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Zhi-Li Huang

Zhi-Li Huang

D-Index & Metrics

Neuroscience

D-Index
54
Citations
11032
World Ranking
4907
National Ranking
69

Overview

Zhi-Li Huang is affiliated with Fudan University in China and has contributed extensively to the field of neuroscience, with a particular focus on sleep and wakefulness, circadian rhythms, and neuropharmacology. Their research emphasis aligns with several subfields including cognitive neuroscience, endocrine and autonomic systems, and molecular biology, reflecting a multidisciplinary approach to understanding brain function and behavior.

The main research topics covered by Huang's work include:

  • Sleep and Wakefulness Research
  • Circadian rhythm and melatonin
  • Sleep and related disorders
  • Neuroscience and Neuropharmacology Research
  • Neuroscience of respiration and sleep
  • Anesthesia and Neurotoxicity Research
  • Neural dynamics and brain function

Huang has published numerous papers in prominent scientific venues. Frequent publication outlets include:

  • Frontiers in Neuroscience
  • Nature Communications
  • Brain Sciences
  • British Journal of Pharmacology
  • bioRxiv (Cold Spring Harbor Laboratory)

Selected recent papers by Huang illustrate their contribution to understanding neural mechanisms associated with sleep, anesthesia, and memory:

  • "Hypothalamic modulation of adult hippocampal neurogenesis in mice confers activity-dependent regulation of memory and anxiety-like behavior," 2022, Nature Neuroscience
  • "Ventral pallidal GABAergic neurons control wakefulness associated with motivation through the ventral tegmental pathway," 2020, Molecular Psychiatry
  • "Nucleus accumbens neurons expressing dopamine D1 receptors modulate states of consciousness in sevoflurane anesthesia," 2021, Current Biology
  • "Propagated α-synucleinopathy recapitulates REM sleep behaviour disorder followed by parkinsonian phenotypes in mice," 2020, Brain
  • "Understanding the Neural Mechanisms of General Anesthesia from Interaction with Sleep-Wake State: A Decade of Discovery," 2023, Pharmacological Reviews

Frequent collaborators in Huang's research include Wei-Min Qu, Ze-Ka Chen, Michael Lazarus, Wei Xu, and Shan Jiang. These coauthors have often contributed to studies that intersect with neural mechanisms regulating sleep, motivation, and anesthesia.

Within the broader scientific community, Huang's work is situated primarily in neuroscience, having published over 160 papers within this field. The scientist's specific engagement with cognitive neuroscience and the endocrine and autonomic systems underscores a focus on how neural processes integrate with physiological states to influence behavior and consciousness.

Best Publications

  • Arousal effect of orexin A depends on activation of the histaminergic system

    Zhi-Li Huang;Wei-Min Qu;Wei-Dong Li;Takatoshi Mochizuki

  • Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine

    Zhi-Li Huang;Wei-Min Qu;Naomi Eguchi;Jiang-Fan Chen

  • Arousal Effect of Caffeine Depends on Adenosine A2A Receptors in the Shell of the Nucleus Accumbens

    Michael Lazarus;Hai Ying Shen;Yoan Cherasse;Wei Min Qu

  • Dopaminergic D1 and D2 Receptors Are Essential for the Arousal Effect of Modafinil

    Wei-Min Qu;Zhi-Li Huang;Xin-Hong Xu;Naomi Matsumoto

  • Prostaglandins and adenosine in the regulation of sleep and wakefulness

    Zhi-Li Huang;Yoshihiro Urade;Osamu Hayaishi

  • The Role of Adenosine in the Regulation of Sleep

    Zhi-Li Huang;Yoshihiro Urade;Osamu Hayaishi

  • Altered sleep–wake characteristics and lack of arousal response to H3 receptor antagonist in histamine H1 receptor knockout mice

    Zhi-Li Huang;Takatoshi Mochizuki;Wei-Min Qu;Zong-Yuan Hong

  • Essential Role of Dopamine D2 Receptor in the Maintenance of Wakefulness, But Not in Homeostatic Regulation of Sleep, in Mice

    Wei-Min Qu;Xin-Hong Xu;Ming-Ming Yan;Yi-Qun Wang

  • Nucleus accumbens controls wakefulness by a subpopulation of neurons expressing dopamine D 1 receptors

    Yan-Jia Luo;Ya-Dong Li;Lu Wang;Su-Rong Yang

  • Curcumin exerts antinociceptive effects in a mouse model of neuropathic pain: descending monoamine system and opioid receptors are differentially involved.

    Xin Zhao;Ying Xu;Qing Zhao;Chang-Rui Chen

  • Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice.

    Yo Oishi;Qi Xu;Qi Xu;Lucun Wang;Bin Jia Zhang

  • Dominant localization of prostaglandin D receptors on arachnoid trabecular cells in mouse basal forebrain and their involvement in the regulation of non-rapid eye movement sleep

    Akira Mizoguchi;Naomi Eguchi;Kazushi Kimura;Yoshimoto Kiyohara

  • Lipocalin-type prostaglandin D synthase produces prostaglandin D2 involved in regulation of physiological sleep

    Wei Min Qu;Zhi Li Huang;Zhi Li Huang;Xin Hong Xu;Xin Hong Xu;Kosuke Aritake

  • Sleep regulation in adenosine A2A receptor-deficient mice.

    Yoshihiro Urade;Naomi Eguchi;Wei-Min Qu;Mie Sakata

  • Adenosine A2A receptors in ventral striatum, hypothalamus and nociceptive circuitry Implications for drug addiction, sleep and pain

    S. Ferré;I. Diamond;S.R. Goldberg;L. Yao

  • Lipocalin-type prostaglandin D synthase/β-trace is a major amyloid β-chaperone in human cerebrospinal fluid

    Takahisa Kanekiyo;Tadato Ban;Kosuke Aritake;Zhi Li Huang;Zhi Li Huang

  • Adenosine in the tuberomammillary nucleus inhibits the histaminergic system via A1 receptors and promotes non-rapid eye movement sleep

    Yo Oishi;Zhi-Li Huang;Bertil B. Fredholm;Yoshihiro Urade

  • Roles of adenosine and its receptors in sleep-wake regulation.

    Zhi-Li Huang;Ze Zhang;Wei-Min Qu

  • An adenosine A2A receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats

    Zong-Yuan Hong;Zong-Yuan Hong;Zhi-Li Huang;Zhi-Li Huang;Wei-Min Qu;Naomi Eguchi

  • Role of the basal ganglia in the control of sleep and wakefulness

    Michael Lazarus;Jiang-Fan Chen;Yoshihiro Urade;Yoshihiro Urade;Zhi-Li Huang;Zhi-Li Huang

Frequent Co-Authors

Michael Lazarus
Michael Lazarus University of Tsukuba
Takatoshi Mochizuki
Takatoshi Mochizuki Beth Israel Deaconess Medical Center
Jiang-Fan Chen
Jiang-Fan Chen Boston University
Jun Lu
Jun Lu Zhejiang University
Serge N. Schiffmann
Serge N. Schiffmann Université Libre de Bruxelles
Yu-Qiang Ding
Yu-Qiang Ding Fudan University
Gal Richter-Levin
Gal Richter-Levin University of Haifa
Detlev Boison
Detlev Boison Rutgers, The State University of New Jersey
Sergi Ferré
Sergi Ferré National Institute on Drug Abuse

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