World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
67
Citations
16080
World Ranking
1572
National Ranking
792

Overview

Lihua Julie Zhu is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a focus on molecular biology, immunology, cancer research, physiology, and oncology.

Their body of work includes significant contributions to topics such as:

  • CRISPR and Genetic Engineering
  • Mitochondrial Function and Pathology
  • Immune cells in cancer
  • Cancer, Hypoxia, and Metabolism
  • Adipose Tissue and Metabolism
  • Genomics and Chromatin Dynamics
  • RNA modifications and cancer

Lihua Julie Zhu's recent publications include:

  • "Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription" (2020, Cell Stem Cell)
  • "Selenium detoxification is required for cancer-cell survival" (2020, Nature Metabolism)
  • "Replication Gaps Underlie BRCA Deficiency and Therapy Response" (2020, Cancer Research)
  • "An improved zebrafish transcriptome annotation for sensitive and comprehensive detection of cell type-specific genes" (2020, eLife)
  • "UPRmt scales mitochondrial network expansion with protein synthesis via mitochondrial import in Caenorhabditis elegans" (2021, Nature Communications)

The frequent co-authors collaborating with Zhu include Rui Li, Haibo Liu, Marcus Ruscetti, Karl Simin, and Kai Hu. They have contributed extensively to fields within molecular biology and cancer research through these collaborations.

Zhu's research has been published predominantly in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Cancer Research, Proceedings of the National Academy of Sciences, and Cell Reports. These publication outlets reflect a broad participation in both preprint and peer-reviewed journals relevant to biomedical sciences.

Best Publications

  • ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data

    Lihua Julie Zhu;Claude Gazin;Nathan D. Lawson;Herve Pages

  • Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases

    Xiangdong Meng;Marcus Blaine Noyes;Lihua Julie Zhu;Nathan D. Lawson

  • Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo

    Hao Yin;Chun-Qing Song;Joseph R. Dorkin;Lihua Julie Zhu

  • Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome

    Christine M. Oslowski;Takashi Hara;Takashi Hara;Takashi Hara;Bryan O'Sullivan-Murphy;Kohsuke Kanekura;Kohsuke Kanekura

  • Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing

    Hao Yin;Chun-Qing Song;Sneha Suresh;Qiongqiong Wu

  • Prominin2 Drives Ferroptosis Resistance by Stimulating Iron Export

    Caitlin W. Brown;John J. Amante;Peter Chhoy;Ameer L. Elaimy

  • Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants.

    Ankita Bansal;Lihua Julie Zhu;Kelvin Yen;Heidi A. Tissenbaum

  • Diet-Induced Developmental Acceleration Independent of TOR and Insulin in C. elegans

    Lesley T. MacNeil;Emma Watson;H. Efsun Arda;Lihua Julie Zhu

  • Annotating the human genome with Disease Ontology

    John D. Osborne;Jared M. Flatow;Michelle Holko;Simon M. Lin

  • FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system

    Lihua Julie Zhu;Ryan G. Christensen;Majid Kazemian;Christopher J. Hull

  • Tead and AP1 Coordinate Transcription and Motility

    Xiangfan Liu;Huapeng Li;Mihir S. Rajurkar;Qi Li

  • Partial DNA-guided Cas9 enables genome editing with reduced off-target activity.

    Hao Yin;Chun-Qing Song;Sneha Suresh;Suet-Yan Kwan

  • CRISPRseek: a bioconductor package to identify target-specific guide RNAs for CRISPR-Cas9 genome-editing systems.

    Lihua Julie Zhu;Benjamin R. Holmes;Neil Aronin;Michael H. Brodsky

  • ATACseqQC: a Bioconductor package for post-alignment quality assessment of ATAC-seq data.

    Jianhong Ou;Haibo Liu;Jun Yu;Michelle A. Kelliher

  • A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications

    Zhi Sheng;Li Li;Lihua Julie Zhu;Thomas W. Smith

  • miR-221 Is Required for Endothelial Tip Cell Behaviors during Vascular Development

    Stefania Nicoli;Carl-Philipp Knyphausen;Carl-Philipp Knyphausen;Lihua Julie Zhu;Abirami Lakshmanan

  • TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein

    Sanchita Bhatnagar;Claude Gazin;Lynn Chamberlain;Jianhong Ou

  • trackViewer: a Bioconductor package for interactive and integrative visualization of multi-omics data

    Jianhong Ou;Lihua Julie Zhu

  • Adenine base editing in an adult mouse model of tyrosinaemia.

    Chun-Qing Song;Tingting Jiang;Michelle Richter;Michelle Richter;Michelle Richter;Luke H. Rhym

  • DNA-binding-domain fusions enhance the targeting range and precision of Cas9

    Mehmet Fatih Bolukbasi;Ankit Gupta;Sarah Oikemus;Alan G Derr

Frequent Co-Authors

Scot A. Wolfe
Scot A. Wolfe University of Massachusetts Chan Medical School
Nathan D. Lawson
Nathan D. Lawson University of Massachusetts Chan Medical School
Paul D. Kaufman
Paul D. Kaufman University of Massachusetts Chan Medical School
Erik J. Sontheimer
Erik J. Sontheimer University of Massachusetts Chan Medical School
Oliver J. Rando
Oliver J. Rando University of Massachusetts Chan Medical School
Arthur M. Mercurio
Arthur M. Mercurio University of Massachusetts Chan Medical School
Fumihiko Urano
Fumihiko Urano Washington University in St. Louis
Y. Tony Ip
Y. Tony Ip University of Massachusetts Chan Medical School
Ximing J. Yang
Ximing J. Yang Northwestern University

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