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Jo A. Van Ginderachter

Jo A. Van Ginderachter

D-Index & Metrics

Immunology

D-Index
63
Citations
24224
World Ranking
2977
National Ranking
40

Overview

Jo A. Van Ginderachter is affiliated with Vrije Universiteit Brussel in Belgium and contributes to research primarily in immunology and related biomedical fields. Their work spans immunology and microbiology, medicine, and biochemistry, genetics, and molecular biology. The scientist's research includes significant focus on subfields such as immunology, molecular biology, oncology, radiology, nuclear medicine, imaging, and neurology.

Their scholarly activities cover a range of topics including immune cells in cancer, immunotherapy and immune responses, immune cell function and interaction, monoclonal and polyclonal antibodies research, neuroinflammation and neurodegeneration mechanisms, cancer immunotherapy and biomarkers, and CAR-T cell therapy research.

Jo A. Van Ginderachter has published multiple papers in frequent collaboration with several coauthors. The most frequent coauthors include Damya Laoui, Yvon Elkrim, Daliya Kancheva, Kiavash Movahedi, and Benoît Stijlemans.

The scientist's publications often appear in notable venues such as Frontiers in Immunology, Cancers, Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), and SSRN Electronic Journal.

Representative recent papers include:

  • Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization, 2021, Nature Neuroscience
  • Understanding the glioblastoma immune microenvironment as basis for the development of new immunotherapeutic strategies, 2020, eLife
  • Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy, 2021, Journal for ImmunoTherapy of Cancer
  • Macrophages are metabolically heterogeneous within the tumor microenvironment, 2021, Cell Reports
  • Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation, 2022, Immunity

Best Publications

  • Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

    Peter J Murray;Judith E Allen;Subhra K Biswas;Edward A Fisher

  • Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell–suppressive activity

    Kiavash Movahedi;Martin Guilliams;Jan Van den Bossche;Rafael Van den Bergh

  • Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) Monocytes

    Kiavash Movahedi;Damya Laoui;Conny Gysemans;Martijn Baeten

  • A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment.

    Hannah Van Hove;Liesbet Martens;Isabelle Scheyltjens;Karen De Vlaminck

  • HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF.

    Charlotte Rolny;Massimiliano Mazzone;Sònia Tugues;Damya Laoui

  • Impeding Macrophage Entry into Hypoxic Tumor Areas by Sema3A/Nrp1 Signaling Blockade Inhibits Angiogenesis and Restores Antitumor Immunity

    Andrea Casazza;Damya Laoui;Mathias Wenes;Sabrina Rizzolio

  • Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization.

    Ana Rita Pombo Antunes;Isabelle Scheyltjens;Francesca Lodi;Julie Messiaen

  • Classical and alternative activation of mononuclear phagocytes: picking the best of both worlds for tumor promotion.

    Jo A. Van Ginderachter;Kiavash Movahedi;Gholamreza Hassanzadeh Ghassabeh;Sofie Meerschaut

  • Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity

    Kim Vriens;Stefan Christen;Sweta Parik;Dorien Broekaert

  • Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population

    Damya Laoui;Eva Van Overmeire;Giusy Di Conza;Chiara Aldeni

  • Tumor-associated macrophages in breast cancer: distinct subsets, distinct functions

    Damya Laoui;Kiavash Movahedi;Eva Van Overmeire;Jan Van den Bossche

  • Nanobody-Based Targeting of the Macrophage Mannose Receptor for Effective In Vivo Imaging of Tumor-Associated Macrophages

    Kiavash Movahedi;Steve Schoonooghe;Damya Laoui;Isabelle Houbracken

  • Macrophage Metabolism As Therapeutic Target for Cancer, Atherosclerosis, and Obesity

    Xenia Geeraerts;Evangelia Bolli;Sarah-Maria Fendt;Jo A. Van Ginderachter

  • Molecular profiling reveals a tumor-promoting phenotype of monocytes and macrophages in human cancer progression.

    Manesh Chittezhath;Manprit Kaur Dhillon;Jyue Yuan Lim;Damya Laoui

  • The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity.

    Damya Laoui;Jiri Keirsse;Yannick Morias;Eva Van Overmeire

  • The transcription factor ZEB2 is required to maintain the tissue-specific identities of macrophages

    Charlotte L. Scott;Charlotte L. Scott;Wouter T’Jonck;Liesbet Martens;Helena Todorov

  • Understanding the glioblastoma immune microenvironment as basis for the development of new immunotherapeutic strategies.

    Ana Rita Pombo Antunes;Isabelle Scheyltjens;Johnny Duerinck;Bart Neyns

  • M-CSF and GM-CSF Receptor Signaling Differentially Regulate Monocyte Maturation and Macrophage Polarization in the Tumor Microenvironment

    Eva Van Overmeire;Benoît Stijlemans;Felix Heymann;Jiri Keirsse

  • Functional Relationship between Tumor-Associated Macrophages and Macrophage Colony-Stimulating Factor as Contributors to Cancer Progression

    Damya Laoui;Eva Van Overmeire;Patrick De Baetselier;Jo A. Van Ginderachter

  • Podoplanin-Expressing Macrophages Promote Lymphangiogenesis and Lymphoinvasion in Breast Cancer

    Paweł Bieniasz-Krzywiec;Rosa Martín-Pérez;Manuel Ehling;Melissa García-Caballero

  • Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T-CELL suppressive activity

    Kiavash Movahedi;Martin Guiliams;Jan Van den Bossche;Rafael Van den Bergh

Frequent Co-Authors

Patrick De Baetselier
Patrick De Baetselier Vrije Universiteit Brussel
Geert Raes
Geert Raes Vrije Universiteit Brussel
Alain Beschin
Alain Beschin Vrije Universiteit Brussel
Stefan Magez
Stefan Magez Ghent University
Karin Vanderkerken
Karin Vanderkerken Vrije Universiteit Brussel
Karine Breckpot
Karine Breckpot Vrije Universiteit Brussel
Martin Guilliams
Martin Guilliams Ghent University
Thierry VandenDriessche
Thierry VandenDriessche Vrije Universiteit Brussel

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Related Online Degrees & Career Pathways

Studying Immunology in the USA opens doors to various interdisciplinary healthcare careers. Many students interested in immunology also explore nursing due to its practical applications in patient care and disease management.

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If you seek a faster route into nursing, easiest accelerated nursing programs offer intensive curricula designed to get you into the workforce quickly. Similarly, easy lpn programs to get into provide streamlined entry points for licensed practical nurses aiming to build clinical expertise relevant to immunology.

For advanced practice roles, easiest np program options are ideal for those aiming to specialize further, combining immunological knowledge with direct patient care. These pathways complement immunology studies by broadening career potential in healthcare.

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