World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
18494
World Ranking
6303
National Ranking
484

Research.com Recognitions

  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Frances M. Brodsky is affiliated with University College London in the United Kingdom. Their research primarily focuses on Biochemistry, Genetics and Molecular Biology, with notable contributions in Molecular Biology, Cell Biology, Immunology, Genetics, and Surgery.

The scientist's work encompasses several main topics, including:

  • Cellular transport and secretion
  • Microtubule and mitosis dynamics
  • Retinal Development and Disorders
  • Lipid Membrane Structure and Behavior
  • Metabolism, Diabetes, and Cancer
  • Ubiquitin and proteasome pathways
  • Signaling Pathways in Disease

Frances M. Brodsky has contributed to multiple research papers, with recent publications including:

  • Building GLUT4 Vesicles: CHC22 Clathrin's Human Touch, 2020, Trends in Cell Biology
  • Clathrin light chain diversity regulates membrane deformation in vitro and synaptic vesicle formation in vivo, 2020, Proceedings of the National Academy of Sciences
  • Clathrin's life beyond 40: Connecting biochemistry with physiology and disease, 2020, Current Opinion in Cell Biology
  • Trafficking regulator of GLUT4-1 (TRARG1) is a GSK3 substrate, 2022, Biochemical Journal
  • Antagonistic regulation controls clathrin-mediated endocytosis: AP2 adaptor facilitation vs restraint from clathrin light chains, 2021, Cells and Development

The scientist frequently publishes in journals such as:

  • FEBS Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Current Opinion in Cell Biology
  • Traffic

Among frequent collaborators are:

  • Séamus J. Martin
  • Dublin Chair
  • Andrey Abramov
  • Colin Adrain
  • Cecília M. Arraiano

Frances M. Brodsky holds recognitions including membership in the European Molecular Biology Organization (EMBO) and fellowship in The Academy of Medical Sciences, United Kingdom.

Best Publications

  • Biological basket weaving: formation and function of clathrin-coated vesicles.

    Frances M. Brodsky;Chih-Ying Chen;Christine Knuehl;Mhairi C. Towler

  • Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission

    Stefanie Sowinski;Clare Jolly;Otto Berninghausen;Marco A. Purbhoo

  • Monoclonal antibodies for analysis of the HLA system.

    Frances M. Brodsky;Peter Parham;Colin J. Barnstable;M. J. Crumpton

  • Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds

    Brandon B. Holmes;Sarah L. DeVos;Najla Kfoury;Mei Li

  • Co-localization of molecules involved in antigen processing and presentation in an early endocytic compartment.

    Lynne E. Guagliardi;Bruce Koppelman;Janice S. Blum;Michael S. Marks

  • The Cell Biology of Antigen Processing and Presentation

    Frances M. Brodsky;Lynne E. Guagliardi

  • Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells.

    Dun Yang;Frank Buchholz;Zhongdong Huang;Andrei Goga

  • Partial purification and some properties of BB7.2. A cytotoxic monoclonal antibody with specificity for HLA-A2 and a variant of HLA-A28.

    Peter Parham;Frances M. Brodsky

  • Monoclonal antibodies: Purification, fragmentation and application to structural and functional studies of class I MHC antigens

    Peter Parham;Matthew J. Androlewicz;Frances M. Brodsky;Nicholas J. Holmes

  • EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake.

    Andrew Wilde;Eric C Beattie;Lawrence Lem;David A Riethof

  • Characterization of a monoclonal anti-beta 2-microglobulin antibody and its use in the genetic and biochemical analysis of major histocompatibility antigens.

    Frances M. Brodsky;Walter F. Bodmer;Peter Parham

  • Living with clathrin: its role in intracellular membrane traffic.

    Frances M. Brodsky

  • Monomorphic anti-HLA-A,B,C monoclonal antibodies detecting molecular subunits and combinatorial determinants.

    F M Brodsky;P Parham

  • Interactions between HIV1 Nef and Vacuolar ATPase Facilitate the Internalization of CD4

    Xiaobin Lu;Haifeng Yu;Shu-Hui Liu;Frances M Brodsky

  • A monoclonal antibody that recognizes an antigenic determinant shared by HLA A2 and B17

    Andrew J. McMichael;Andrew J. McMichael;Peter Parham;Peter Parham;Nigel Rust;Nigel Rust;Frances Brodsky;Frances Brodsky

  • TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis

    Thomas T. Chen;Li Li;Dong-Hui Chung;Christopher D.C. Allen

  • Cutting edge: adenovirus E19 has two mechanisms for affecting class I MHC expression.

    Elizabeth M. Bennett;Jack R. Bennink;Jonathan W. Yewdell;Frances M. Brodsky

  • Lipid Rafts Unite Signaling Cascades with Clathrin to Regulate BCR Internalization

    Angela Stoddart;Michelle L Dykstra;Bruce K Brown;Wenxia Song

  • Diversity of clathrin function: new tricks for an old protein.

    Frances M Brodsky

  • A cost-benefit analysis of the physical mechanisms of membrane curvature

    Jeanne Casstevens Stachowiak;Frances M. Brodsky;Elizabeth A. Miller

Frequent Co-Authors

Peter Parham
Peter Parham Stanford University
Mark Marsh
Mark Marsh University College London
Robert J. Fletterick
Robert J. Fletterick University of California, San Francisco
Pascale Cossart
Pascale Cossart Institut Pasteur
Michael S. Marks
Michael S. Marks Children's Hospital of Philadelphia
Robert G. Parton
Robert G. Parton University of Queensland
Mark G. Thomas
Mark G. Thomas University College London
Sandra L. Schmid
Sandra L. Schmid The University of Texas Southwestern Medical Center
Franck Perez
Franck Perez PSL University
Gwyn W. Gould
Gwyn W. Gould University of Strathclyde

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