Seiji Nishino mainly focuses on Narcolepsy, Internal medicine, Endocrinology, Orexin and Cataplexy. His Narcolepsy research incorporates elements of Sleep disorder, Disease and Pediatrics. His work in Internal medicine tackles topics such as Wakefulness which are related to areas like Sleep deprivation, Arousal, Locus coeruleus and Stimulation.
His Endocrinology study combines topics in areas such as Phenotype and Rapid eye movement sleep. His Orexin research is included under the broader classification of Receptor. His Cataplexy research includes themes of Positional cloning, Modafinil and Polysomnography.
His scientific interests lie mostly in Narcolepsy, Internal medicine, Endocrinology, Cataplexy and Orexin. The concepts of his Narcolepsy study are interwoven with issues in Sleep disorder, Excessive daytime sleepiness and Modafinil. His research investigates the connection with Internal medicine and areas like Sleep in non-human animals which intersect with concerns in Insomnia.
His work on Circadian rhythm as part of general Endocrinology study is frequently linked to Chemistry, therefore connecting diverse disciplines of science. His Cataplexy research incorporates themes from Multiple Sleep Latency Test, Anesthesia, Cholinergic, Polysomnography and Pediatrics. The Orexin study combines topics in areas such as Pathophysiology, Disease, Immunology and Neurotransmission.
Seiji Nishino mostly deals with Internal medicine, Endocrinology, Narcolepsy, Orexin and Cataplexy. His Internal medicine research integrates issues from Cell and Cardiology. His Histamine study in the realm of Endocrinology interacts with subjects such as Chemistry.
Seiji Nishino has included themes like Cerebrospinal fluid, Sleep disorder, Excessive daytime sleepiness, Modafinil and Pathophysiology in his Narcolepsy study. His Orexin study integrates concerns from other disciplines, such as Neurology, Disease and Immunology. His Cataplexy research includes themes of Pediatrics and Clomipramine.
Endocrinology, Internal medicine, Narcolepsy, Orexin and Cerebrospinal fluid are his primary areas of study. His work on Histamine, Circadian rhythm and Circadian clock as part of general Endocrinology research is often related to Chemistry and PER3, thus linking different fields of science. When carried out as part of a general Internal medicine research project, his work on Period is frequently linked to work in Period Circadian Proteins, therefore connecting diverse disciplines of study.
The study incorporates disciplines such as Hypothalamus, Excessive daytime sleepiness and Modafinil in addition to Narcolepsy. His biological study spans a wide range of topics, including Cataplexy, Antigen and Gene knockout. Orexin a hypocretin 1, Sleep disorder and HYPOCRETIN 1 is closely connected to Radioimmunoassay in his research, which is encompassed under the umbrella topic of Cerebrospinal fluid.
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The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene
Ling Lin;Juliette Faraco;Robin Li;Hiroshi Kadotani.
Cell (1999)
A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains
Christelle Peyron;Juliette Faraco;William Rogers;Beth Ripley.
Nature Medicine (2000)
Hypocretin (orexin) deficiency in human narcolepsy
Seiji Nishino;Beth Ripley;Sebastiaan Overeem;Gert Jan Lammers.
The Lancet (2000)
Amyloid-β Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle
Jae Eun Kang;Miranda M. Lim;Randall J. Bateman;James J. Lee.
Science (2009)
The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias.
Emmanuel Mignot;Gert Jan Lammers;Beth Ripley;Michele Okun.
JAMA Neurology (2002)
Dopaminergic role in stimulant-induced wakefulness.
Jonathan P. Wisor;Seiji Nishino;Ichiro Sora;George H. Uhl.
The Journal of Neuroscience (2001)
Tuning arousal with optogenetic modulation of locus coeruleus neurons.
Matthew E Carter;Ofer Yizhar;Sachiko Chikahisa;Sachiko Chikahisa;Hieu Nguyen.
Nature Neuroscience (2010)
Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome
Sergiu P Paşca;Thomas Portmann;Irina Voineagu;Masayuki Yazawa.
Nature Medicine (2011)
Low cerebrospinal fluid hypocretin (orexin) and altered energy homeostasis in human narcolepsy
Seiji Nishino;Beth Ripley;Sebastiaan Overeem;Sebastiaan Overeem;Sona Nevsimalova.
Annals of Neurology (2001)
Pharmacological aspects of human and canine narcolepsy
Seiji Nishino;Emmanuel Mignot.
Progress in Neurobiology (1997)
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