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Myron I. Cybulsky

Myron I. Cybulsky

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
34408
World Ranking
6115
National Ranking
219

Overview

Myron I. Cybulsky is affiliated with the University Health Network in Canada. Their research primarily focuses on immunology, microbiology, and medicine, with additional work in biochemistry, genetics, and molecular biology. The subfields of their studies include immunology, molecular biology, infectious diseases, oncology, and pulmonary and respiratory medicine.

The scientist's main research topics are centered around atherosclerosis and cardiovascular diseases, immune cells in cancer, single-cell and spatial transcriptomics, SARS-CoV-2 detection and testing, SARS-CoV-2 and COVID-19 research, neutrophil, myeloperoxidase and oxidative mechanisms, and immune response and inflammation.

Their recent publications span several well-known scientific journals with diverse research areas:

  • Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles, 2022, Science Immunology
  • Meta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas, 2020, Circulation Research
  • Colony stimulating factor-1 producing endothelial cells and mesenchymal stromal cells maintain monocytes within a perivascular bone marrow niche, 2022, Immunity
  • Anti-Inflammatory Actions of Soluble Ninjurin-1 Ameliorate Atherosclerosis, 2020, Circulation
  • Comparison of SARS-CoV-2 indirect and direct RT-qPCR detection methods, 2021, Virology Journal

Frequent co-authors collaborating with Cybulsky include Sharon J. Hyduk, Corey A. Scipione, Chanele K. Polenz, Clinton S. Robbins, and Marwan G. Althagafi.

The scientist has consistently published in several prominent venues, including:

  • Arteriosclerosis Thrombosis and Vascular Biology
  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS ONE
  • Circulation Research

Cybulsky's body of work reflects an integration of immunological mechanisms, cellular biology, and disease pathology with particular emphasis on cardiovascular diseases and immune cell behavior in cancer and infection contexts.

Best Publications

  • Getting to the site of inflammation: the leukocyte adhesion cascade updated

    Klaus Ley;Carlo Laudanna;Myron I. Cybulsky;Sussan Nourshargh

  • Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis.

    Myron I. Cybulsky;Michael A. Gimbrone

  • A major role for VCAM-1, but not ICAM-1, in early atherosclerosis

    Myron I. Cybulsky;Kaeko Iiyama;Hongmei Li;Suning Zhu

  • Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells.

    N Kume;M I Cybulsky;M A Gimbrone

  • NF-κB: pivotal mediator or innocent bystander in atherogenesis?

    Tucker Collins;Myron I. Cybulsky

  • An atherogenic diet rapidly induces VCAM-1, a cytokine-regulatable mononuclear leukocyte adhesion molecule, in rabbit aortic endothelium.

    H. Li;M. I. Cybulsky;Michael Anthony Gimbrone;Peter Libby

  • Patterns of Vascular Cell Adhesion Molecule-1 and Intercellular Adhesion Molecule-1 Expression in Rabbit and Mouse Atherosclerotic Lesions and at Sites Predisposed to Lesion Formation

    Kaeko Iiyama;Leena Hajra;Motoi Iiyama;Hongmei Li

  • The NF-kappa B signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation.

    Leena Hajra;Andrew I. Evans;Mian Chen;Sharon J. Hyduk

  • The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells.

    R De Caterina;M I Cybulsky;S K Clinton;M A Gimbrone

  • Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction

    Sarah A. Dick;Jillian A. Macklin;Sara Nejat;Abdul Momen

  • Eosinophil recruitment to the lung in a murine model of allergic inflammation. The role of T cells, chemokines, and adhesion receptors.

    Jose Angel Gonzalo;Clare M. Lloyd;Leonor Kremer;Elizabeth Finger

  • Expression of ICAM-1 and VCAM-1 and Monocyte Adherence in Arteries Exposed to Altered Shear Stress

    Piyal L. Walpola;Avrum I. Gotlieb;Myron I. Cybulsky;B. Lowell Langille

  • Cytokine-activated human endothelial monolayers support enhanced neutrophil transmigration via a mechanism involving both endothelial-leukocyte adhesion molecule-1 and intercellular adhesion molecule-1.

    Francis W. Luscinskas;Myron I. Cybulsky;Jeanne Marie Kiely;Christopher S. Peckins

  • MicroRNA-146 represses endothelial activation by inhibiting pro-inflammatory pathways

    Henry S. Cheng;Nirojini Sivachandran;Andrew Lau;Emilie Boudreau

  • Targeted disruption of the murine VCAM1 gene: essential role of VCAM-1 in chorioallantoic fusion and placentation.

    Geoffrey C. Gurtner;Vannessa Davis;Hongmei Li;Michael J. McCoy

  • High-level expression of Egr-1 and Egr-1-inducible genes in mouse and human atherosclerosis.

    Timothy A. McCaffrey;Chenzhong Fu;Baoheng Du;Sukru Eksinar

  • Resident Intimal Dendritic Cells Accumulate Lipid and Contribute to the Initiation of Atherosclerosis

    Kim E. Paulson;Su-Ning Zhu;Mian Chen;Sabrina Nurmohamed

  • Low-grade chronic inflammation in regions of the normal mouse arterial intima predisposed to atherosclerosis

    Jenny Jongstra-Bilen;Mehran Haidari;Mehran Haidari;Su Ning Zhu;Su Ning Zhu;Mian Chen;Mian Chen

  • Sustained activation of vascular cells and leukocytes in the rabbit aorta after balloon injury.

    H Tanaka;G K Sukhova;S J Swanson;S K Clinton

  • Effect of granulocyte depletion in a ventilated surfactant-depleted lung.

    T. Kawano;S. Mori;M. Cybulsky;R. Burger

Frequent Co-Authors

Michael A. Gimbrone
Michael A. Gimbrone Brigham and Women's Hospital
Tucker Collins
Tucker Collins Boston Children's Hospital
Peter Libby
Peter Libby Brigham and Women's Hospital
Thomas K. Waddell
Thomas K. Waddell University Health Network
Philip A. Marsden
Philip A. Marsden University of Toronto
Tony Mazzulli
Tony Mazzulli University Health Network
James R. Woodgett
James R. Woodgett Lunenfeld-Tanenbaum Research Institute
Andras Kapus
Andras Kapus University of Toronto
Babak Razani
Babak Razani University of Pittsburgh
Francis W. Luscinskas
Francis W. Luscinskas Brigham and Women's Hospital

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