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Hironobu Naiki

Hironobu Naiki

D-Index & Metrics

Biology and Biochemistry

D-Index
76
Citations
20018
World Ranking
5064
National Ranking
331

Hironobu Naiki publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Hironobu Naiki sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 286 publications — 76th percentile

76% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Hironobu Naiki D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Hironobu Naiki sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 76 D-Index — 75th percentile

75% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Hironobu Naiki is affiliated with the University of Fukui in Japan. Their research focuses primarily on medical and biochemical fields, with significant contributions to the study and diagnosis of amyloidosis. Their work frequently appears in venues such as Pathology International, Amyloid, and Scientific Reports, reflecting a focused expertise in pathology and related biomedical sciences.

Naiki's publication record features key papers that address the pathology and clinical diagnosis of amyloidosis and related conditions. Notable papers include:

  • Human amyloidosis, still intractable but becoming curable: The essential role of pathological diagnosis in the selection of type-specific therapeutics (2020, Pathology International)
  • Steep increase in the number of transthyretin-positive cardiac biopsy cases in Japan: evidence obtained by the nation-wide pathology consultation for the typing diagnosis of amyloidosis (2023, Amyloid)

The scope of Naiki's research includes molecular biology and genetics, as well as clinical nephrology and rheumatology, indicating a multidisciplinary approach to understanding disease mechanisms and treatment outcomes. The main fields of study are:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

More specialized subfields cover:

  • Molecular Biology
  • Nephrology
  • Rheumatology
  • Genetics
  • Physiology

The major research topics explored involve amyloidosis diagnosis, treatment, and outcomes, with additional work on trace elements in health, Alzheimer's disease research, IgG4-related and inflammatory diseases, parathyroid disorders, drug transport, and dermatological and skeletal disorders. Main topics of Naiki's work include:

  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Trace Elements in Health
  • Alzheimer's disease research and treatments
  • IgG4-Related and Inflammatory Diseases
  • Parathyroid Disorders and Treatments
  • Drug Transport and Resistance Mechanisms
  • Dermatological and Skeletal Disorders

Collaboration is a notable aspect of Naiki's research activity. Frequent coauthors include:

  • Yoshiki Sekijima
  • Mitsuharu Ueda
  • Masayuki Iwano
  • Aina Yamaguchi
  • Naoki Takahashi

Common publication venues for Naiki's contributions are:

  • Pathology International
  • Amyloid
  • Scientific Reports
  • Neurobiology of Disease
  • Clinical Journal of Gastroenterology

The research output demonstrates a sustained focus on amyloidosis and related systemic diseases, combining pathological analysis with clinical and molecular approaches. Naiki's work features a combination of original research papers and collaborative studies that contribute to the understanding of complex diseases within the medical and biochemical realms.

Best Publications

  • Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T1.

    Hironobu Naiki;Keiichi Higuchi;Masanori Hosokawa;Toshio Takeda

  • Curcumin has potent anti-amyloidogenic effects for Alzheimer's β-amyloid fibrils in vitro

    Kenjiro Ono;Kazuhiro Hasegawa;Hironobu Naiki;Masahito Yamada

  • Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease

    Kenjiro Ono;Yuji Yoshiike;Akihiko Takashima;Kazuhiro Hasegawa

  • Direct observation of amyloid fibril growth monitored by thioflavin T fluorescence.

    Tadato Ban;Daizo Hamada;Kazuhiro Hasegawa;Hironobu Naiki

  • ThT 101: a primer on the use of thioflavin T to investigate amyloid formation

    Kirsten Gade Malmos;Luis M. Blancas-Mejia;Benedikt Weber;Johannes Buchner

  • A toxic monomeric conformer of the polyglutamine protein.

    Yoshitaka Nagai;Takashi Inui;Takashi Inui;Takashi Inui;H Akiko Popiel;Nobuhiro Fujikake

  • Mapping the core of the beta(2)-microglobulin amyloid fibril by H/D exchange.

    Masaru Hoshino;Hidenori Katou;Yoshihisa Hagihara;Yoshihisa Hagihara;Kazuhiro Hasegawa

  • Distinguishing crystal-like amyloid fibrils and glass-like amorphous aggregates from their kinetics of formation

    Yuichi Yoshimura;Yuxi Lin;Hisashi Yagi;Young-Ho Lee

  • First-order kinetic model of Alzheimer's beta-amyloid fibril extension in vitro.

    H Naiki;K Nakakuki

  • Iron (III) induces aggregation of hyperphosphorylated τ and its reduction to iron (II) reverses the aggregation: implications in the formation of neurofibrillary tangles of Alzheimer's disease

    Akira Yamamoto;Akira Yamamoto;Ryong Woon Shin;Kazuhiro Hasegawa;Hironobu Naiki

  • Iron (III) induces aggregation of hyperphosphorylated τ and its reduction to iron (II) reverses the aggregation: implications in the formation of neurofibrillary tangles of Alzheimer's disease: τ Aggregation by iron (III)

    Akira Yamamoto;Ryong-Woon Shin;Kazuhiro Hasegawa;Hironobu Naiki

  • Anti-amyloidogenic activity of tannic acid and its activity to destabilize Alzheimer's β-amyloid fibrils in vitro

    Kenjiro Ono;Kazuhiro Hasegawa;Hironobu Naiki;Masahito Yamada

  • A Seed for Alzheimer Amyloid in the Brain

    Hideki Hayashi;Nobuyuki Kimura;Haruyasu Yamaguchi;Kazuhiro Hasegawa

  • Establishment of a kinetic model of dialysis-related amyloid fibril extension in vitro

    Hironobu Naiki;Norikazu Hashimoto;Satoru Suzuki;Hideki Kimura

  • Direct observation of Aβ amyloid fibril growth and inhibition

    Tadato Ban;Masaru Hoshino;Satoshi Takahashi;Daizo Hamada

  • 3D structure of amyloid protofilaments of beta2-microglobulin fragment probed by solid-state NMR

    Kentaro Iwata;Toshimichi Fujiwara;Yoh Matsuki;Hideo Akutsu

  • Interaction between Aβ (1-42) and Aβ (1-40) in Alzheimer's β-amyloid fibril formation in vitro

    Kazuhiro Hasegawa;Itaru Yamaguchi;Saburou Omata;Fumitake Gejyo

  • Kinetic analysis of amyloid fibril polymerization in vitro.

    H Naiki;K Higuchi;K Nakakuki;T Takeda

  • Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2

    Josephine C. Ferreon;Chul Won Lee;Munehito Arai;Maria A. Martinez-Yamout

  • Presence of ras oncogene mutations and human papillomavirus DNA in human prostate carcinomas.

    Anwar K;Nakakuki K;Shiraishi T;Naiki H

Frequent Co-Authors

Yuji Goto
Yuji Goto Osaka University
Masahito Yamada
Masahito Yamada Kanazawa University
Keiichi Higuchi
Keiichi Higuchi Shinshu University
Fumitake Gejyo
Fumitake Gejyo Niigata University
Toshio Takeda
Toshio Takeda Kyoto University
Masanori Hosokawa
Masanori Hosokawa Kyoto University
Tomoji Kawai
Tomoji Kawai Osaka University
Satoshi Takahashi
Satoshi Takahashi Tohoku University
Katsumi Matsuzaki
Katsumi Matsuzaki Kyoto University
Akihiko Takashima
Akihiko Takashima Gakushuin University

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