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Akihiko Takashima

Akihiko Takashima

Gakushuin University
Japan

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Biology and Biochemistry 77 4804 4430 313 293 242 20226

Akihiko Takashima publications per year

The chart shows the history of publications by Akihiko Takashima between 1984 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Akihiko Takashima published across 42 years, from 1984 to 2025, averaging 6.5 papers a year. Output peaked at 18 publications in 2004. 9 of the 271 publications appeared in the last two years.

No. of publications
5 10 15
Bar chart. Horizontal axis: year, 1984 to 2025. Vertical axis: number of publications, 0 to 18. Peak 18 publications in 2004. 1984: 1 publication 1985: 2 publications 1986: 1 publication 1987: 1 publication 1988: 0 publications 1989: 1 publication 1990: 0 publications 1991: 0 publications 1992: 0 publications 1993: 3 publications 1994: 0 publications 1995: 5 publications 1996: 10 publications 1997: 6 publications 1998: 5 publications 1999: 5 publications 2000: 5 publications 2001: 6 publications 2002: 12 publications 2003: 11 publications 2004: 18 publications 2005: 5 publications 2006: 13 publications 2007: 15 publications 2008: 14 publications 2009: 11 publications 2010: 9 publications 2011: 11 publications 2012: 7 publications 2013: 7 publications 2014: 7 publications 2015: 4 publications 2016: 7 publications 2017: 12 publications 2018: 7 publications 2019: 13 publications 2020: 7 publications 2021: 8 publications 2022: 8 publications 2023: 5 publications 2024: 7 publications 2025: 2 publications
1984 2025

271 publications in total across all disciplines

View publications per year as a table
Akihiko Takashima: publications per year, 1984 to 2025
Year Publications
1984 1
1985 2
1986 1
1987 1
1988 0
1989 1
1990 0
1991 0
1992 0
1993 3
1994 0
1995 5
1996 10
1997 6
1998 5
1999 5
2000 5
2001 6
2002 12
2003 11
2004 18
2005 5
2006 13
2007 15
2008 14
2009 11
2010 9
2011 11
2012 7
2013 7
2014 7
2015 4
2016 7
2017 12
2018 7
2019 13
2020 7
2021 8
2022 8
2023 5
2024 7
2025 2
Total 271
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Akihiko Takashima publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Akihiko Takashima sits on this spectrum.

No. of scientists
200 400 600 800
Bar chart with 100 bars. Horizontal axis: publications, 47–56 to 1,028+. Vertical axis: number of scientists, 0 to 980. Most scientists, 980, have 127–136 publications. The last bar groups every scientist with 1,028 publications or more. The highlighted bar, 237–246 publications, is where this scientist sits. 47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientist 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientist 1,028+ publications: 100 scientists
47–56 publications 1,028+

This scientist: 242 publications — 65th percentile

65% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

View publications distribution as a table
Number of Biology and Biochemistry scientists by publication count, Research.com 2026 ranking edition. Based on 19,587 ranked scientists.
Publications Scientists This scientist
47–56 8
57–66 35
67–76 106
77–86 231
87–96 413
97–106 546
107–116 704
117–126 848
127–136 980
137–146 942
147–156 969
157–166 949
167–176 951
177–186 915
187–196 787
197–206 840
207–216 733
217–226 708
227–236 651
237–246 605 242
247–256 510
257–266 524
267–276 434
277–286 417
287–296 350
297–306 363
307–316 315
317–326 296
327–336 261
337–346 240
347–356 219
357–366 196
367–376 154
377–386 161
387–396 155
397–406 145
407–416 124
417–426 112
427–436 132
437–446 116
447–456 99
457–466 81
467–476 91
477–486 80
487–496 80
497–506 59
507–516 36
517–526 46
527–536 54
537–546 44
547–556 43
557–566 43
567–576 42
577–586 25
587–596 34
597–606 23
607–616 33
617–626 31
627–636 27
637–646 25
647–656 28
657–666 34
667–676 18
677–686 16
687–696 10
697–706 12
707–716 21
717–726 12
727–736 12
737–746 10
747–756 7
757–766 13
767–776 15
777–786 13
787–796 9
797–806 9
807–816 7
817–826 4
827–836 9
837–846 7
847–856 3
857–866 5
867–876 5
877–886 11
887–896 3
897–906 4
907–916 7
917–926 5
927–936 6
937–946 6
947–956 3
957–966 7
967–976 2
977–986 2
987–996 1
997–1,006 5
1,007–1,016 2
1,017–1,026 2
1,027 1
1,028+ 100
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Akihiko Takashima D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Akihiko Takashima sits on this spectrum.

No. of scientists
250 500 750 1,000 1,250
Bar chart with 65 bars. Horizontal axis: D-Index, 40–41 to 167+. Vertical axis: number of scientists, 0 to 1,253. Most scientists, 1,253, have 58–59 D-Index. The last bar groups every scientist with 167 D-Index or more. The highlighted bar, 76–77 D-Index, is where this scientist sits. 40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40–41 D-Index 167+

This scientist: 77 D-Index — 76th percentile

76% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

View D-Index distribution as a table
Number of Biology and Biochemistry scientists by D-index, Research.com 2026 ranking edition. Based on 19,587 ranked scientists.
D-Index Scientists This scientist
40–41 80
42–43 183
44–45 316
46–47 504
48–49 718
50–51 899
52–53 1,025
54–55 1,149
56–57 1,235
58–59 1,253
60–61 1,162
62–63 1,130
64–65 1,031
66–67 897
68–69 814
70–71 714
72–73 709
74–75 596
76–77 512 77
78–79 473
80–81 412
82–83 373
84–85 358
86–87 285
88–89 273
90–91 227
92–93 208
94–95 193
96–97 153
98–99 157
100–101 148
102–103 120
104–105 113
106–107 100
108–109 86
110–111 67
112–113 71
114–115 73
116–117 64
118–119 53
120–121 60
122–123 54
124–125 43
126–127 38
128–129 49
130–131 26
132–133 18
134–135 23
136–137 32
138–139 32
140–141 27
142–143 19
144–145 22
146–147 12
148–149 16
150–151 14
152–153 10
154–155 13
156–157 10
158–159 7
160–161 9
162–163 13
164–165 4
166 4
167+ 98
Download as CSV

Overview

Akihiko Takashima is affiliated with Gakushuin University in Japan and conducts research primarily in the fields of Medicine and Neuroscience. Their work covers multiple subfields including Physiology, Cellular and Molecular Neuroscience, Molecular Biology, Neurology, and Cognitive Neuroscience.

The scientist's research focuses on topics related to Alzheimer's disease research and treatments, dementia and cognitive impairment research, memory and neural mechanisms, neuroscience and neuropharmacology research, neuroinflammation and neurodegeneration mechanisms, protein hydrolysis and bioactive peptides, and biochemical effects in animals.

Takashima's recent publications illustrate their contributions to neurodegenerative disease studies and molecular mechanisms associated with tau protein and cognitive decline. Notable papers include:

  • New Insights Into Drug Discovery Targeting Tau Protein, 2020, Frontiers in Molecular Neuroscience
  • Disulfide bond formation in microtubule-associated tau protein promotes tau accumulation and toxicity in vivo, 2021, Human Molecular Genetics
  • β-Lactolin, a Whey-Derived Lacto-Tetrapeptide, Prevents Alzheimer's Disease Pathologies and Cognitive Decline, 2020, Journal of Alzheimer s Disease
  • Amyloid β and tau pathology in brains of aged pinniped species (sea lion, seal, and walrus), 2021, Acta Neuropathologica Communications
  • Phosphorylation and oligomerization of α-synuclein associated with GSK-3β activation in the rTg4510 mouse model of tauopathy, 2020, Acta Neuropathologica Communications

Frequent co-authors who have collaborated extensively with Takashima include:

  • Yoshiyuki Soeda
  • Riki Koike
  • Yuta Takaichi
  • Hiroyuki Nakayama
  • Yasuhisa Ano

The researcher's work has been published multiple times in venues such as bioRxiv (Cold Spring Harbor Laboratory), Acta Neuropathologica Communications, Journal of Alzheimer s Disease, Communications Biology, and Scientific Reports.

Best Publications

  • Imaging of Tau Pathology in a Tauopathy Mouse Model and in Alzheimer Patients Compared to Normal Controls

    Masahiro Maruyama;Hitoshi Shimada;Tetsuya Suhara;Hitoshi Shinotoh

  • Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease

    Kenjiro Ono;Yuji Yoshiike;Akihiko Takashima;Kazuhiro Hasegawa

  • Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

    Taiichi Katayama;Kazunori Imaizumi;Naoya Sato;Ko Miyoshi

  • Tau protein kinase I is essential for amyloid beta-protein-induced neurotoxicity.

    Akihiko Takashima;Kaori Noguchi;Kazuki Sato;Toshimitsu Hoshino

  • A CBP Binding Transcriptional Repressor Produced by the PS1/ϵ-Cleavage of N-Cadherin Is Inhibited by PS1 FAD Mutations

    Philippe Marambaud;Paul H Wen;Anindita Dutt;Junichi Shioi

  • Chaperones increase association of tau protein with microtubules

    Fei Dou;William J. Netzer;Kentaro Tanemura;Feng Li

  • Presenilin 1 associates with glycogen synthase kinase-3β and its substrate tau

    Akihiko Takashima;Miyuki Murayama;Ohoshi Murayama;Toshiyuki Kohno

  • GSK-3 is essential in the pathogenesis of Alzheimer's disease.

    Akihiko Takashima

  • Activation of tau protein kinase I/glycogen synthase kinase-3β by amyloid β peptide (25–35) enhances phosphorylation of tau in hippocampal neurons

    Akihiko Takashima;Toshiyuki Honda;Kaori Yasutake;Gilles Michel

  • Regulation of mitochondrial pyruvate dehydrogenase activity by tau protein kinase I/glycogen synthase kinase 3beta in brain

    Minako Hoshi;Akihiko Takashima;Kaori Noguchi;Miyuki Murayama

  • Exposure of rat hippocampal neurons to amyloid β peptide (25–35) induces the inactivation of phosphatidyl inositol-3 kinase and the activation of tau protein kinase I/glycogen synthase kinase-3β

    Akihiko Takashima;Kaori Noguchi;Gilles Michel;Marc Mercken

  • Granular tau oligomers as intermediates of tau filaments.

    Sumihiro Maeda;Naruhiko Sahara;Yuko Saito;Miyuki Murayama

  • Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3 beta and cyclin-dependent kinase 5, a component of TPK II

    Haruyasu Yamaguchi;Koichi Ishiguro;Tsuneko Uchida;Akihiko Takashima

  • Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau

    Yoshitaka Tatebayashi;Tomohiro Miyasaka;De-Hua Chui;Takumi Akagi

  • Alterations in Glucose Metabolism Induce Hypothermia Leading to Tau Hyperphosphorylation through Differential Inhibition of Kinase and Phosphatase Activities: Implications for Alzheimer's Disease

    Emmanuel Planel;Tomohiro Miyasaka;Thomas Launey;De Hua Chui

  • Microtubule-associated protein tau is essential for long-term depression in the hippocampus

    Tetsuya Kimura;Daniel J. Whitcomb;Jihoon Jo;Philip Regan

  • Increased levels of granular tau oligomers: an early sign of brain aging and Alzheimer's disease.

    Sumihiro Maeda;Naruhiko Sahara;Yuko Saito;Shigeo Murayama

  • Insulin Dysfunction Induces In Vivo Tau Hyperphosphorylation through Distinct Mechanisms

    Emmanuel Planel;Yoshitaka Tatebayashi;Tomohiro Miyasaka;Li Liu

  • New Insights on How Metals Disrupt Amyloid β-Aggregation and Their Effects on Amyloid-β Cytotoxicity *

    Yuji Yoshiike;Kentaro Tanemura;Ohoshi Murayama;Takumi Akagi

  • Neurodegeneration with Tau Accumulation in a Transgenic Mouse Expressing V337M Human Tau

    Kentaro Tanemura;Miyuki Murayama;Takumi Akagi;Tsutomu Hashikawa

Frequent Co-Authors

Koichi Ishiguro
Koichi Ishiguro Juntendo University
Tsutomu Hashikawa
Tsutomu Hashikawa RIKEN Center for Brain Science
Nuno Sousa
Nuno Sousa Centro Universitario Max Planck
Yasuo Ihara
Yasuo Ihara Doshisha University
Masahito Yamada
Masahito Yamada Kanazawa University
Osborne F. X. Almeida
Osborne F. X. Almeida Max Planck Institute of Psychiatry
Takaomi C. Saido
Takaomi C. Saido RIKEN Center for Brain Science
Benjamin Wolozin
Benjamin Wolozin Boston University
Makoto Higuchi
Makoto Higuchi National Institutes for Quantum and Radiological Science and Technology
Hideyuki Okano
Hideyuki Okano Keio University

External Links

Personal website of Akihiko Takashima

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Best Scientists Citing Akihiko Takashima

Jesús Avila

Jesús Avila

Centro de Biología Molecular Severo Ochoa

Publications: 85

Makoto Higuchi

Makoto Higuchi

National Institutes for Quantum and Radiological Science and Technology

Publications: 66

Jian-Zhi Wang

Jian-Zhi Wang

Huazhong University of Science and Technology

Publications: 52

Luc Buée

Luc Buée

University of Lille

Publications: 49

Virginia M.-Y. Lee

Virginia M.-Y. Lee

University of Pennsylvania

Publications: 46

John Q. Trojanowski

John Q. Trojanowski

University of Pennsylvania

Publications: 45

Tetsuya Suhara

Tetsuya Suhara

National Institutes for Quantum and Radiological Science and Technology

Publications: 44

Masaya Tohyama

Masaya Tohyama

Kindai University

Publications: 41

Rakez Kayed

Rakez Kayed

The University of Texas Medical Branch at Galveston

Publications: 40

Nobuyuki Okamura

Nobuyuki Okamura

Tohoku Medical and Pharmaceutical University

Publications: 36

Masahito Yamada

Masahito Yamada

Kanazawa University

Publications: 35

Nibaldo C. Inestrosa

Nibaldo C. Inestrosa

Pontificia Universidad Católica de Chile

Publications: 34

Fei Liu

Fei Liu

New York State Office for People With Developmental Disabilities

Publications: 33

Cheng-Xin Gong

Cheng-Xin Gong

City University of New York

Publications: 33

Bradley T. Hyman

Bradley T. Hyman

Harvard University

Publications: 32

Chad A. Dickey

Chad A. Dickey

University of South Florida

Publications: 31

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