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Masaya Tohyama

Masaya Tohyama

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Medicine
Japan
2023

D-Index & Metrics

Medicine

D-Index
122
Citations
53237
World Ranking
3488
National Ranking
67

Research.com Recognitions

  • 2023 - Research.com Medicine in Japan Leader Award

Overview

Masaya Tohyama is affiliated with Kindai University in Japan and contributes to the fields of Neuroscience as well as Biochemistry, Genetics and Molecular Biology. Their research spans several subfields including Molecular Biology, Behavioral Neuroscience, Biological Psychiatry, Neurology, and Endocrinology, Diabetes and Metabolism.

Their recent scholarly output includes studies published in Developmental Neurobiology, Frontiers in Aging Neuroscience, and Cureus. Notable papers feature topics related to brain development, inflammation, stress, and pharmacological effects of natural compounds.

  • Coactivator-associated arginine methyltransferase 1 controls oligodendrocyte differentiation in the corpus callosum during early brain development, 2022, Developmental Neurobiology
  • Involvement of inflammatory responses in the brain to the onset of major depressive disorder due to stress exposure, 2022, Frontiers in Aging Neuroscience
  • Kamishoyosan Normalizes Dendritic Spine Morphology in the Medial Prefrontal Cortex by Regulating microRNA-18 and Glucocorticoid Receptor Expressions in Postmenopausal Chronic Stress-Exposed Mice, 2024, Cureus

Their research addresses a range of scientific topics such as Stress Responses and Cortisol, Cancer-related gene regulation, Epigenetics and DNA Methylation, Tryptophan and brain disorders, Neuroinflammation and Neurodegeneration Mechanisms, Menopause: Health Impacts and Treatments, and Pharmacological Effects of Natural Compounds.

  • Stress Responses and Cortisol
  • Cancer-related gene regulation
  • Epigenetics and DNA Methylation
  • Tryptophan and brain disorders
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Menopause: Health Impacts and Treatments
  • Pharmacological Effects of Natural Compounds

Masaya Tohyama has collaborated frequently with researchers including Yugo Ishino, Shoko Shimizu, Shingo Miyata, Yoshihisa Koyama, and Takashi Takeda. Collaboration has focused on topics intersecting molecular mechanisms of brain function, stress-related disorders, and the neurobiology of aging.

  • Yugo Ishino
  • Shoko Shimizu
  • Shingo Miyata
  • Yoshihisa Koyama
  • Takashi Takeda

The diversity of their contributions is reflected in the variety of publication venues, which indicate a cross-disciplinary engagement spanning developmental neurobiology, aging neuroscience, and clinical pharmacology.

Best Publications

  • Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress.

    Takunari Yoneda;Kazunori Imaizumi;Kayoko Oono;Daishi Yui

  • Distribution of the histaminergic neuron system in the central nervous system of rats; a fluorescent immunohistochemical analysis with histidine decarboxylase as a marker.

    Takehiko Watanabe;Yoshitaka Taguchi;Sadao Shiosaka;Junya Tanaka

  • Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Aβ-induced cell death

    Junichi Hitomi;Junichi Hitomi;Taiichi Katayama;Taiichi Katayama;Yutaka Eguchi;Yutaka Eguchi;Takashi Kudo

  • An arcuato-paraventricular and -dorsomedial hypothalamic neuropeptide Y-containing system which lacks noradrenaline in the rat.

    F.L. Bai;M. Yamano;Y. Shiotani;P.C. Emson

  • Tumor Necrosis Factor Induces Bcl-2 and Bcl-x Expression through NFκB Activation in Primary Hippocampal Neurons

    Michio Tamatani;Yong Ho Che;Hideo Matsuzaki;Satoshi Ogawa

  • The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI.

    Toshihide Yamashita;Masaya Tohyama

  • Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

    Taiichi Katayama;Kazunori Imaizumi;Naoya Sato;Ko Miyoshi

  • Distribution of calcitonin gene-related peptide in the rat peripheral nervous system with reference to its coexistence with substance P.

    Y. Lee;K. Takami;Y. Kawai;S. Girgis

  • The p75 receptor transduces the signal from myelin-associated glycoprotein to Rho

    Toshihide Yamashita;Haruhisa Higuchi;Masaya Tohyama

  • An intracellular protein that binds amyloid-β peptide and mediates neurotoxicity in Alzheimer's disease

    Shi Du Yan;Jin Fu;Claudio Soto;Xi Chen

  • Induction of aquaporin-4 water channel mRNA after focal cerebral ischemia in rat.

    Masaaki Taniguchi;Toshihide Yamashita;Eiji Kumura;Michio Tamatani

  • Topographic localization of calcitonin gene-related peptide in the rat brain: An immunohistochemical analysis

    Y. Kawai;K. Takami;S. Shiosaka;P.C. Emson

  • Disrupted-In-Schizophrenia 1 , a candidate gene for schizophrenia, participates in neurite outgrowth

    K Miyoshi;A Honda;K Baba;M Taniguchi

  • Coexistence of calcitonin gene-related peptide and substance P-like peptide in single cells of the trigeminal ganglion of the rat: immunohistochemical analysis.

    Y. Lee;Y. Kawai;S. Shiosaka;K. Takami

  • Induction of neuronal death by ER stress in Alzheimer's disease.

    Taiichi Katayama;Kazunori Imaizumi;Takayuki Manabe;Junichi Hitomi

  • Apoptosis induced by endoplasmic reticulum stress depends on activation of caspase-3 via caspase-12.

    Junichi Hitomi;Taiichi Katayama;Manabu Taniguchi;Akiko Honda

  • The differential expression patterns of messenger RNAs encoding non-N-methyl-d-aspartate glutamate receptor subunits (GluR1–4) in the rat brain

    K. Sato;H. Kiyama;M. Tohyama

  • Stress-induced c-fos expression in the rat brain: activation mechanism of sympathetic pathway.

    Emiko Senba;Keiji Matsunaga;Masaya Tohyama;Koichi Noguchi

  • Spinal projections from the lower brain stem in the cat as demonstrated by the horseradish peroxidase technique. I. Origins of the reticulospinal tracts and their funicular trajectories

    Masaya Tohyama;Kazuya Sakai;Denise Salvert;Monique Touret

  • Ontogeny of substance P-containing neuron system of the rat: immunohistochemical analysis--I. Forebrain and upper brain stem.

    S. Inagaki;M. Sakanaka;S. Shiosaka;E. Senba

Frequent Co-Authors

Hiroshi Kiyama
Hiroshi Kiyama Nagoya University
Sadao Shiosaka
Sadao Shiosaka Osaka University
Emiko Senba
Emiko Senba Osaka University
Taiichi Katayama
Taiichi Katayama Osaka University
Shinobu Inagaki
Shinobu Inagaki Osaka University
Akio Wanaka
Akio Wanaka Nara Medical University
Masahiro Sakanaka
Masahiro Sakanaka Ehime University
Makoto Sato
Makoto Sato University of Fukui
Toshihide Yamashita
Toshihide Yamashita Osaka University
Kazunori Imaizumi
Kazunori Imaizumi Hiroshima University

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