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Biology and Biochemistry
Germany
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
90
Citations
27036
World Ranking
2451
National Ranking
174

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Germany Leader Award

Overview

Rainer Pepperkok is affiliated with the European Molecular Biology Laboratory in Germany. Their research contributions span across the fields of Biochemistry, Genetics, and Molecular Biology as well as Medicine, with a particular focus on molecular and cellular processes.

The scientist has contributed to multiple subfields, including Molecular Biology, Pulmonary and Respiratory Medicine, Cell Biology, Biophysics, and Genetics. Their main research topics encompass Cystic Fibrosis Research Advances, Cell Image Analysis Techniques, Advanced Biosensing and Bioanalysis Techniques, Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis, Inhalation and Respiratory Drug Delivery, Cellular Transport and Secretion, and Microtubule and Mitosis Dynamics.

Frequent publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Nature Communications
  • The Journal of Cell Biology
  • Atherosclerosis

The scientist has collaborated regularly with several coauthors, including:

  • Christian Tischer
  • Beate Neumann
  • Aliaksandr Halavatyi
  • Muzamil Majid Khan
  • Joanna Zukowska

Notable recent papers by Rainer Pepperkok include:

  • "Priorities for ocean microbiome research," 2022, Nature Microbiology
  • "An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in ex vivo human precision-cut lung slices," 2020, European Respiratory Journal
  • "Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy," 2024, Nature Communications
  • "BigDataProcessor2: a free and open-source Fiji plugin for inspection and processing of TB sized image data," 2021, Bioinformatics
  • "Regulation of the COPII secretory machinery via focal adhesions and extracellular matrix signaling," 2022, The Journal of Cell Biology

Best Publications

  • Cyclin A is required at two points in the human cell cycle.

    M. Pagano;R. Pepperkok;F. Verde;W. Ansorge

  • RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

    Carsten Doil;Niels Mailand;Simon Bekker-Jensen;Patrice Menard

  • Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes

    Beate Neumann;Thomas Walter;Jean Karim Hériché;Jutta Bulkescher

  • Spectral imaging and its applications in live cell microscopy

    Timo Zimmermann;Jens Rietdorf;Rainer Pepperkok

  • Visualization of ER-to-Golgi Transport in Living Cells Reveals a Sequential Mode of Action for COPII and COPI

    Suzie J. Scales;Rainer Pepperkok;Thomas E. Kreis

  • Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment

    Simon Reiss;Ilka Rebhan;Perdita Backes;Ines Romero-Brey

  • High-throughput fluorescence microscopy for systems biology

    Rainer Pepperkok;Jan Ellenberg

  • Transcription-dependent colocalization of the U1, U2, U4/U6, and U5 snRNPs in coiled bodies

    M Carmo-Fonseca;R Pepperkok;MT Carvalho;AI Lamond

  • High-throughput RNAi screening by time-lapse imaging of live human cells.

    Beate Neumann;Michael Held;Urban Liebel;Holger Erfle

  • Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing

    Jeremy C. Simpson;Ruth Wellenreuther;Annemarie Poustka;Rainer Pepperkok

  • Evidence for a COP-I-independent transport route from the Golgi complex to the endoplasmic reticulum

    A Girod;B Storrie;J C Simpson;L Johannes

  • The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells

    Geraldine M. Twamley-Stein;Rainer Pepperkok;Wilhelm Ansorge;Sara A. Courtneidge

  • Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts

    Michele Pagano;Rainer Pepperkok;Jiri Lukas;Veronique Baldin

  • Molecular recognition of a single sphingolipid species by a protein’s transmembrane domain

    F.-Xabier Contreras;Andreas M. Ernst;Per Haberkant;Per Haberkant;Patrik Björkholm;Patrik Björkholm

  • β-COP is essential for biosynthetic membrane transport from the endoplasmic reticulum to the Golgi complex in vivo

    R. Pepperkok;J. Scheel;H. Horstmann;H.P. Hauri

  • Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells

    Oliver J Gruss;Malte Wittmann;Hideki Yokoyama;Rainer Pepperkok

  • Partitioning of the Golgi Apparatus during Mitosis in Living HeLa Cells

    David T. Shima;Kasturi Haldar;Rainer Pepperkok;Rose Watson

  • Mutations affecting the secretory COPII coat component SEC23B cause congenital dyserythropoietic anemia type II.

    Klaus Schwarz;Klaus Schwarz;Achille Iolascon;Fatima Verissimo;Nikolaus S Trede;Nikolaus S Trede

  • Inhibition of Intracellular Cholesterol Transport Alters Presenilin Localization and Amyloid Precursor Protein Processing in Neuronal Cells

    Heiko Runz;Jens Rietdorf;Inge Tomic;Marina de Bernard

  • Spectral imaging and linear un-mixing enables improved FRET efficiency with a novel GFP2–YFP FRET pair

    Timo Zimmermann;Jens Rietdorf;Andreas Girod;Virginie Georget

Frequent Co-Authors

Jeremy C. Simpson
Jeremy C. Simpson University College Dublin
Stefan Wiemann
Stefan Wiemann German Cancer Research Center
Jan Ellenberg
Jan Ellenberg European Bioinformatics Institute
Heiko Runz
Heiko Runz Biogen (United States)
Thomas E. Kreis
Thomas E. Kreis University of Geneva
Wilhelm Ansorge
Wilhelm Ansorge École Polytechnique Fédérale de Lausanne
David J. Stephens
David J. Stephens University of Bristol
Peer Bork
Peer Bork European Molecular Biology Laboratory
Roland Eils
Roland Eils Charité - University Medicine Berlin
Annemarie Poustka
Annemarie Poustka German Cancer Research Center

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