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D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
12187
World Ranking
12014
National Ranking
5154

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Robert Sackstein is affiliated with Florida International University in the United States. Their research spans multiple fields with a strong emphasis on medicine, biochemistry, genetics, molecular biology, immunology, and microbiology. The scientist has contributed notably to subfields such as molecular biology, immunology, oncology, surgery, and genetics.

The research topics that Robert Sackstein has focused on include glycosylation and glycoproteins, mesenchymal stem cell research, immunotherapy and immune responses, galectins and cancer biology, immune cell function and interaction, ubiquitin and proteasome pathways, as well as tissue engineering and regenerative medicine.

Frequent publication venues for their work include Cytotherapy, Cancer Research, FEBS Journal, Frontiers in Immunology, and the Journal of Biological Chemistry. The scientist has collaborated regularly with several co-authors, among whom are Kevin Brown Chandler, José M. Moraleda, Evan Ales, Barbara Richichi, and Miguel Blanquer.

Notable recent papers authored or co-authored by Robert Sackstein and colleagues are:

  • ABO blood group antigens and differential glycan expression: Perspective on the evolution of common human enzyme deficiencies, 2022, published in iScience
  • The schizophrenia risk locus in SLC39A8 alters brain metal transport and plasma glycosylation, 2020, published in Scientific Reports
  • Recent advances on smart glycoconjugate vaccines in infections and cancer, 2021, published in FEBS Journal
  • Emerging glyco-based strategies to steer immune responses, 2021, published in FEBS Journal
  • Defibrotide inhibits donor leucocyte-endothelial interactions and protects against acute graft-versus-host disease, 2020, published in Journal of Cellular and Molecular Medicine

Robert Sackstein is listed as a member of the Association of American Physicians, an affiliation indicating involvement in professional medical communities.

Best Publications

  • Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia.

    Kalindi Parmar;Peter Mauch;Jo-Anne Vergilio;Robert Sackstein

  • Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone

    Robert Sackstein;Jasmeen S Merzaban;Derek W Cain;Nilesh M Dagia

  • Combined histocompatibility leukocyte antigen-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: the induction of allograft tolerance through mixed lymphohematopoietic chimerism.

    T R Spitzer;F Delmonico;N Tolkoff-Rubin;S McAfee

  • CD44 is a major E-selectin ligand on human hematopoietic progenitor cells.

    Charles J. Dimitroff;Charles J. Dimitroff;Jack Y. Lee;Jack Y. Lee;Shahin Rafii;Robert C. Fuhlbrigge;Robert C. Fuhlbrigge

  • Mixed lymphohaemopoietic chimerism and graft-ver suslymphoma effects after non-myeloablative therapy and HLA-mismatched bone-marrow transplantation

    Megan Sykes;Frederic Preffer;Steven McAfee;Susan L Saidman

  • Intentional induction of mixed chimerism and achievement of antitumor responses after nonmyeloablative conditioning therapy and HLA-matched donor bone marrow transplantation for refractory hematologic malignancies.

    Thomas R. Spitzer;Steven McAfee;Robert Sackstein;Christine Colby

  • Induction of kidney allograft tolerance after transient lymphohematopoietic chimerism in patients with multiple myeloma and end-stage renal disease.

    Bühler Lh;Spitzer Tr;Sykes M;Sachs Dh

  • High-dose porcine hematopoietic cell transplantation combined with CD40 ligand blockade in baboons prevents an induced anti-pig humoral response.

    L. Bühler;M. Awwad;M. Basker;S. Gojo

  • Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice.

    A. J. Gerard Jansen;Emma C. Josefsson;Viktoria Rumjantseva;Qiyong Peter Liu

  • Bone vascular niche E-selectin induces mesenchymal-epithelial transition and Wnt activation in cancer cells to promote bone metastasis.

    Mark Esposito;Nandini Mondal;Todd M. Greco;Yong Wei

  • T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy

    Robert Sackstein;Tobias Schatton;Steven R Barthel;Steven R Barthel

  • Impact of prophylactic donor leukocyte infusions on mixed chimerism, graft-versus-host disease, and antitumor response in patients with advanced hematologic malignancies treated with nonmyeloablative conditioning and allogeneic bone marrow transplantation.

    Bimalangshu R Dey;Steven McAfee;Christine Colby;Robert Sackstein

  • Coagulation and thrombotic disorders associated with pig organ and hematopoietic cell transplantation in nonhuman primates.

    L. Bühler;M. Basker;I. P.J. Alwayn;C. Goepfert

  • The lymphocyte homing receptors: gatekeepers of the multistep paradigm

    Robert Sackstein

  • A distinct glycoform of CD44 is an L-selectin ligand on human hematopoietic cells.

    Charles J. Dimitroff;Jack Y. Lee;Robert C. Fuhlbrigge;Robert Sackstein

  • A major fraction of human bone marrow lymphocytes are Th2-like CD1d-reactive T cells that can suppress mixed lymphocyte responses.

    Mark A. Exley;Syed Muhammad Ali Tahir;Olivia Cheng;Angela Shaulov

  • Variant isoforms of CD44 are P- and L-selectin ligands on colon carcinoma cells

    William D. Hanley;Susan L. Napier;Monica M. Burdick;Ronald L. Schnaar

  • CD44 on LS174T colon carcinoma cells possesses E-selectin ligand activity

    William D. Hanley;Monica M. Burdick;Konstantinos Konstantopoulos;Robert Sackstein

  • SDF-1/CXCR4 and VLA-4 interaction regulates homing in Waldenstrom macroglobulinemia.

    Hai T. Ngo;Xavier Leleu;Jack Lee;Xiaoying Jia

  • The bone marrow is akin to skin: HCELL and the biology of hematopoietic stem cell homing.

    Robert Sackstein;Robert Sackstein

Frequent Co-Authors

David H. Sachs
David H. Sachs Columbia University
Megan Sykes
Megan Sykes Columbia University
Robert C. Fuhlbrigge
Robert C. Fuhlbrigge University of Colorado Anschutz Medical Campus
David K. C. Cooper
David K. C. Cooper University of Pittsburgh
Derrick J. Rossi
Derrick J. Rossi Harvard University
Jordan W. Smoller
Jordan W. Smoller Harvard University
Mark J. Daly
Mark J. Daly Massachusetts General Hospital
Frederic I. Preffer
Frederic I. Preffer Harvard University
Harvey R. Colten
Harvey R. Colten Washington University in St. Louis
Simon C. Robson
Simon C. Robson Beth Israel Deaconess Medical Center

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