D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 73 Citations 26,475 262 World Ranking 15517 National Ranking 7936

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Gene
  • Dopamine

Seiji Nishino mainly focuses on Narcolepsy, Internal medicine, Endocrinology, Orexin and Cataplexy. His Narcolepsy research incorporates elements of Sleep disorder, Disease and Pediatrics. His work in Internal medicine tackles topics such as Wakefulness which are related to areas like Sleep deprivation, Arousal, Locus coeruleus and Stimulation.

His Endocrinology study combines topics in areas such as Phenotype and Rapid eye movement sleep. His Orexin research is included under the broader classification of Receptor. His Cataplexy research includes themes of Positional cloning, Modafinil and Polysomnography.

His most cited work include:

  • The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene (2150 citations)
  • A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains (1674 citations)
  • Hypocretin (orexin) deficiency in human narcolepsy (1413 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Narcolepsy, Internal medicine, Endocrinology, Cataplexy and Orexin. The concepts of his Narcolepsy study are interwoven with issues in Sleep disorder, Excessive daytime sleepiness and Modafinil. His research investigates the connection with Internal medicine and areas like Sleep in non-human animals which intersect with concerns in Insomnia.

His work on Circadian rhythm as part of general Endocrinology study is frequently linked to Chemistry, therefore connecting diverse disciplines of science. His Cataplexy research incorporates themes from Multiple Sleep Latency Test, Anesthesia, Cholinergic, Polysomnography and Pediatrics. The Orexin study combines topics in areas such as Pathophysiology, Disease, Immunology and Neurotransmission.

He most often published in these fields:

  • Narcolepsy (60.94%)
  • Internal medicine (55.86%)
  • Endocrinology (53.12%)

What were the highlights of his more recent work (between 2012-2021)?

  • Internal medicine (55.86%)
  • Endocrinology (53.12%)
  • Narcolepsy (60.94%)

In recent papers he was focusing on the following fields of study:

Seiji Nishino mostly deals with Internal medicine, Endocrinology, Narcolepsy, Orexin and Cataplexy. His Internal medicine research integrates issues from Cell and Cardiology. His Histamine study in the realm of Endocrinology interacts with subjects such as Chemistry.

Seiji Nishino has included themes like Cerebrospinal fluid, Sleep disorder, Excessive daytime sleepiness, Modafinil and Pathophysiology in his Narcolepsy study. His Orexin study integrates concerns from other disciplines, such as Neurology, Disease and Immunology. His Cataplexy research includes themes of Pediatrics and Clomipramine.

Between 2012 and 2021, his most popular works were:

  • Basal forebrain circuit for sleep-wake control (241 citations)
  • A PERIOD3 variant causes a circadian phenotype and is associated with a seasonal mood trait (79 citations)
  • Greatly increased numbers of histamine cells in human narcolepsy with cataplexy. (66 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Gene
  • Dopamine

Endocrinology, Internal medicine, Narcolepsy, Orexin and Cerebrospinal fluid are his primary areas of study. His work on Histamine, Circadian rhythm and Circadian clock as part of general Endocrinology research is often related to Chemistry and PER3, thus linking different fields of science. When carried out as part of a general Internal medicine research project, his work on Period is frequently linked to work in Period Circadian Proteins, therefore connecting diverse disciplines of study.

The study incorporates disciplines such as Hypothalamus, Excessive daytime sleepiness and Modafinil in addition to Narcolepsy. His biological study spans a wide range of topics, including Cataplexy, Antigen and Gene knockout. Orexin a hypocretin 1, Sleep disorder and HYPOCRETIN 1 is closely connected to Radioimmunoassay in his research, which is encompassed under the umbrella topic of Cerebrospinal fluid.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene

Ling Lin;Juliette Faraco;Robin Li;Hiroshi Kadotani.
Cell (1999)

2855 Citations

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

Christelle Peyron;Juliette Faraco;William Rogers;Beth Ripley.
Nature Medicine (2000)

2223 Citations

Hypocretin (orexin) deficiency in human narcolepsy

Seiji Nishino;Beth Ripley;Sebastiaan Overeem;Gert Jan Lammers.
The Lancet (2000)

1925 Citations

Amyloid-β Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle

Jae Eun Kang;Miranda M. Lim;Randall J. Bateman;James J. Lee.
Science (2009)

1327 Citations

The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias.

Emmanuel Mignot;Gert Jan Lammers;Beth Ripley;Michele Okun.
JAMA Neurology (2002)

1210 Citations

Dopaminergic role in stimulant-induced wakefulness.

Jonathan P. Wisor;Seiji Nishino;Ichiro Sora;George H. Uhl.
The Journal of Neuroscience (2001)

826 Citations

Tuning arousal with optogenetic modulation of locus coeruleus neurons.

Matthew E Carter;Ofer Yizhar;Sachiko Chikahisa;Sachiko Chikahisa;Hieu Nguyen.
Nature Neuroscience (2010)

799 Citations

Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome

Sergiu P Paşca;Thomas Portmann;Irina Voineagu;Masayuki Yazawa.
Nature Medicine (2011)

570 Citations

Low cerebrospinal fluid hypocretin (orexin) and altered energy homeostasis in human narcolepsy

Seiji Nishino;Beth Ripley;Sebastiaan Overeem;Sebastiaan Overeem;Sona Nevsimalova.
Annals of Neurology (2001)

522 Citations

Pharmacological aspects of human and canine narcolepsy

Seiji Nishino;Emmanuel Mignot.
Progress in Neurobiology (1997)

492 Citations

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