What is he best known for?
The fields of study he is best known for:
Toni Cathomen mostly deals with Genetics, Zinc finger, Zinc finger nuclease, Genome editing and Transcription activator-like effector nuclease.
His study in Genetics concentrates on Genome, Human genome, Endonuclease and Gene.
His Zinc finger nuclease research includes elements of Cleavage, Homologous recombination, Locus, Gene targeting and Computational biology.
His Gene targeting research includes themes of Gene conversion and Cell biology.
In his study, which falls under the umbrella issue of Genome editing, Virus and Virology is strongly linked to DNA.
His study in Transcription activator-like effector nuclease is interdisciplinary in nature, drawing from both Nuclease and Effector.
His most cited work include:
- A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity (684 citations)
- Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification. (639 citations)
- Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases. (476 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Genetics, Genome editing, Gene, Transcription activator-like effector nuclease and Zinc finger nuclease.
His study in Genome, Genetic enhancement, Human genome, Gene targeting and Induced pluripotent stem cell are all subfields of Genetics.
He interconnects Gene rearrangement, DNA sequencing and Endonuclease in the investigation of issues within Genome.
His Genome editing research integrates issues from Computational biology and DNA, Nuclease.
His Transcription activator-like effector nuclease research is multidisciplinary, incorporating elements of Effector, Haematopoiesis, Stem cell, Cell biology and Virology.
Zinc finger nuclease is a subfield of Zinc finger that Toni Cathomen studies.
He most often published in these fields:
- Genetics (49.69%)
- Genome editing (42.86%)
- Gene (28.57%)
What were the highlights of his more recent work (between 2018-2021)?
- Genome editing (42.86%)
- Gene (28.57%)
- Transcription activator-like effector nuclease (29.81%)
In recent papers he was focusing on the following fields of study:
Toni Cathomen spends much of his time researching Genome editing, Gene, Transcription activator-like effector nuclease, CRISPR and Cell biology.
His studies in Genome editing integrate themes in fields like Human genome and Transplantation.
His research integrates issues of Jurkat cells and Computational biology in his study of Gene.
His Transcription activator-like effector nuclease research incorporates elements of Stem cell, Electroporation and Effector.
CRISPR is a subfield of Genetics that Toni Cathomen explores.
Toni Cathomen studies Genetics, focusing on Mutation in particular.
Between 2018 and 2021, his most popular works were:
- Biodegradable Nanocarriers Resembling Extracellular Vesicles Deliver Genetic Material with the Highest Efficiency to Various Cell Types. (12 citations)
- Correction of IVS I-110(G>A) β-thalassemia by CRISPR/Cas-and TALEN-mediated disruption of aberrant regulatory elements in human hematopoietic stem and progenitor cells. (12 citations)
- Retroviral UNC13D Gene Transfer Restores Cytotoxic Activity of T Cells Derived from Familial Hemophagocytic Lymphohistiocytosis Type 3 Patients In Vitro. (10 citations)
In his most recent research, the most cited papers focused on:
His scientific interests lie mostly in Genome editing, Transcription activator-like effector nuclease, CRISPR, Haematopoiesis and Hematopoietic stem cell.
His Genome editing study frequently draws connections between adjacent fields such as Stem cell.
His Stem cell study combines topics in areas such as Gene, Nuclease, Homologous recombination, Chromosomal translocation and Computational biology.
His Transcription activator-like effector nuclease study frequently draws connections to adjacent fields such as Effector.
His research in Effector intersects with topics in Genetics, Transcription, In silico and Genetic enhancement.
His research ties Human genome and CRISPR together.
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