Robert J. Fletterick

Research.com Recognitions

• 2010 - Member of the National Academy of Sciences

Overview

Best Publications

• Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins.

  K M Pan;M Baldwin;J Nguyen;M Gasset

  3119
  Citations

• Structure and specificity of nuclear receptor-coactivator interactions.

  Beatrice D. Darimont;Richard L. Wagner;James W. Apriletti;Michael R. Stallcup

  1172
  Citations

• A structural role for hormone in the thyroid hormone receptor

  Richard L. Wagner;James W. Apriletti;Mary E. McGrath;Brian L. West

  1153
  Citations

• Crystal structure of the kinesin motor domain reveals a structural similarity to myosin.

  F.J Kull;E.P Sablin;R Lau;R.J Fletterick

  871
  Citations

• Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors

  Weijun Feng;Ralff C. J. Ribeiro;Ralff C. J. Ribeiro;Richard L. Wagner;Richard L. Wagner;Hoa Nguyen;Hoa Nguyen

  740
  Citations

• Structural clues to prion replication

  Fred E. Cohen;Keh-Ming Pan;Ziwei Huang;Michael Baldwin

  705
  Citations

• The design plan of kinesin motors

  Ronald D. Vale;Robert J. Fletterick

  645
  Citations

• The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity.

  Sarah A. Gillmor;Armando Villaseñor;Robert Fletterick;Elliott Sigal

  597
  Citations

• Viral cysteine proteases are homologous to the trypsin-like family of serine proteases: structural and functional implications.

  J F Bazan;R J Fletterick

  554
  Citations

• Redesigning trypsin: alteration of substrate specificity

  Charles S. Craik;Corey Largman;Thomas Fletcher;Steven Roczniak

  502
  Citations

• Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1.

  Irina N. Krylova;Elena P. Sablin;Jamie Moore;Robert X. Xu

  492
  Citations

• Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein.

  T J Chambers;R C Weir;A Grakoui;D W McCourt

  484
  Citations

• The family of glycogen phosphorylases: structure and function.

  Christopher B. Newgard;Peter K. Hwang;Robert J. Fletterick

  479
  Citations

• Nuclear receptor ligands and ligand binding domains

  Thomas S. Scanlan;John D. Baxter;Robert J. Fletterick;Richard L. Wagner

  474
  Citations

• Crystal structure of the motor domain of the kinesin-related motor ncd

  Sablin Ep;Kull Fj;Cooke R;Vale Rd

  449
  Citations

• Predicted alpha-helical regions of the prion protein when synthesized as peptides form amyloid.

  Maria Gasset;Michael A. Baldwin;David H. Lloyd;Jean-Marc Gabriel

  447
  Citations

• Switch-based Mechanism of Kinesin Motors

  Masahide Kikkawa;Elena P. Sablin;Yasushi Okada;Hiroaki Yajima

  430
  Citations

• Structural changes in glycogen phosphorylase induced by phosphorylation.

  S. R. Sprang;K. R. Acharya;Elizabeth J Goldsmith;D. I. Stuart

  366
  Citations

• Perturbation of the secondary structure of the scrapie prion protein under conditions that alter infectivity

  Maria Gasset;Michael A. Baldwin;Robert J. Fletterick;Stanley B. Prusiner

  363
  Citations

• A surface on the androgen receptor that allosterically regulates coactivator binding.

  Eva Estébanez-Perpiñá;Leggy A. Arnold;Phuong Nguyen;Edson Delgado Rodrigues

  361
  Citations

• Ca2+-regulated structural changes in troponin

  Maia V. Vinogradova;Deborah B. Stone;Galina G. Malanina;Christina Karatzaferi

  350
  Citations