Immunology, Molecular biology, Severe combined immunodeficiency, DNA repair and Cell biology are his primary areas of study. His study in Immunology is interdisciplinary in nature, drawing from both Mutation, Hemophagocytic lymphohistiocytosis, Hematopoietic stem cell transplantation and Anemia. His Molecular biology research incorporates elements of LIG4 syndrome, DNA-PKcs, Ku80, Endonuclease and LIG4.
His Severe combined immunodeficiency research is multidisciplinary, incorporating perspectives in DCLRE1C, Recombination-activating gene, Omenn syndrome, CD8 and Graft-versus-host disease. His studies in DCLRE1C integrate themes in fields like Non-homologous end joining and Gene rearrangement. His Cell biology study integrates concerns from other disciplines, such as Immune system, Chemotaxis and DNA, DNA polymerase.
Klaus Schwarz mainly focuses on Immunology, Molecular biology, Immunodeficiency, Genetics and Severe combined immunodeficiency. His Immunology research integrates issues from Mutation, Hematopoietic stem cell transplantation, Transplantation and Autoimmune lymphoproliferative syndrome. His Molecular biology study incorporates themes from DNA repair protein XRCC4, Non-homologous end joining, VJ recombination, DNA and Antigen.
As part of the same scientific family, Klaus Schwarz usually focuses on Immunodeficiency, concentrating on Pathology and intersecting with Antibody. The concepts of his Severe combined immunodeficiency study are interwoven with issues in Gene rearrangement, Virology, T cell, Omenn syndrome and Disease. His Omenn syndrome study combines topics in areas such as DCLRE1C and RAG2.
Klaus Schwarz mainly investigates Immunology, Immune system, Cell biology, Hematopoietic stem cell transplantation and Immunodeficiency. His work deals with themes such as Treatment outcome and Graft survival, which intersect with Immunology. His study on Immune system also encompasses disciplines like
His studies examine the connections between Cell biology and genetics, as well as such issues in Receptor-mediated endocytosis, with regards to Function, Antigen and Clathrin. His study focuses on the intersection of Hematopoietic stem cell transplantation and fields such as Severe combined immunodeficiency with connections in the field of Somatic cell, Progenitor cell, Reversion and Robustness. His biological study spans a wide range of topics, including Missense mutation, Sepsis and Splice site mutation.
Klaus Schwarz focuses on Immunology, Inflammation, Immunodeficiency, Immune system and Antibody. Klaus Schwarz regularly links together related areas like Mutation in his Immunology studies. His Immunodeficiency research includes elements of Inflammasome, Primary immunodeficiency, Programmed cell death and Pathogenesis.
The Immune system study combines topics in areas such as HLA-DR and Enteropathy. His work in Antibody tackles topics such as Subcutaneous Panniculitis-Like T-Cell Lymphoma which are related to areas like Hematopoietic stem cell transplantation. His Hematopoietic stem cell transplantation research incorporates elements of Lymphoma, Prevalence, Age of onset, Adipose tissue and Pediatrics.
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Hairpin Opening and Overhang Processing by an Artemis/DNA-Dependent Protein Kinase Complex in Nonhomologous End Joining and V(D)J Recombination
Yunmei Ma;Ulrich Pannicke;Klaus Schwarz;Michael R. Lieber.
Mechanism and regulation of human non-homologous DNA end-joining
Michael R. Lieber;Yunmei Ma;Ulrich Pannicke;Klaus Schwarz.
Nature Reviews Molecular Cell Biology (2003)
RAG Mutations in Human B Cell-Negative SCID
Klaus Schwarz;George H. Gauss;Leopold Ludwig;Ulrich Pannicke.
Regulated Expression of Nuclear Receptor RORγt Confers Distinct Functional Fates to NK Cell Receptor-Expressing RORγt+ Innate Lymphocytes
Cedric Vonarbourg;Arthur Mortha;Viet L. Bui;Viet L. Bui;Pedro P. Hernandez;Pedro P. Hernandez.
Partial V(D)J Recombination Activity Leads to Omenn Syndrome
Anna Villa;Sandro Santagata;Fabio Bozzi;Silvia Giliani.
DNA Ligase IV Is Essential for V(D)J Recombination and DNA Double-Strand Break Repair in Human Precursor Lymphocytes
Ulf Grawunder;David Zimmer;Sebastian Fugmann;Klaus Schwarz.
Molecular Cell (1998)
A Biochemically Defined System for Mammalian Nonhomologous DNA End Joining
Yunmei Ma;Haihui Lu;Brigette Tippin;Myron F. Goodman.
Molecular Cell (2004)
A bound form of silicon in glycosaminoglycans and polyuronides.
Proceedings of the National Academy of Sciences of the United States of America (1973)
V(D)J recombination defects in lymphocytes due to RAG mutations: severe immunodeficiency with a spectrum of clinical presentations.
Anna Villa;Cristina Sobacchi;Luigi D. Notarangelo;Fabio Bozzi.
Autoimmunity in Wiskott-Aldrich syndrome: risk factors, clinical features, and outcome in a single-center cohort of 55 patients.
Sophie Dupuis-Girod;Jacques Medioni;Elie Haddad;Pierre Quartier.
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