What is he best known for?
The fields of study he is best known for:
His primary areas of study are Biochemistry, Stereochemistry, Protein structure, Binding site and Adenylyl cyclase.
In the field of Biochemistry, his study on G protein, G alpha subunit and Heat shock protein overlaps with subjects such as Structural unit.
His research in G protein is mostly concerned with GTPase-activating protein.
His research in Stereochemistry intersects with topics in Heterotrimeric G protein and Active site.
His Protein structure study incorporates themes from Crystallography, Receptor and Extracellular.
The Binding site study combines topics in areas such as Antiparallel, Recombinant DNA, Dimer, Trimer and Trypsin.
His most cited work include:
- The structure of the G protein heterotrimer Giα1β1γ2 (991 citations)
- G PROTEIN MECHANISMS: Insights from Structural Analysis (920 citations)
- Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis. (739 citations)
What are the main themes of his work throughout his whole career to date?
Stephen R. Sprang mainly investigates Biochemistry, G protein, Stereochemistry, Heterotrimeric G protein and Cell biology.
His study in Biochemistry focuses on Adenylyl cyclase, G beta-gamma complex, Glycogen phosphorylase, Enzyme and Gs alpha subunit.
Stephen R. Sprang interconnects Guanine nucleotide exchange factor, GTPase, G protein-coupled receptor, Biophysics and GTP' in the investigation of issues within G protein.
In his study, which falls under the umbrella issue of Biophysics, Extracellular is strongly linked to Receptor.
His Stereochemistry study integrates concerns from other disciplines, such as Crystallography, Nucleotide, Active site, Protein structure and Binding site.
His Heterotrimeric G protein research integrates issues from Chaperone and G alpha subunit.
He most often published in these fields:
- Biochemistry (45.40%)
- G protein (33.13%)
- Stereochemistry (31.90%)
What were the highlights of his more recent work (between 2010-2020)?
- G protein (33.13%)
- Biochemistry (45.40%)
- Heterotrimeric G protein (24.54%)
In recent papers he was focusing on the following fields of study:
His main research concerns G protein, Biochemistry, Heterotrimeric G protein, Biophysics and Guanine nucleotide exchange factor.
His G protein research includes elements of Cell signaling, G protein-coupled receptor and Chaperone.
His multidisciplinary approach integrates Biochemistry and Nucleotide exchange factor in his work.
His research integrates issues of Gs alpha subunit, GTPase-activating protein and Gq alpha subunit in his study of Heterotrimeric G protein.
Stephen R. Sprang combines subjects such as Nucleotide and Stereochemistry with his study of Guanine nucleotide exchange factor.
Stephen R. Sprang has researched Stereochemistry in several fields, including Peroxidase, Adenylyl cyclase, Protein structure and Heme.
Between 2010 and 2020, his most popular works were:
- Inhibitors of membranous adenylyl cyclases. (81 citations)
- Structure of a mitochondrial cytochrome c conformer competent for peroxidase activity. (67 citations)
- Molecular chaperoning function of Ric-8 is to fold nascent heterotrimeric G protein α subunits (56 citations)
In his most recent research, the most cited papers focused on:
Stephen R. Sprang spends much of his time researching Biochemistry, Stereochemistry, G protein, GTP-Binding Protein alpha Subunits and Heterotrimeric G protein.
His work on Allosteric regulation, Binding site and Signal peptide as part of general Biochemistry research is frequently linked to Junin virus and Glycoprotein complex, bridging the gap between disciplines.
His biological study spans a wide range of topics, including Peroxidase, Electron transport chain, Guanine and Heme.
His G protein research incorporates elements of Guanine nucleotide exchange factor and G protein-coupled receptor.
His GTP-Binding Protein alpha Subunits study combines topics from a wide range of disciplines, such as GTPase-activating protein, Biophysics, Protein subunit, Chaperone and Gs alpha subunit.
GTP-Binding Protein beta Subunits, GTP-Binding Protein gamma Subunits, GTPase and GTP-binding protein regulators is closely connected to GTP' in his research, which is encompassed under the umbrella topic of Heterotrimeric G protein.
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