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Philippe I. H. Bastiaens

Philippe I. H. Bastiaens

D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
19475
World Ranking
7701
National Ranking
563

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Philippe I. H. Bastiaens is affiliated with the Max Planck Society in Germany and has contributed to multiple research fields predominantly within biochemistry, genetics, and molecular biology, along with intersections in medicine. Their work spans a range of subfields including molecular biology, oncology, cellular and molecular neuroscience, structural biology, and biomaterials.

The scientist's research interests focus notably on protein tyrosine phosphatases, axon guidance and neuronal signaling, HER2/EGFR mechanisms in cancer research, protein kinase regulation and GTPase signaling, advanced electron microscopy techniques and applications, lipid membrane structure and behavior, and supramolecular self-assembly in materials.

Recent publications by Philippe I. H. Bastiaens include the following papers:

  • Processing Temporal Growth Factor Patterns by an Epidermal Growth Factor Receptor Network Dynamically Established in Space (2020, Annual Review of Cell and Developmental Biology)
  • Growth factor-dependent ErbB vesicular dynamics couple receptor signaling to spatially and functionally distinct Erk pools (2021, Science Signaling)
  • A self-organized synthetic morphogenic liposome responds with shape changes to local light cues (2021, Nature Communications)
  • Ultrarapid cryo-arrest of living cells on a microscope enables multiscale imaging of out-of-equilibrium molecular patterns (2021, Science Advances)
  • The EGFR phosphatase RPTPγ is a redox-regulated suppressor of promigratory signaling (2023, The EMBO Journal)

Frequent coauthors collaborating with Philippe I. H. Bastiaens include Jan Huebinger, Angel Stanoev, Aneta Koseska, Malte Schmick, and Maitreyi S. Joshi.

The venues where this scientist often publishes include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Annual Review of Cell and Developmental Biology
  • Science Signaling
  • Nature Communications
  • The EMBO Journal

Philippe I. H. Bastiaens has been recognized as a Member of the European Molecular Biology Organization (EMBO).

Best Publications

  • An Acylation Cycle Regulates Localization and Activity of Palmitoylated Ras Isoforms

    Oliver Rocks;Anna Peyker;Martin Kahms;Peter J. Verveer

  • Fluorescence lifetime imaging microscopy: spatial resolution of biochemical processes in the cell.

    Philippe I. H. Bastiaens;Anthony Squire

  • Protein analysis on a proteomic scale.

    Eric Phizicky;Philippe I. H. Bastiaens;Heng Zhu;Michael Snyder

  • Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate.

    Silvia D. M. Santos;Peter J. Verveer;Philippe I. H. Bastiaens

  • Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling

    Gunther Zimmermann;Björn Papke;Shehab Ismail;Nachiket Vartak

  • Imaging biochemistry inside cells

    Fred S. Wouters;Peter J. Verveer;Philippe I.H. Bastiaens

  • Imaging Sites of Receptor Dephosphorylation by PTP1B on the Surface of the Endoplasmic Reticulum

    Fawaz G. Haj;Peter J. Verveer;Anthony Squire;Benjamin G. Neel

  • The Palmitoylation Machinery Is a Spatially Organizing System for Peripheral Membrane Proteins

    Oliver Rocks;Marc Gerauer;Nachiket Vartak;Sebastian Koch

  • Small-molecule inhibition of APT1 affects Ras localization and signaling

    Frank J Dekker;Oliver Rocks;Nachiket Vartak;Sascha Menninger

  • PKCα regulates β1 integrin‐dependent cell motility through association and control of integrin traffic

    Tony Ng;David Shima;Anthony Squire;Philippe I.H. Bastiaens

  • Imaging Protein Kinase Cα Activation in Cells

    Tony Ng;Anthony Squire;Gurdip Hansra;Frederic Bornancin

  • Spatial Coordination of Spindle Assembly by Chromosome-Mediated Signaling Gradients

    Maïwen Caudron;Gertrude Bunt;Philippe Bastiaens;Eric Karsenti;Eric Karsenti

  • Ezrin is a downstream effector of trafficking PKC-integrin complexes involved in the control of cell motility.

    Tony Ng;Tony Ng;Maddy Parsons;William E. Hughes;James Monypenny

  • The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins

    Anchal Chandra;Hernãin E. Grecco;Venkat Pisupati;David Perera

  • Imaging the intracellular trafficking and state of the AB5 quaternary structure of cholera toxin.

    Philippe I. H. Bastiaens;Irina V. Majoul;Peter J. Verveer;Hans-Dieter Söling

  • Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo

    Shehab A Ismail;Yong-Xiang Chen;Alexandra Rusinova;Anchal Chandra

  • Global analysis of fluorescence lifetime imaging microscopy data.

    Peter J. Verveer;Anthony Squire;Philippe I.H. Bastiaens

  • EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagation.

    Andrew R. Reynolds;Christian Tischer;Peter J. Verveer;Oliver Rocks

  • Spatial regulation of Fus3 MAP kinase activity through a reaction-diffusion mechanism in yeast pheromone signalling

    Celine I. Maeder;Mark A. Hink;Ali Kinkhabwala;Reinhard Mayr

  • Imaging FRET between spectrally similar GFP molecules in single cells.

    Ailsa G. Harpur;Fred S. Wouters;Philippe I.H. Bastiaens

Frequent Co-Authors

Herbert Waldmann
Herbert Waldmann Max Planck Society
Antonie J. W. G. Visser
Antonie J. W. G. Visser Wageningen University & Research
Thomas M. Jovin
Thomas M. Jovin Max Planck Society
Alfred Wittinghofer
Alfred Wittinghofer Max Planck Society
Rainer Pepperkok
Rainer Pepperkok European Molecular Biology Laboratory
Karel W. A. Wirtz
Karel W. A. Wirtz Utrecht University
Roger S. Goody
Roger S. Goody Max Planck Society
Christof M. Niemeyer
Christof M. Niemeyer Karlsruhe Institute of Technology
Jan Willem Borst
Jan Willem Borst Wageningen University & Research
Eric Karsenti
Eric Karsenti École Normale Supérieure

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