Ashley I. Bush

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in Australia Leader Award
• 2025 - Research.com Biology and Biochemistry in Australia Leader Award
• 2023 - Research.com Biology and Biochemistry in Australia Leader Award
• 2023 - Research.com Medicine in Australia Leader Award

Overview

Best Publications

• Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

  Brent R. Stockwell;José Pedro Friedmann Angeli;Hülya Bayir;Ashley I. Bush

  7001
  Citations

• Neurodegenerative diseases and oxidative stress.

  Kevin J. Barnham;Colin L. Masters;Ashley I. Bush;Ashley I. Bush

  4079
  Citations

• Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease.

  Catriona A. McLean;Robert A. Cherny;Fiona W. Fraser;Stephanie J. Fuller

  2457
  Citations

• The neurobiology of zinc in health and disease

  Christopher J. Frederickson;Jae-Young Koh;Ashley I. Bush;Ashley I. Bush

  2017
  Citations

• Rapid induction of Alzheimer A beta amyloid formation by zinc.

  Ashley I. Bush;Warren H. Pettingell;Gerd Multhaup;Marc D. Paradis

  1932
  Citations

• Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice

  Robert A Cherny;Craig S Atwood;Michel E Xilinas;Danielle N Gray

  1877
  Citations

• The metallobiology of Alzheimer's disease.

  Ashley I. Bush

  1548
  Citations

• The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

  Xudong Huang;Craig S. Atwood;Mariana A. Hartshorn;Gerd Multhaup

  1411
  Citations

• Oxidative stress in psychiatric disorders : evidence base and therapeutic implications

  Felicity Ng;Michael Berk;Michael Berk;Olivia Dean;Ashley I. Bush

  1324
  Citations

• Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis.

  C. S. Atwood;R. D. Moir;Xudong Huang;R. C. Scarpa

  1311
  Citations

• Metal-Protein Attenuation With Iodochlorhydroxyquin (Clioquinol) Targeting Aβ Amyloid Deposition and Toxicity in Alzheimer Disease: A Pilot Phase 2 Clinical Trial

  Craig W Ritchie;Ashley I Bush;Andrew J Mackinnon;Steve Macfarlane

  1230
  Citations

• Connecting copper and cancer: from transition metal signalling to metalloplasia.

  Eva J Ge;Ashley I Bush;Angela Casini;Paul A Cobine

  1204
  Citations

• The Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging: Methodology and baseline characteristics of 1112 individuals recruited for a longitudinal study of Alzheimer's disease

  Kathryn A Ellis;Ashley I Bush;David Darby;Daniela De Fazio

  1187
  Citations

• Cu(II) Potentiation of Alzheimer Aβ Neurotoxicity CORRELATION WITH CELL-FREE HYDROGEN PEROXIDE PRODUCTION AND METAL REDUCTION

  Xudong Huang;Math P. Cuajungco;Craig S. Atwood;Mariana A. Hartshorn

  1021
  Citations

• Metals and neuroscience.

  Ashley I Bush

  952
  Citations

• Zinc in the physiology and pathology of the CNS.

  Stefano L. Sensi;Pierre Paoletti;Ashley I. Bush;Ashley I. Bush;Israel Sekler

  874
  Citations

• Safety, efficacy, and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial

  Lars Lannfelt;Kaj Blennow;Henrik Zetterberg;Stellan Batsman

  850
  Citations

• Alzheimer's Disease Amyloid-β Binds Copper and Zinc to Generate an Allosterically Ordered Membrane-penetrating Structure Containing Superoxide Dismutase-like Subunits

  Cyril C. Curtain;Feda Ali;Irene Volitakis;Robert A. Cherny

  842
  Citations

• Characterization of copper interactions with alzheimer amyloid beta peptides: identification of an attomolar-affinity copper binding site on amyloid beta1-42.

  Craig S. Atwood;Richard C. Scarpa;Xudong Huang;Robert D. Moir

  811
  Citations

• Metals in Alzheimer's and Parkinson's Diseases

  Kevin J Barnham;Ashley I Bush;Ashley I Bush

  791
  Citations