D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 52 Citations 10,533 149 World Ranking 1695 National Ranking 853

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Gene expression

His primary areas of investigation include Computational biology, Genetics, Cas9, Genome editing and Signal transduction. His research in Computational biology intersects with topics in Annotation, DNA, Nuclease, Bioconductor and In vivo. His work in Gene, Zinc finger nuclease, Zebrafish, Locus and Caenorhabditis elegans are all subfields of Genetics research.

His work carried out in the field of Cas9 brings together such families of science as RNA and Subgenomic mRNA. His Signal transduction study is associated with Cell biology. His work in the fields of Cell biology, such as Unfolded protein response, intersects with other areas such as EIF-2 kinase.

His most cited work include:

  • Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases (684 citations)
  • ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data (574 citations)
  • Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo (504 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Cell biology, Cancer research, Computational biology, Genetics and Transcription factor. His study explores the link between Cell biology and topics such as Chromatin that cross with problems in Epigenetics. His Cancer research research includes themes of Gene knockdown, Signal transduction, Kinase, MAPK/ERK pathway and Transforming growth factor.

Lihua Julie Zhu interconnects Genome editing, Genome, CRISPR, Annotation and Bioconductor in the investigation of issues within Computational biology. His Genome research integrates issues from Enhancer and Zebrafish. His Genetics study is mostly concerned with Gene and Alternative splicing.

He most often published in these fields:

  • Cell biology (36.94%)
  • Cancer research (22.29%)
  • Computational biology (19.75%)

What were the highlights of his more recent work (between 2019-2021)?

  • Cell biology (36.94%)
  • Gene (14.65%)
  • Computational biology (19.75%)

In recent papers he was focusing on the following fields of study:

Lihua Julie Zhu mostly deals with Cell biology, Gene, Computational biology, Transcription factor and Phenotype. In general Cell biology, his work in Erythropoietin receptor is often linked to Erythropoiesis linking many areas of study. Lihua Julie Zhu combines subjects such as Spermatogenic Cell and Embryo with his study of Gene.

His work deals with themes such as Bioconductor and Genome, which intersect with Computational biology. Lihua Julie Zhu has researched Transcription factor in several fields, including Wnt signaling pathway, Signal transduction, MAPK/ERK pathway, Mitochondrial unfolded protein response and Mitochondrion. His Phenotype study is concerned with the larger field of Genetics.

Between 2019 and 2021, his most popular works were:

  • Adenine base editing in an adult mouse model of tyrosinaemia. (62 citations)
  • Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription (20 citations)
  • Selenium detoxification is required for cancer-cell survival. (12 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Cancer

Cell biology, Gene, Enhancer, RNA-Seq and Cancer are his primary areas of study. His studies in Cell biology integrate themes in fields like Chromatin, Embryonic stem cell and Constitutive heterochromatin. When carried out as part of a general Gene research project, his work on Mutation, RNA and Point mutation is frequently linked to work in Fumarylacetoacetate hydrolase and Cisplatin, therefore connecting diverse disciplines of study.

His RNA-Seq research incorporates elements of Annotation, Genome, Ensembl and Zebrafish. His Genome study incorporates themes from Metadata, Computational biology and Accession number. His Cancer study combines topics in areas such as DNA replication, DNA, Homologous recombination, DNA repair and Programmed cell death.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases

Xiangdong Meng;Marcus Blaine Noyes;Lihua Julie Zhu;Nathan D. Lawson.
Nature Biotechnology (2008)

909 Citations

ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data

Lihua Julie Zhu;Claude Gazin;Nathan D. Lawson;Herve Pages.
BMC Bioinformatics (2010)

836 Citations

Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo

Hao Yin;Chun-Qing Song;Joseph R. Dorkin;Lihua Julie Zhu.
Nature Biotechnology (2016)

768 Citations

Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome

Christine M. Oslowski;Takashi Hara;Takashi Hara;Takashi Hara;Bryan O'Sullivan-Murphy;Kohsuke Kanekura;Kohsuke Kanekura.
Cell Metabolism (2012)

603 Citations

Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing

Hao Yin;Chun-Qing Song;Sneha Suresh;Qiongqiong Wu.
Nature Biotechnology (2017)

330 Citations

Annotating the human genome with Disease Ontology

John D. Osborne;Jared M. Flatow;Michelle Holko;Simon M. Lin.
BMC Genomics (2009)

293 Citations

Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants.

Ankita Bansal;Lihua Julie Zhu;Kelvin Yen;Heidi A. Tissenbaum.
Proceedings of the National Academy of Sciences of the United States of America (2015)

278 Citations

Diet-Induced Developmental Acceleration Independent of TOR and Insulin in C. elegans

Lesley T. MacNeil;Emma Watson;H. Efsun Arda;Lihua Julie Zhu.
Cell (2013)

246 Citations

FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system

Lihua Julie Zhu;Ryan G. Christensen;Majid Kazemian;Christopher J. Hull.
Nucleic Acids Research (2011)

231 Citations

CRISPRseek: a bioconductor package to identify target-specific guide RNAs for CRISPR-Cas9 genome-editing systems.

Lihua Julie Zhu;Benjamin R. Holmes;Neil Aronin;Michael H. Brodsky.
PLOS ONE (2014)

184 Citations

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