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Neuroscience

D-Index
108
Citations
59778
World Ranking
571
National Ranking
323

Research.com Recognitions

  • 2008 - Member of the National Academy of Medicine (NAM)

Overview

Arnold R. Kriegstein is affiliated with the University of California, San Francisco in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Neuroscience, with a strong focus on Molecular Biology, Developmental Neuroscience, and Neurology. Their work also intersects areas such as Cancer Research and Cellular and Molecular Neuroscience.

The scientist's research topics include single-cell and spatial transcriptomics, mechanisms of neurogenesis and neuroplasticity, RNA research and splicing, epigenetics and DNA methylation, neuroinflammation and neurodegeneration mechanisms, pluripotent stem cells research, and microRNA involvement in disease regulation.

Prominent recent papers document a range of investigative efforts:

  • Cell stress in cortical organoids impairs molecular subtype specification (2020, Nature)
  • Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies (2020, Cell)
  • Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia (2021, Nature Neuroscience)
  • Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma (2020, Cell stem cell)
  • An atlas of cortical arealization identifies dynamic molecular signatures (2021, Nature)

The scientist collaborates frequently with researchers such as Aparna Bhaduri, Li Wang, Tomasz J. Nowakowski, Madeline G. Andrews, and Eric J. Huang. These collaborations have contributed to a substantial body of work across multiple publications.

Key venues where their work has appeared include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Cell
  • Cell stem cell
  • Science

Arnold R. Kriegstein was recognized by election as a Member of the National Academy of Medicine in 2008.

Best Publications

  • The glial nature of embryonic and adult neural stem cells

    Arnold Kriegstein;Arturo Alvarez-Buylla

  • Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases

    Stephen C Noctor;Verónica Martínez-Cerdeño;Lidija Ivic;Arnold R Kriegstein

  • Neurons derived from radial glial cells establish radial units in neocortex

    Stephen C. Noctor;Alexander C. Flint;Tamily A. Weissman;Ryan S. Dammerman

  • Glutamate neurotoxicity in cortical cell culture

    Dennis W. Choi;Margaret Maulucci-Gedde;Arnold R. Kriegstein

  • Is there more to gaba than synaptic inhibition

    David F. Owens;Arnold R. Kriegstein

  • Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

    Shawn F. Sorrells;Mercedes F. Paredes;Arantxa Cebrian-Silla;Kadellyn Sandoval

  • Neurogenic radial glia in the outer subventricular zone of human neocortex

    David V. Hansen;Jan H. Lui;Philip R. L. Parker;Arnold R. Kriegstein

  • Development and Evolution of the Human Neocortex

    Jan H. Lui;David V. Hansen;Arnold R. Kriegstein

  • GABA and glutamate depolarize cortical progenitor cells and inhibit DNA synthesis

    Joseph J. LoTurco;David F. Owens;Mark J.S. Heath;Marion B.E. Davis

  • Whole cell recording from neurons in slices of reptilian and mammalian cerebral cortex.

    Mark G. Blanton;Joseph J. Lo Turco;Arnold R. Kriegstein

  • Excitatory GABA Responses in Embryonic and Neonatal Cortical Slices Demonstrated by Gramicidin Perforated-Patch Recordings and Calcium Imaging

    David F. Owens;Leslie H. Boyce;Marion B. E. Davis;Arnold R. Kriegstein

  • Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex.

    Alex A Pollen;Tomasz J Nowakowski;Joe Shuga;Xiaohui Wang

  • Spatiotemporal gene expression trajectories reveal developmental hierarchies of the human cortex

    Tomasz J. Nowakowski;Aparna Bhaduri;Alex A. Pollen;Beatriz Alvarado

  • Single-cell genomics identifies cell type-specific molecular changes in autism.

    Dmitry Velmeshev;Lucas Schirmer;Lucas Schirmer;Diane Jung;Maximilian Haeussler

  • Patterns of neuronal migration in the embryonic cortex

    Arnold R Kriegstein;Stephen C Noctor

  • Molecular Identity of Human Outer Radial Glia during Cortical Development

    Alex A. Pollen;Tomasz J. Nowakowski;Jiadong Chen;Hanna Retallack

  • The use of brain organoids to investigate neural development and disease

    Elizabeth Di Lullo;Arnold R. Kriegstein

  • Patterns of neural stem and progenitor cell division may underlie evolutionary cortical expansion

    Arnold Kriegstein;Stephen C Noctor;Veronica Martinez-Cerdeno

  • Developmental genetics of vertebrate glial–cell specification

    David H. Rowitch;Arnold R. Kriegstein

  • Dividing precursor cells of the embryonic cortical ventricular zone have morphological and molecular characteristics of radial glia.

    Stephen C. Noctor;Alexander C. Flint;Tamily A. Weissman;Winston S. Wong

  • ErratumDevelopment and Evolution of the Human Neocortex

    Jan H. Lui;David V. Hansen;Arnold R. Kriegstein

Frequent Co-Authors

Arturo Alvarez-Buylla
Arturo Alvarez-Buylla University of California, San Francisco
Stephen C. Noctor
Stephen C. Noctor University of California, Davis
John L.R. Rubenstein
John L.R. Rubenstein University of California, San Francisco
Verónica Martínez-Cerdeño
Verónica Martínez-Cerdeño University of California, Davis
Aviv Regev
Aviv Regev Genentech
Sarah A. Teichmann
Sarah A. Teichmann University of Cambridge
John C. Marioni
John C. Marioni European Bioinformatics Institute
Eric S. Lander
Eric S. Lander Broad Institute
Maximilian Haeussler
Maximilian Haeussler University of California, Santa Cruz
Wolf Reik
Wolf Reik Babraham Institute

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