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Biology and Biochemistry

D-Index
85
Citations
29308
World Ranking
3121
National Ranking
30

Overview

Ronen Alon is affiliated with the Weizmann Institute of Science in Israel. Their research focuses primarily on immunology and microbiology, with significant contributions in medicine as well. The scientist's work spans various subfields, including immunology, oncology, molecular biology, immunology and allergy, and cell biology.

Their research topics encompass a broad range of immunological and cellular mechanisms, with emphasis on:

  • Immunotherapy and immune responses
  • Immune response and inflammation
  • T-cell and B-cell immunology
  • Cell adhesion molecules research
  • CAR-T cell therapy research
  • Immune cell function and interaction
  • Neutrophil, myeloperoxidase and oxidative mechanisms

Ronen Alon has contributed to several notable academic publications. Frequently, their research appears in these venues:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • arXiv (Cornell University)
  • Nature Communications

Recent published papers include:

  • "Leukocyte trafficking to the lungs and beyond: lessons from influenza for COVID-19" (2020), published in Nature reviews. Immunology
  • "Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling" (2020), published in Nature Communications
  • "β2 Integrin Signaling Cascade in Neutrophils: More Than a Single Function" (2021), published in Frontiers in Immunology
  • "Live imaging of chromatin distribution reveals novel principles of nuclear architecture and chromatin compartmentalization" (2021), published in Science Advances
  • "The magnitude of LFA-1/ICAM-1 forces fine-tune TCR-triggered T cell activation" (2022), published in Science Advances

Collaborative research is a part of Alon's work, involving frequent coauthors such as:

  • Francesco Roncato
  • Sara W. Feigelson
  • Stav Kozlovski
  • Ofer Regev
  • Nehora Levi

Best Publications

  • Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4

    Amnon Peled;Isabelle Petit;Orit Kollet;Michal Magid

  • Immune cell migration in inflammation: present and future therapeutic targets

    Andrew D Luster;Ronen Alon;Ulrich H von Andrian

  • Leukocyte migration into inflamed tissues.

    Sussan Nourshargh;Ronen Alon

  • The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice.

    Amnon Peled;Orit Kollet;Tanya Ponomaryov;Isabelle Petit

  • The integrin VLA-4 supports tethering and rolling in flow on VCAM-1.

    Ronen Alon;Paul D. Kassner;Michelle Woldemar Carr;Erik B. Finger

  • ICAM-1 regulates neutrophil adhesion and transcellular migration of TNF-α-activated vascular endothelium under flow

    Lin Yang;Richard M. Froio;Richard M. Froio;Richard M. Froio;Tracey E. Sciuto;Tracey E. Sciuto;Tracey E. Sciuto;Ann M. Dvorak;Ann M. Dvorak;Ann M. Dvorak

  • Lifetime of the P-selectin-carbohydrate bond and its response to tensile force in hydrodynamic flow.

    Ronen Alon;Daniel A. Hammer;Timothy A. Springer

  • The chemokine SDF-1 stimulates integrin-mediated arrest of CD34+ cells on vascular endothelium under shear flow

    Amnon Peled;Valentin Grabovsky;Liliana Habler;Judith Sandbank

  • DC-SIGN-ICAM-2 interaction mediates dendritic cell trafficking

    T.B.H. Geijtenbeek;D.J.E.B. Krooshoop;D.A. Bleijs;S.J. van Vliet

  • CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrow.

    Abraham Avigdor;Polina Goichberg;Shoham Shivtiel;Ayelet Dar

  • Adhesion through L-selectin requires a threshold hydrodynamic shear

    Erik B. Finger;Kamal D. Purl;Ronen Alon;Michael B. Lawrence

  • Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines.

    Revital Shamri;Valentin Grabovsky;Jean-Marc Gauguet;Sara Feigelson

  • Shear forces promote lymphocyte migration across vascular endothelium bearing apical chemokines.

    Guy Cinamon;Vera Shinder;Ronen Alon

  • The Kinetics of L-selectin Tethers and the Mechanics of Selectin-mediated Rolling

    Ronen Alon;Shuqi Chen;Kamal D. Puri;Erik B. Finger

  • Subsecond Induction of α4 Integrin Clustering by Immobilized Chemokines Stimulates Leukocyte Tethering and Rolling on Endothelial Vascular Cell Adhesion Molecule 1 under Flow Conditions

    Valentin Grabovsky;Sara Feigelson;Chun Chen;Diederik A. Bleijs

  • Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces.

    Eilon Woolf;Irina Grigorova;Adi Sagiv;Valentin Grabovsky

  • Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cells

    Ronen Alon;Michael L. Dustin

  • Heparin is an adhesive ligand for the leukocyte integrin Mac-1 (CD11b/CD1).

    Michael S. Diamond;Ronen Alon;Charles A. Parkos;Mark T. Quinn

  • Galectin-8 binding to integrins inhibits cell adhesion and induces apoptosis

    Yaron R. Hadari;Rinat Arbel-Goren;Yifat Levy;Avraham Amsterdam

  • DC-SIGN-ICAM-2 interaction mediates dendritic cell trafficking

    T.B. Geijtenbeek;D.J.E.B. Krooshoop;D.A. Bleijs;S. van Vliet

Frequent Co-Authors

Rami Hershkoviz
Rami Hershkoviz Tel Aviv University
Timothy A. Springer
Timothy A. Springer Boston Children's Hospital
Ofer Lider
Ofer Lider Weizmann Institute of Science
Tsvee Lapidot
Tsvee Lapidot Weizmann Institute of Science
Amnon Peled
Amnon Peled Hebrew University of Jerusalem
Amos Etzioni
Amos Etzioni Technion – Israel Institute of Technology
Orit Kollet
Orit Kollet Weizmann Institute of Science
Edward A. Bayer
Edward A. Bayer Weizmann Institute of Science
Meir Wilchek
Meir Wilchek Weizmann Institute of Science
Francis W. Luscinskas
Francis W. Luscinskas Brigham and Women's Hospital

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