2026 Clifford B. Saper: Neuroscience Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Neuroscience	158	118	105	79	69	480	102531
Medicine	158	845	775	481	430	477	102506

Research.com Recognitions

2026 - Research.com Neuroscience in United States Leader Award
2025 - Research.com Neuroscience in United States Leader Award
2009 - Member of the National Academy of Medicine (NAM)
2003 - Fellow of the American Association for the Advancement of Science (AAAS)
Member of the Association of American Physicians
Member of the Association of American Physicians
Member of the Association of American Physicians
Member of the Association of American Physicians

Overview

Clifford B. Saper is affiliated with the Beth Israel Deaconess Medical Center in the United States. Their research primarily focuses on neuroscience and medicine, with a substantial body of work across several related subfields.

Their main fields of study include:

Neuroscience
Medicine

Within these, more specific subfields of investigation include:

Endocrine and Autonomic Systems
Cognitive Neuroscience
Physiology
Experimental and Cognitive Psychology
Neurology

The research topics covered by their publications illustrate interests in:

Circadian rhythm and melatonin
Sleep and Wakefulness Research
Neuroscience of respiration and sleep
Sleep and related disorders
Neuroendocrine regulation and behavior
Adipose Tissue and Metabolism
Single-cell and spatial transcriptomics

Prominent venues where Clifford B. Saper has published multiple papers include:

Annals of Neurology
SLEEP
Nature Communications
Zenodo (CERN European Organization for Nuclear Research)
Journal of Neuroscience

Selected recent papers and their publication years and venues are:

Orexin neurons inhibit sleep to promote arousal, 2022, Nature Communications
EP3R-Expressing Glutamatergic Preoptic Neurons Mediate Inflammatory Fever, 2020, Journal of Neuroscience
Role of serotonergic dorsal raphe neurons in hypercapnia-induced arousals, 2020, Nature Communications
Median preoptic GABA and glutamate neurons exert differential control over sleep behavior, 2022, Current Biology
Hypothalamic Hamartomas, 2021, Neurology

Collaborations are a significant component of this scientist's work. Frequent coauthors include:

Natalia Machado
Sathyajit S. Bandaru
Roberto De Luca
Elda Arrigoni
Satvinder Kaur

Recognized honors include:

Member of the National Academy of Medicine (NAM), 2009
Fellow of the American Association for the Advancement of Science (AAAS), 2003
Member of the Association of American Physicians

Best Publications

Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation

Richard M. Chemelli;Jon T. Willie;Christopher M. Sinton;Joel K. Elmquist

3630
Citations
Hypothalamic regulation of sleep and circadian rhythms

Clifford B. Saper;Thomas E. Scammell;Jun Lu

3251
Citations
The sleep switch: hypothalamic control of sleep and wakefulness

Clifford B Saper;Thomas C Chou;Thomas E Scammell

2036
Citations
Differential expression of orexin receptors 1 and 2 in the rat brain.

Jacob N. Marcus;Carl J. Aschkenasi;Charlotte E. Lee;Richard M. Chemelli

1860
Citations
Sleep State Switching

Clifford B. Saper;Patrick M. Fuller;Nigel P. Pedersen;Jun Lu

1524
Citations
From lesions to leptin: hypothalamic control of food intake and body weight.

Joel K Elmquist;Carol Fuzeti Elias;Clifford B Saper

1522
Citations
The need to feed: Homeostatic and hedonic control of eating

Clifford B. Saper;Thomas C. Chou;Joel K. Elmquist

1490
Citations
Direct hypothalamo-autonomic connections.

C.B. Saper;A.D. Loewy;L.W. Swanson;W.M. Cowan

1396
Citations
Efferent connections of the parabrachial nucleus in the rat.

C.B. Saper;C.B. Saper;A.D. Loewy;A.D. Loewy

1388
Citations
Distributions of leptin receptor mRNA isoforms in the rat brain.

Joel K. Elmquist;Christian Bjørbæk;Rexford S. Ahima;Jeffrey S. Flier

1342
Citations
A putative flip–flop switch for control of REM sleep

Jun Lu;David Sherman;Marshall Devor;Marshall Devor;Clifford B. Saper

1312
Citations
Activation of Ventrolateral Preoptic Neurons During Sleep

J. E. Sherin;P. J. Shiromani;R. W. McCarley;C. B. Saper

1267
Citations
Expression of ghrelin receptor mRNA in the rat and the mouse brain.

Jeffrey M. Zigman;Juli E. Jones;Charlotte E. Lee;Clifford B. Saper

1217
Citations
The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects.

Laura E. Nelson;Jun Lu;Tianzhi Guo;Clifford B. Saper

1198
Citations
Subnuclear organization of the efferent connections of the parabrachial nucleus in the rat.

Carl E. Fulwiler;Clifford B. Saper

1183
Citations
Efferent projections of the infralimbic cortex of the rat.

Karen M. Hurley;Horst Herbert;Margaret M. Moga;Clifford B. Saper

1129
Citations
Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease

B. F. Boeve;M. H. Silber;C. B. Saper;T. J. Ferman

1125
Citations
Leptin Differentially Regulates NPY and POMC Neurons Projecting to the Lateral Hypothalamic Area

Carol F Elias;Carl Aschkenasi;Charlotte Lee;Joseph Kelly

1111
Citations
Cortical projections arising from the basal forebrain: a study of cholinergic and noncholinergic components employing combined retrograde tracing and immunohistochemical localization of choline acetyltransferase.

D.B. Rye;B.H. Wainer;M.-M. Mesulam;E.J. Mufson

1108
Citations
Connections of the parabrachial nucleus with the nucleus of the solitary tract and the medullary reticular formation in the rat.

Horst Herbert;Margaret M. Moga;Clifford B. Saper

1102
Citations
Interleukin-1 immunoreactive innervation of the human hypothalamus

Christopher D. Breder;Charles A. Dinarello;Clifford B. Saper

1091
Citations

Frequent Co-Authors

Thomas E. Scammell Harvard Medical School

Joel K. Elmquist The University of Texas Southwestern Medical Center

Jun Lu Zhejiang University

Patrick M. Fuller Beth Israel Deaconess Medical Center

Elda Arrigoni Harvard Medical School

Nicholas D. Schiff Cornell University

John H. R. Maunsell University of Chicago

Joshua J. Gooley Duke NUS Graduate Medical School

Michael Lazarus University of Tsukuba

External Links

Personal website of Clifford B. Saper Google Scholar page

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