Gabriela Kuba

  • Endosomolytic Polymersomes Increase the Activity of Cyclic Dinucleotide STING Agonists to Enhance Cancer Immunotherapy

    Daniel Shae;Kyle W. Becker;Plamen Christov;Dong Soo Yun

  • Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets

    Justin M. Balko;Jennifer M. Giltnane;Kai Wang;Luis J. Schwarz

  • Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy

    Douglas B. Johnson;Monica V. Estrada;Roberto Salgado;Violeta Sanchez

  • Targeted Next Generation Sequencing Identifies Markers of Response to PD-1 Blockade

    Douglas B. Johnson;Garrett M. Frampton;Matthew J. Rioth;Erik Yusko

  • Phosphatidylinositol 3-Kinase and Antiestrogen Resistance in Breast Cancer

    Todd W. Miller;Justin M. Balko;Carlos L. Arteaga

  • ERα-dependent E2F transcription can mediate resistance to estrogen deprivation in human breast cancer

    Todd W. Miller;Justin M. Balko;Emily M. Fox;Zara Ghazoui

  • PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors

    Brian D Lehmann;Joshua A Bauer;Johanna M Schafer;Christopher S Pendleton

  • Biological Consequences of MHC-II Expression by Tumor Cells in Cancer.

    Margaret L. Axelrod;Margaret L. Axelrod;Rebecca S. Cook;Douglas B. Johnson;Douglas B. Johnson;Justin M. Balko;Justin M. Balko

  • A Phase Ib Study of Alpelisib (BYL719), a PI3Kα-Specific Inhibitor, with Letrozole in ER+/HER2- Metastatic Breast Cancer.

    Ingrid A. Mayer;Vandana Abramson;Luigi Formisano;Justin M Balko

Frequent Co-Authors

Carlos L. Arteaga
Carlos L. Arteaga The University of Texas Southwestern Medical Center
Douglas B. Johnson
Douglas B. Johnson Vanderbilt University Medical Center
Ingrid A. Mayer
Ingrid A. Mayer Vanderbilt University Medical Center
Roberto Salgado
Roberto Salgado Peter MacCallum Cancer Centre
Sherene Loi
Sherene Loi Peter MacCallum Cancer Centre
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University
David L. Rimm
David L. Rimm Yale University
Javid Moslehi
Javid Moslehi University of California, San Francisco
Jeffrey A. Sosman
Jeffrey A. Sosman Northwestern University

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