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Overview

Gennaro Esposito is affiliated with New York University Abu Dhabi in the United Arab Emirates. Their research spans multiple disciplines, with a primary focus on Medicine and Biochemistry, Genetics and Molecular Biology. These fields are complemented by subfields including Molecular Biology, Oncology, Physiology, Infectious Diseases, and Anesthesiology and Pain Medicine.

The main topics of Esposito's work cover a range of areas within biomedical research. Key areas include Protein Structure and Dynamics, Computational Drug Discovery Methods, Alzheimer's Disease Research and Treatments, Pain Management and Opioid Use, Cancer-related Molecular Pathways, Cancer Survivorship and Care, and Epigenetics and DNA Methylation.

Esposito has contributed to a variety of scientific publications, appearing frequently in several journals. The top venues include Physical Chemistry Chemical Physics, Molecules, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, and Cell Reports Physical Science. These publications reflect the interdisciplinary nature of their research.

Among their recent papers are:

  • Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function, 2021, Nature Communications
  • Designed Cell-Penetrating Peptide Inhibitors of Amyloid-beta Aggregation and Cytotoxicity, 2020, Cell Reports Physical Science
  • Careful Breakthrough Cancer Pain Treatment through Rapid-Onset Transmucosal Fentanyl Improves the Quality of Life in Cancer Patients: Results from the BEST Multicenter Study, 2020, Journal of Clinical Medicine
  • Satisfaction with Telemedicine for Cancer Pain Management: A Model of Care and Cross-Sectional Patient Satisfaction Study, 2022, Current Oncology
  • The Role of Anti-Nerve Growth Factor Monoclonal Antibodies in the Control of Chronic Cancer and Non-Cancer Pain, 2021, Journal of Pain Research

Frequent collaborators include Yamanappa Hunashal, Federico Fogolari, Arturo Cuomo, Marco Cascella, and Kristin C. Gunsalus, indicating ongoing teamwork in their research endeavors.

Best Publications

  • The solution structure of human β2-microglobulin reveals the prodromes of its amyloid transition

    Giuliana Verdone;Alessandra Corazza;Paolo Viglino;Fabio Pettirossi

  • Mouse Hsp25, a small heat shock protein

    Robyn A. Lindner;John A. Carver;Monika Ehrnsperger;Johannes Buchner

  • Size and shape of sodium deoxycholate micellar aggregates

    G. Esposito;E. Giglio;N. V. Pavel;A. Zanobi

  • High-Resolution 1H NMR Study of the Solution Structure of Alamethicin

    Gennaro Esposito;John A. Carver;Jonathan Boyd;Iain D. Campbell

  • Collagen Plays an Active Role in the Aggregation of β2-Microglobulin under Physiopathological Conditions of Dialysis-related Amyloidosis

    Annalisa Relini;Claudio Canale;Silvia De Stefano;Ranieri Rolandi

  • Biomolecular Electrostatics with the Linearized Poisson-Boltzmann Equation

    Federico Fogolari;Pierfrancesco Zuccato;Pierfrancesco Zuccato;Gennaro Esposito;Paolo Viglino

  • Effect of Tetracyclines on the Dynamics of Formation and Destructuration of β2-Microglobulin Amyloid Fibrils

    Sofia Giorgetti;Sara Raimondi;Katiuscia Pagano;Annalisa Relini

  • Physicochemical, bioactive and rheological properties of an exopolysaccharide produced by a probiotic Pediococcus pentosaceus M41.

    Mutamed Ayyash;Basim Abu-Jdayil;Amin Olaimat;Gennaro Esposito

  • Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function

    L. Palanikumar;Laura Karpauskaite;Mohamed Al-Sayegh;Ibrahim Chehade

  • Characterization, bioactivities, and rheological properties of exopolysaccharide produced by novel probiotic Lactobacillus plantarum C70 isolated from camel milk

    Mutamed Ayyash;Basim Abu-Jdayil;Pariyaporn Itsaranuwat;Emmanuel Galiwango

  • Probing protein structure by solvent perturbation of nuclear magnetic resonance spectra: Nuclear magnetic resonance spectral editing and topological mapping in proteins by paramagnetic relaxation filtering

    Gennaro Esposito;Arthur M. Lesk;Henriette Molinari;Andrea Motta

  • The Controlling Roles of Trp60 and Trp95 in β2-Microglobulin Function, Folding and Amyloid Aggregation Properties

    Gennaro Esposito;Stefano Ricagno;Alessandra Corazza;Enrico Rennella

  • Probing the Influence of Citrate-Capped Gold Nanoparticles on an Amyloidogenic Protein

    Giorgia Brancolini;Alessandra Corazza;Marco Vuano;Federico Fogolari

  • Structure, Folding Dynamics, and Amyloidogenesis of D76N β2-Microglobulin : ROLES OF SHEAR FLOW, HYDROPHOBIC SURFACES, AND α-CRYSTALLIN

    P. Patrizia Mangione;P. Patrizia Mangione;Gennaro Esposito;Annalisa Relini;Sara Raimondi

  • cGMP-binding prepares PKG for substrate binding by disclosing the C-terminal domain.

    Vera Alverdi;Hortense Mazon;Cees Versluis;Wieger Hemrika

  • Solution structure of regioselectively addressable functionalized templates: An NMR and restrained molecular dynamics investigation

    Pascal Dumy;Ian M. Eggleston;Gennaro Esposito;Stelian Nicula

  • An alternative method for distance evaluation from NOESY spectra

    Gennaro Esposito;Annalisa Pastore

  • 1H NMR SPECTROSCOPY REVEALS THAT MOUSE HSP25 HAS A FLEXIBLE C-TERMINAL EXTENSION OF 18 AMINO ACIDS

    John A. Carver;Gennaro Esposito;Gabriele Schwedersky;Matthias Gaestel

  • Carnosine Inhibits Aβ42 Aggregation by Perturbing the H‐Bond Network in and around the Central Hydrophobic Cluster

    Francesco Attanasio;Marino Convertino;Andrea Magno;Amedeo Caflisch

  • Properties of Some Variants of Human β2-Microglobulin and Amyloidogenesis

    Alessandra Corazza;Fabio Pettirossi;Paolo Viglino;Giuliana Verdone

Frequent Co-Authors

Vittorio Bellotti
Vittorio Bellotti University College London
Giuseppe Damante
Giuseppe Damante University of Udine
John A. Carver
John A. Carver Australian National University
Iain D. Campbell
Iain D. Campbell University of Oxford
Gianluca Tell
Gianluca Tell University of Udine
Martino Bolognesi
Martino Bolognesi University of Milan
Fabrizio Chiti
Fabrizio Chiti University of Florence
Franco Quadrifoglio
Franco Quadrifoglio University of Udine
Andrea Motta
Andrea Motta National Research Council (CNR)
Stefano Corni
Stefano Corni University of Padua

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