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Wieland B. Huttner

Wieland B. Huttner

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Biology and Biochemistry
Germany
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
130
Citations
55981
World Ranking
408
National Ranking
27

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Germany Leader Award
  • 2025 - Research.com Biology and Biochemistry in Germany Leader Award
  • 2023 - Research.com Biology and Biochemistry in Germany Leader Award
  • 2001 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Neurosciences
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Wieland B. Huttner is affiliated with the Max Planck Society in Germany and focuses research efforts on the fields of Biochemistry, Genetics and Molecular Biology, as well as Neuroscience. Their work spans several subfields including Molecular Biology, Developmental Neuroscience, Genetics, Cellular and Molecular Neuroscience, and Pediatrics, Perinatology and Child Health.

The scientist's primary research topics include:

  • Neurogenesis and neuroplasticity mechanisms
  • Pluripotent Stem Cells Research
  • Genetics and Neurodevelopmental Disorders
  • Epigenetics and DNA Methylation
  • RNA Research and Splicing
  • Congenital heart defects research
  • MicroRNA in disease regulation

Recent peer-reviewed papers authored or co-authored by Wieland B. Huttner cover diverse aspects of neocortex development and evolutionary biology:

  • "Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals," 2022, published in Science
  • "Human-specific ARHGAP11B increases size and folding of primate neocortex in the fetal marmoset," 2020, published in Science
  • "Metabolic Regulation of Neocortical Expansion in Development and Evolution," 2020, published in Neuron
  • "Basal Progenitor Morphology and Neocortex Evolution," 2020, published in Trends in Neurosciences
  • "Expression of human-specific ARHGAP11B in mice leads to neocortex expansion and increased memory flexibility," 2021, published in The EMBO Journal

Wieland B. Huttner regularly collaborates with researchers including Michael Heide, Takashi Namba, Lei Xing, Samir Vaid, and Jula Peters. These frequent co-authors have contributed to studies across neuroscience and molecular biology topics relating to brain development.

Publication venues where Wieland has most frequently published include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Cell and Developmental Biology
  • Journal of Visualized Experiments
  • Science
  • Science Advances

Recognition for Wieland B. Huttner's scientific contributions includes election to the German National Academy of Sciences Leopoldina in 2001, specifically within the neurosciences category, and membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • The cell biology of neurogenesis.

    Magdalena Götz;Wieland B. Huttner

  • Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation.

    W B Huttner;W Schiebler;P Greengard;P De Camilli

  • Neurons arise in the basal neuroepithelium of the early mammalian telencephalon: A major site of neurogenesis

    Wulf Haubensak;Alessio Attardo;Winfried Denk;Wieland B. Huttner

  • Human cerebral organoids recapitulate gene expression programs of fetal neocortex development

    J. Gray Camp;Farhath Badsha;Marta Florio;Sabina Kanton

  • The Cell Biology of Neurogenesis: Toward an Understanding of the Development and Evolution of the Neocortex

    Elena Taverna;Magdalena Götz;Wieland B. Huttner

  • OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling

    Simone A Fietz;Iva Kelava;Johannes Vogt;Michaela Wilsch-Bräuninger

  • Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells

    Anja Weigmann;Denis Corbeil;Andrea Hellwig;Wieland B. Huttner

  • Synapsin I (Protein I), a nerve terminal-specific phosphoprotein. II. Its specific association with synaptic vesicles demonstrated by immunocytochemistry in agarose-embedded synaptosomes.

    P De Camilli;S M Harris;W B Huttner;P Greengard

  • Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid

    Anne Schmidt;Anne Schmidt;Michael Wolde;Christoph Thiele;Christoph Thiele;Werner Fest

  • Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles

    Christoph Thiele;Christoph Thiele;Matthew J. Hannah;Matthew J. Hannah;Matthew J. Hannah;Falk Fahrenholz;Wieland B. Huttner;Wieland B. Huttner

  • Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion

    Marta Florio;Mareike Albert;Elena Taverna;Takashi Namba

  • Neural progenitors, neurogenesis and the evolution of the neocortex

    Marta Florio;Wieland B. Huttner

  • Retention of prominin in microvilli reveals distinct cholesterol-based lipid micro-domains in the apical plasma membrane.

    Katja Röper;Denis Corbeil;Denis Corbeil;Wieland B. Huttner;Wieland B. Huttner

  • Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors.

    Christian Lange;Wieland B. Huttner;Federico Calegari

  • Organoid single-cell genomic atlas uncovers human-specific features of brain development

    Sabina Kanton;Michael James Boyle;Zhisong He;Zhisong He;Malgorzata Santel

  • Isolation of neural stem cells from the postnatal cerebellum.

    Audra Lee;Jessica D. Kessler;Tracy Ann Read;Constanze Kaiser

  • Release of extracellular membrane particles carrying the stem cell marker prominin-1 (cd133) from neural progenitors and other epithelial cells

    Denis Corbeil;Wieland B. Huttner;Anne-Marie Marzesco

  • The granin-(chromogranin/secretogranin) family

    Wieland B. Huttner;Hans Hermann Gerdes;Patrizia Rosa

  • The Human AC133 Hematopoietic Stem Cell Antigen Is also Expressed in Epithelial Cells and Targeted to Plasma Membrane Protrusions

    Denis Corbeil;Katja Röper;Andrea Hellwig;Manuela Tavian

  • Chlorate a potent inhibitor of protein sulfation in intact cells

    Patrick A. Baeuerle;Wieland B. Huttner

Frequent Co-Authors

Denis Corbeil
Denis Corbeil TU Dresden
Christoph Thiele
Christoph Thiele University of Bonn
Svante Pääbo
Svante Pääbo Max Planck Institute for Evolutionary Anthropology
Sharon A. Tooze
Sharon A. Tooze The Francis Crick Institute
Magdalena Götz
Magdalena Götz Ludwig-Maximilians-Universität München
Francis A. Barr
Francis A. Barr University of Oxford
Patrick A. Baeuerle
Patrick A. Baeuerle Cullinan Oncology, Inc.
Wolfgang Enard
Wolfgang Enard Ludwig-Maximilians-Universität München
Christof Niehrs
Christof Niehrs German Cancer Research Center

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