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Fumitake Gejyo

Fumitake Gejyo

D-Index & Metrics

Medicine

D-Index
79
Citations
20827
World Ranking
17658
National Ranking
563

Overview

Fumitake Gejyo is affiliated with Niigata University in Japan, with research focused primarily on medicine and biochemistry, genetics, and molecular biology. Their work spans several subfields, including molecular biology, physiology, dermatology, rheumatology, and nephrology. The scientist's research topics include amyloidosis diagnosis and treatment, dermatology and skin diseases, Alzheimer's disease research, urticaria and related conditions, asthma and respiratory diseases, dialysis and renal disease management, and gastrointestinal motility and disorders.

Among the recent papers authored or coauthored by Fumitake Gejyo are the following:

  • Efficacy and Safety of Difelikefalin in Japanese Patients With Moderate to Severe Pruritus Receiving Hemodialysis, 2022, JAMA Network Open
  • Macromolecular crowding and supersaturation protect hemodialysis patients from the onset of dialysis-related amyloidosis, 2022, Nature Communications
  • Difelikefalin for Hemodialysis Patients with Pruritus in Japan, 2023, NEJM Evidence
  • Mass spectrometry-based proteomic analysis of proteins adsorbed by hexadecyl-immobilized cellulose bead column for the treatment of dialysis-related amyloidosis, 2024, Amyloid
  • Long-term efficacy and safety of difelikefalin in moderate-to-severe pruritus in Japanese hemodialysis patients: a 52-week open-label extension period of a phase 3 trial, 2024, Renal Replacement Therapy

Frequent coauthors of Gejyo have included Ichiei Narita, Suguru Yamamoto, Yoshiharu Tsubakihara, Takuma Uchiyama, and Shota Okamura, with multiple collaborative publications.

The scientist's work has been published in various peer-reviewed journals, including:

  • JAMA Network Open
  • Nature Communications
  • NEJM Evidence
  • Amyloid
  • Renal Replacement Therapy

Fumitake Gejyo's research often addresses clinical and molecular aspects of kidney-related conditions, including dialysis-related amyloidosis and pruritus in hemodialysis patients. The investigation of difelikefalin, a therapeutic agent for pruritus in this patient group, appears prominently in their recent contributions.

Best Publications

  • A new form of amyloid protein associated with chronic hemodialysis was identified as β2-microglobulin

    F. Gejyo;T. Yamada;S. Odani;Y. Nakagawa

  • Augmentation of Vα14 Nkt Cell–Mediated Cytotoxicity by Interleukin 4 in an Autocrine Mechanism Resulting in the Development of Concanavalin a–Induced Hepatitis

    Yoshikatsu Kaneko;Michishige Harada;Tetsu Kawano;Masakatsu Yamashita

  • Etiology and prognostic significance of severe uremic pruritus in chronic hemodialysis patients.

    I. Narita;B. Alchi;K. Omori;F. Sato

  • Beta 2-microglobulin: a new form of amyloid protein associated with chronic hemodialysis.

    Fumitake Gejyo;Shoji Odani;Toshiyuki Yamada;Noriyuki Honma

  • Possible involvement of circulating fibroblast growth factor 23 in the development of secondary hyperparathyroidism associated with renal insufficiency.

    Takashi Shigematsu;Junichiro James Kazama;Takeyoshi Yamashita;Seiji Fukumoto

  • Eradication of established tumors in mice by a combination antibody-based therapy.

    Tomoyasu Uno;Kazuyoshi Takeda;Kazuyoshi Takeda;Yuko Kojima;Hirohisa Yoshizawa

  • The patient health questionnaire, Japanese version: validity according to the mini-international neuropsychiatric interview-plus.

    Kumiko Muramatsu;Hitoshi Miyaoka;Kunitoshi Kamijima;Yoshiyuki Muramatsu

  • Kinetic analysis of amyloid fibril formation.

    Hironobu Naiki;Fumitake Gejyo

  • The Japanese Society of Hypertension Committee for Guidelines for the Management of Hypertension

    Toshio Ogihara;Kenjiro Kikuchi;Toshiro Fujita;Jitsuo Higaki

  • Successful Efavirenz Dose Reduction in HIV Type 1-Infected Individuals with Cytochrome P450 2B6 *6 and *26

    Hiroyuki Gatanaga;Tsunefusa Hayashida;Kiyoto Tsuchiya;Munehiro Yoshino

  • Establishment of a kinetic model of dialysis-related amyloid fibril extension in vitro

    Hironobu Naiki;Norikazu Hashimoto;Satoru Suzuki;Hideki Kimura

  • Uremic pruritus in chronic hemodialysis patients.

    Ichiei Narita;Seitaro Iguchi;Kentaro Omori;Fumitake Gejyo

  • Serum fibroblast growth factor-23 levels predict the future refractory hyperparathyroidism in dialysis patients

    Shohei Nakanishi;Junichiro James Kazama;Tomoko Nii-Kono;Kentaro Omori

  • Interaction between Aβ (1-42) and Aβ (1-40) in Alzheimer's β-amyloid fibril formation in vitro

    Kazuhiro Hasegawa;Itaru Yamaguchi;Saburou Omata;Fumitake Gejyo

  • Increased circulating levels of osteoclastogenesis inhibitory factor (osteoprotegerin) in patients with chronic renal failure.

    Junichiro J. Kazama;Takashi Shigematsu;Kazuki Yano;Eisuke Tsuda

  • Low Concentrations of Sodium Dodecyl Sulfate Induce the Extension of β2-Microglobulin-Related Amyloid Fibrils at a Neutral pH†

    Suguru Yamamoto;Kazuhiro Hasegawa;Itaru Yamaguchi;Shinobu Tsutsumi

  • Molecular Epidemiology of Respiratory Syncytial Virus Infections among Children with Acute Respiratory Symptoms in a Community over Three Seasons

    Mizuho Sato;Reiko Saito;Takatsugu Sakai;Yasuko Sano

  • Relationship between tonsils and IgA nephropathy as well as indications of tonsillectomy

    Yuansheng Xie;Xiangmei Chen;Xiangmei Chen;Shinichi Nishi;Shinichi Nishi;Ichiei Narita;Ichiei Narita

  • Glycosaminoglycans enhance the trifluoroethanol-induced extension of beta 2-microglobulin-related amyloid fibrils at a neutral pH.

    Suguru Yamamoto;Itaru Yamaguchi;Kazuhiro Hasegawa;Shinobu Tsutsumi

  • Effect of a Carbonaceous Oral Adsorbent on the Progression of CKD: A Multicenter, Randomized, Controlled Trial

    Tadao Akizawa;Yasushi Asano;Satoshi Morita;Takafumi Wakita

Frequent Co-Authors

Jun-ichi Miyazaki
Jun-ichi Miyazaki Osaka University
Hironobu Naiki
Hironobu Naiki University of Fukui
Masafumi Fukagawa
Masafumi Fukagawa Tokai University
Kazuo Suzuki
Kazuo Suzuki Teikyo University
Yasuhiko Tomino
Yasuhiko Tomino Juntendo University
Yuetsu Tanaka
Yuetsu Tanaka University of the Ryukyus
Yuji Goto
Yuji Goto Osaka University
Takao Saruta
Takao Saruta Keio University
Yoshiki Nishizawa
Yoshiki Nishizawa Osaka Metropolitan University

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