World's Best Scientists 2026 revealed!

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Neuroscience

D-Index
51
Citations
11205
World Ranking
5477
National Ranking
81

Overview

Youming Lu is affiliated with Huazhong University of Science and Technology in China. Their research primarily focuses on the intersection of biochemistry, genetics, molecular biology, neuroscience, and medicine, with a substantial output in areas relating to molecular biology and cellular and molecular neuroscience.

The scientist's work covers key topics including:

  • Neuroscience and Neuropharmacology Research
  • RNA Research and Splicing
  • MicroRNA in disease regulation
  • Memory and Neural Mechanisms
  • Neuroinflammation and Neurodegeneration Mechanisms
  • RNA regulation and disease
  • Alzheimer's disease research and treatments

Frequent co-authors contributing to their research projects include Ling-Qiang Zhu, Dan Liu, Tongmei Zhang, Heng-Ye Man, and Xian Huang.

Lu has published extensively in several scientific journals, with repeated contributions to:

  • Nature Communications
  • Cell Research
  • Cell Death and Differentiation
  • Aging Cell
  • Neurotherapeutics

Notable recent papers by Youming Lu include:

  • "Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer's disease" (2021, Cell Death and Differentiation)
  • "Targeting miR-124/Ferroportin signaling ameliorated neuronal cell death through inhibiting apoptosis and ferroptosis in aged intracerebral hemorrhage murine model" (2020, Aging Cell)
  • "The emerging role of exosomes in Alzheimer's disease" (2021, Ageing Research Reviews)
  • "miR-135a-5p mediates memory and synaptic impairments via the Rock2/Adducin1 signaling pathway in a mouse model of Alzheimer's disease" (2021, Nature Communications)
  • "PINK1-mediated Drp1S616 phosphorylation modulates synaptic development and plasticity via promoting mitochondrial fission" (2022, Signal Transduction and Targeted Therapy)

Best Publications

  • Mice Lacking Metabotropic Glutamate Receptor 5 Show Impaired Learning and Reduced CA1 Long-Term Potentiation (LTP) But Normal CA3 LTP

    You-Ming Lu;Zhengping Jia;Christopher Janus;Jeffrey T. Henderson

  • Tau-mediated iron export prevents ferroptotic damage after ischemic stroke

    Tuo Qz;Tuo Qz;Tuo Qz;Lei P;Lei P;Jackman Ka;Li Xl

  • Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer's disease.

    Wen Dai Bao;Pei Pang;Xiao Ting Zhou;Fan Hu

  • DAPK1 Interaction with NMDA Receptor NR2B Subunits Mediates Brain Damage in Stroke

    Weihong Tu;Xin Xu;Lisheng Peng;Xiaofen Zhong

  • Src Activation in the Induction of Long-Term Potentiation in CA1 Hippocampal Neurons

    You Ming Lu;John C. Roder;Jonathan Davidow;Michael W. Salter

  • Deregulation of HDAC1 by p25/Cdk5 in Neurotoxicity

    Dohoon Kim;Christopher L. Frank;Christopher L. Frank;Matthew M. Dobbin;Rachel K. Tsunemoto

  • Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors.

    Jian Wang;Shu Hong Liu;Yang Ping Fu;Jerry H. Wang

  • Calcineurin-Mediated LTD of GABAergic Inhibition Underlies the Increased Excitability of CA1 Neurons Associated with LTP

    You Ming Lu;Isabelle M Mansuy;Eric R Kandel;John Roder

  • ADAR2-Dependent RNA Editing of AMPA Receptor Subunit GluR2 Determines Vulnerability of Neurons in Forebrain Ischemia

    Peter L. Peng;Xiafen Zhong;Weihong Tu;Mangala M. Soundarapandian

  • Expression of inducible nitric oxide synthase after focal cerebral ischemia stimulates neurogenesis in the adult rodent dentate gyrus.

    Dong Ya Zhu;Shu Hong Liu;Hong Suo Sun;You Ming Lu

  • Expression of Ca2+-Permeable AMPA Receptor Channels Primes Cell Death in Transient Forebrain Ischemia

    ShuHong Liu;Lorraine Lau;JianShe Wei;DongYa Zhu

  • Selective abolition of the NMDA component of long-term potentiation in mice lacking mGluR5

    Zhengping Jia;YouMing Lu;Jeff Henderson;Franco Taverna

  • Activation of cAMP-response-element-binding protein (CREB) after focal cerebral ischemia stimulates neurogenesis in the adult dentate gyrus.

    Dong Ya Zhu;Lorraine Lau;Shu Hong Liu;Jian She Wei

  • EPAC null mutation impairs learning and social interactions via aberrant regulation of miR-124 and Zif268 translation

    Ying Yang;Xiaogang Shu;Xiaogang Shu;Dan Liu;You Shang;You Shang

  • A Novel MicroRNA-124/PTPN1 Signal Pathway Mediates Synaptic and Memory Deficits in Alzheimer's Disease.

    Xiong Wang;Dan Liu;He-Zhou Huang;Zhi-Hao Wang

  • Generation of Functional Inhibitory Neurons in the Adult Rat Hippocampus

    ShuHong Liu;Jian Wang;DongYa Zhu;YangPing Fu

  • Interaction of Calcineurin and Type-A GABA Receptor γ2 Subunits Produces Long-Term Depression at CA1 Inhibitory Synapses

    Jian Wang;ShuHong Liu;Ursula Haditsch;WeiHong Tu

  • Synaptic released zinc promotes tau hyperphosphorylation by inhibition of protein phosphatase 2A (PP2A).

    Xu-Ying Sun;Yu-Ping Wei;Yan Xiong;Xiao-Chuan Wang;Xiao-Chuan Wang

  • Targeting miR-124/Ferroportin signaling ameliorated neuronal cell death through inhibiting apoptosis and ferroptosis in aged intracerebral hemorrhage murine model.

    Wen-Dai Bao;Xiao-Ting Zhou;Lan-Ting Zhou;Fudi Wang

  • A novel mechanism of memory loss in Alzheimer’s disease mice via the degeneration of entorhinal–CA1 synapses

    Yang X;Yao C;Tian T;Li X

  • Endogenous Zn(2+) is required for the induction of long-term potentiation at rat hippocampal mossy fiber-CA3 synapses.

    You-Ming Lu;Franco A. Taverna;Rita Tu;Cameron A. Ackerley

  • Zinc induces protein phosphatase 2A inactivation and tau hyperphosphorylation through Src dependent PP2A (tyrosine 307) phosphorylation

    Yan Xiong;Xiao-Peng Jing;Xin-Wen Zhou;Xin-Wen Zhou;Xiu-Lian Wang

Frequent Co-Authors

Yu Tian Wang
Yu Tian Wang University of British Columbia
Ronald S. Petralia
Ronald S. Petralia National Institutes of Health
Michael W. Salter
Michael W. Salter University of Toronto
Isabelle M. Mansuy
Isabelle M. Mansuy University of Zurich
J. Martin Wojtowicz
J. Martin Wojtowicz University of Toronto
Nicolas G. Bazan
Nicolas G. Bazan Louisiana State University
Qing-song Liu
Qing-song Liu Medical College of Wisconsin
Frédéric Calon
Frédéric Calon Université Laval
Rachael L. Neve
Rachael L. Neve Harvard University

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