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Overview

Steven P. Treon is affiliated with Harvard University in the United States and has contributed extensively to the field of medicine, with a focus on genetics, pathology and forensic medicine, immunology, hematology, and molecular biology. Their research encompasses various aspects of lymphoid neoplasms and leukemia, particularly chronic lymphocytic leukemia and lymphoma diagnosis and treatment.

The main topics covered in their work include:

  • Chronic Lymphocytic Leukemia Research
  • Lymphoma Diagnosis and Treatment
  • Immunodeficiency and Autoimmune Disorders
  • Chronic Myeloid Leukemia Treatments
  • Acute Lymphoblastic Leukemia Research
  • Viral-associated Cancers and Disorders
  • Gastrointestinal Tumor Research and Treatment

Steven P. Treon's frequent co-authors include Jorge J. Castillo, Shayna Sarosiek, Zachary R. Hunter, Maria Luisa Guerrera, and Christopher J. Patterson.

Publications by Treon have appeared predominantly in the following venues:

  • Blood
  • Blood Advances
  • Seminars in Hematology
  • Journal of Clinical Oncology
  • Clinical Lymphoma Myeloma & Leukemia

Recent papers authored or co-authored by Steven P. Treon include:

  • The International Consensus Classification of Mature Lymphoid Neoplasms: a report from the Clinical Advisory Committee, 2022, Blood
  • The BTK inhibitor ibrutinib may protect against pulmonary injury in COVID-19-infected patients, 2020, Blood
  • Genomic Landscape of Waldenström Macroglobulinemia and Its Impact on Treatment Strategies, 2020, Journal of Clinical Oncology
  • Genomic profiling for clinical decision making in lymphoid neoplasms, 2022, Blood
  • Long-Term Follow-Up of Ibrutinib Monotherapy in Symptomatic, Previously Treated Patients With Waldenström Macroglobulinemia, 2020, Journal of Clinical Oncology

The breadth of Steven P. Treon's work reflects an emphasis on hematological malignancies and their genetic and molecular underpinnings, contributing to clinical strategies and therapeutic approaches in these areas.

Best Publications

  • MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia

    Steven P. Treon;Lian Xu;Guang Yang;Yangsheng Zhou

  • Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy.

    Teru Hideshima;Dharminder Chauhan;Dharminder Chauhan;Yoshihito Shima;Yoshihito Shima;Noopur Raje;Noopur Raje

  • Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma.

    Faith E. Davies;Noopur Raje;Noopur Raje;Noopur Raje;Teru Hideshima;Teru Hideshima;Teru Hideshima;Suzanne Lentzsch;Suzanne Lentzsch;Suzanne Lentzsch

  • Clinicopathological definition of Waldenstrom's macroglobulinemia: Consensus panel recommendations from the Second International Workshop on Waldenstrom's Macroglobulinemia

    Roger G. Owen;Steven P. Treon;Ayad Al-Katib;Rafael Fonseca

  • Ibrutinib in Previously Treated Waldenström’s Macroglobulinemia

    Steven P. Treon;Christina K. Tripsas;Kirsten Meid;Diane Warren

  • Molecular sequelae of proteasome inhibition in human multiple myeloma cells

    Nicholas Mitsiades;Constantine S. Mitsiades;Vassiliki Poulaki;Dharminder Chauhan

  • Adherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: therapeutic applications.

    D Gupta;S P Treon;Y Shima;T Hideshima

  • Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications

    Nicholas Mitsiades;Constantine S. Mitsiades;Vassiliki Poulaki;Dharminder Chauhan

  • Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications.

    Constantine S Mitsiades;Nicholas Mitsiades;Vassiliki Poulaki;Robert Schlossman

  • IL-6 triggers cell growth via the Ras-dependent mitogen-activated protein kinase cascade.

    A Ogata;D Chauhan;G Teoh;S P Treon

  • The genomic landscape of Waldenström macroglobulinemia is characterized by highly recurring MYD88 and WHIM-like CXCR4 mutations, and small somatic deletions associated with B-cell lymphomagenesis

    Zachary R. Hunter;Lian Xu;Guang Yang;Yangsheng Zhou

  • TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: therapeutic applications

    Constantine S. Mitsiades;Steven P. Treon;Nicholas Mitsiades;Yoshihito Shima

  • Biologic sequelae of nuclear factor–κB blockade in multiple myeloma: therapeutic applications

    Nicholas Mitsiades;Constantine S. Mitsiades;Vassiliki Poulaki;Dharminder Chauhan

  • International prognostic scoring system for Waldenstrom macroglobulinemia

    Pierre Morel;Alain Duhamel;Paolo Gobbi;Meletios A. Dimopoulos

  • Molecular mechanisms whereby immunomodulatory drugs activate natural killer cells: clinical application.

    Toshiaki Hayashi;Teru Hideshima;Masaharu Akiyama;Klaus Podar

  • Prognostic markers and criteria to initiate therapy in Waldenstrom's macroglobulinemia: consensus panel recommendations from the Second International Workshop on Waldenstrom's Macroglobulinemia.

    Robert A. Kyle;Steven P. Treon;Raymond Alexanian;Bart Barlogie

  • Somatic mutations in MYD88 and CXCR4 are determinants of clinical presentation and overall survival in Waldenstrom macroglobulinemia.

    Steven P. Treon;Yang Cao;Lian Xu;Guang Yang

  • How I treat Waldenstrom macroglobulinemia

    Steven P. Treon

  • A mutation in MYD88 (L265P) supports the survival of lymphoplasmacytic cells by activation of Bruton tyrosine kinase in Waldenström macroglobulinemia.

    Guang Yang;Yangsheng Zhou;Xia Liu;Lian Xu

  • Elevated IL-17 produced by TH17 cells promotes myeloma cell growth and inhibits immune function in multiple myeloma.

    Rao H. Prabhala;Dheeraj Pelluru;Mariateresa Fulciniti;Harsha K. Prabhala

Frequent Co-Authors

Kenneth C. Anderson
Kenneth C. Anderson Harvard University
Irene M. Ghobrial
Irene M. Ghobrial Harvard University
Nikhil C. Munshi
Nikhil C. Munshi Harvard University
Xavier Leleu
Xavier Leleu Harvard University
Paul G. Richardson
Paul G. Richardson Harvard University
Teru Hideshima
Teru Hideshima Harvard University
Yu-Tzu Tai
Yu-Tzu Tai Harvard University
Dharminder Chauhan
Dharminder Chauhan Harvard University
Meletios A. Dimopoulos
Meletios A. Dimopoulos National and Kapodistrian University of Athens
Véronique Leblond
Véronique Leblond Sorbonne University

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