What is he best known for?
The fields of study he is best known for:
- Enzyme
- Signal transduction
- Amino acid
The scientist’s investigation covers issues in G protein, Biochemistry, Signal transduction, Phospholipase C and Cell biology.
His G protein research is multidisciplinary, incorporating elements of Molecular biology, Adenylyl cyclase and Protein–protein interaction.
His Biochemistry research includes themes of Alpha, Beta and G alpha subunit.
His biological study spans a wide range of topics, including NADPH oxidase, Chemotaxis and Effector.
His Phospholipase C research is multidisciplinary, incorporating perspectives in Protein kinase C, Protein kinase A and Gq alpha subunit.
His work deals with themes such as Receptor and Lipid signaling, which intersect with Cell biology.
His most cited work include:
- Roles of PLC-β2 and -β3 and PI3Kγ in Chemoattractant-Mediated Signal Transduction (769 citations)
- Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq (768 citations)
- A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein βγ subunits (537 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Cell biology, G protein, Biochemistry, Phospholipase C and Signal transduction.
Alan V. Smrcka works mostly in the field of Cell biology, limiting it down to topics relating to Receptor and, in certain cases, Pharmacology and Effector.
The various areas that Alan V. Smrcka examines in his G protein study include Molecular biology and Binding site.
His Biochemistry research integrates issues from Alpha, Beta and G alpha subunit.
His Phospholipase C research incorporates elements of Phospholipase, Endocrinology, Diacylglycerol kinase and Gq alpha subunit.
His research in Signal transduction intersects with topics in Chemotaxis and Phosphorylation.
He most often published in these fields:
- Cell biology (47.75%)
- G protein (46.07%)
- Biochemistry (32.58%)
What were the highlights of his more recent work (between 2017-2021)?
- Cell biology (47.75%)
- G protein-coupled receptor (23.60%)
- Golgi apparatus (6.74%)
In recent papers he was focusing on the following fields of study:
Alan V. Smrcka mainly investigates Cell biology, G protein-coupled receptor, Golgi apparatus, G protein and Receptor.
His Cell biology research incorporates themes from Hydrolysis and Adrenergic receptor.
The G protein-coupled receptor study combines topics in areas such as Endocytic cycle, Cell, Integrin and Motility.
His G protein study necessitates a more in-depth grasp of Signal transduction.
His research integrates issues of Cell signaling and Intracellular in his study of Receptor.
His Phospholipase C study combines topics in areas such as Phosphatidylinositol 4-phosphate, Endocrinology, Diacylglycerol kinase and Protein kinase A.
Between 2017 and 2021, his most popular works were:
- Targeting G protein-coupled receptor signalling by blocking G proteins. (49 citations)
- Golgi localized β1-adrenergic receptors stimulate Golgi PI4P hydrolysis by PLCε to regulate cardiac hypertrophy. (24 citations)
- G-protein βγ subunits as multi-functional scaffolds and transducers in G-protein-coupled receptor signaling. (23 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Signal transduction
- Amino acid
His scientific interests lie mostly in Cell biology, G protein-coupled receptor, Golgi apparatus, G protein and Receptor.
His research in Phospholipase C and Phosphatidylinositol are components of Cell biology.
His study in G protein-coupled receptor is interdisciplinary in nature, drawing from both Stimulation, Computational biology, Signalling and Effector.
His biological study deals with issues like Second messenger system, which deal with fields such as G protein-coupled receptor kinase and G Protein-Coupled Receptor Signaling.
His G protein study is related to the wider topic of Signal transduction.
His Receptor study incorporates themes from Cell and Motility.
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