Toni Cathomen mostly deals with Genetics, Zinc finger, Zinc finger nuclease, Genome editing and Transcription activator-like effector nuclease. His study in Genetics concentrates on Genome, Human genome, Endonuclease and Gene. His Zinc finger nuclease research includes elements of Cleavage, Homologous recombination, Locus, Gene targeting and Computational biology.
His Gene targeting research includes themes of Gene conversion and Cell biology. In his study, which falls under the umbrella issue of Genome editing, Virus and Virology is strongly linked to DNA. His study in Transcription activator-like effector nuclease is interdisciplinary in nature, drawing from both Nuclease and Effector.
The scientist’s investigation covers issues in Genetics, Genome editing, Gene, Transcription activator-like effector nuclease and Zinc finger nuclease. His study in Genome, Genetic enhancement, Human genome, Gene targeting and Induced pluripotent stem cell are all subfields of Genetics. He interconnects Gene rearrangement, DNA sequencing and Endonuclease in the investigation of issues within Genome.
His Genome editing research integrates issues from Computational biology and DNA, Nuclease. His Transcription activator-like effector nuclease research is multidisciplinary, incorporating elements of Effector, Haematopoiesis, Stem cell, Cell biology and Virology. Zinc finger nuclease is a subfield of Zinc finger that Toni Cathomen studies.
Toni Cathomen spends much of his time researching Genome editing, Gene, Transcription activator-like effector nuclease, CRISPR and Cell biology. His studies in Genome editing integrate themes in fields like Human genome and Transplantation. His research integrates issues of Jurkat cells and Computational biology in his study of Gene.
His Transcription activator-like effector nuclease research incorporates elements of Stem cell, Electroporation and Effector. CRISPR is a subfield of Genetics that Toni Cathomen explores. Toni Cathomen studies Genetics, focusing on Mutation in particular.
His scientific interests lie mostly in Genome editing, Transcription activator-like effector nuclease, CRISPR, Haematopoiesis and Hematopoietic stem cell. His Genome editing study frequently draws connections between adjacent fields such as Stem cell. His Stem cell study combines topics in areas such as Gene, Nuclease, Homologous recombination, Chromosomal translocation and Computational biology.
His Transcription activator-like effector nuclease study frequently draws connections to adjacent fields such as Effector. His research in Effector intersects with topics in Genetics, Transcription, In silico and Genetic enhancement. His research ties Human genome and CRISPR together.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity
Claudio Mussolino;Robert Morbitzer;Fabienne Lütge;Nadine Dannemann.
Nucleic Acids Research (2011)
Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification.
Morgan L. Maeder;Stacey Thibodeau-Beganny;Anna Osiak;David A. Wright.
Molecular Cell (2008)
Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations.
Desireé Schubert;Desireé Schubert;Claudia Bode;Rupert Kenefeck;Tie Zheng Hou.
Nature Medicine (2014)
Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases.
Michal Szczepek;Vincent Brondani;Janine Büchel;Luis Serrano.
Nature Biotechnology (2007)
Unexpected failure rates for modular assembly of engineered zinc fingers
Cherie L Ramirez;Jonathan E Foley;David A Wright;Felix Müller-Lerch.
Nature Methods (2008)
Zinc-finger Nucleases: The Next Generation Emerges
Toni Cathomen;J Keith Joung.
Molecular Therapy (2008)
Measles Viruses with Altered Envelope Protein Cytoplasmic Tails Gain Cell Fusion Competence
Toni Cathomen;Hussein Y. Naim;Roberto Cattaneo.
Journal of Virology (1998)
Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells
Maarten Holkers;Ignazio Maggio;Jin Liu;Josephine M. Janssen.
Nucleic Acids Research (2013)
A matrix-less measles virus is infectious and elicits extensive cell fusion: consequences for propagation in the brain
Toni Cathomen;Branka Mrkic;Danièle Spehner;Robert Drillien.
The EMBO Journal (1998)
TALE nucleases: tailored genome engineering made easy.
Claudio Mussolino;Toni Cathomen.
Current Opinion in Biotechnology (2012)
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