World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
88
Citations
23164
World Ranking
13344
National Ranking
6787

Overview

John N. Lorenz is affiliated with the University of Cincinnati Medical Center in the United States. Their research spans multiple disciplines within medicine and biochemistry, genetics, and molecular biology, with a particular focus on cardiology and molecular mechanisms underlying muscle function.

The scientist's main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broader fields, their work concentrates on several subfields such as:

  • Cardiology and Cardiovascular Medicine
  • Molecular Biology
  • Genetics
  • Pathology and Forensic Medicine
  • Developmental Neuroscience

The topics covered by their publications reflect this range, including:

  • Cardiomyopathy and Myosin Studies
  • Cardiovascular Function and Risk Factors
  • Cardiovascular Effects of Exercise
  • RNA Research and Splicing
  • Muscle Physiology and Disorders
  • Neurogenetic and Muscular Disorders Research
  • Signaling Pathways in Disease

Some recent papers authored or coauthored by Lorenz are:

  • Fast skeletal myosin-binding protein-C regulates fast skeletal muscle contraction, 2021, Proceedings of the National Academy of Sciences
  • Amino terminus of cardiac myosin binding protein-C regulates cardiac contractility, 2021, Journal of Molecular and Cellular Cardiology
  • Guidelines for assessing ventricular pressure-volume relationships in rodents, 2024, American Journal of Physiology-Heart and Circulatory Physiology
  • Unlocking the Role of sMyBP-C: A Key Player in Skeletal Muscle Development and Growth, 2023, bioRxiv (Cold Spring Harbor Laboratory)
  • HuR inhibition reduces post-ischemic cardiac remodeling by dampening acute inflammatory gene expression and the innate immune response, 2023, bioRxiv (Cold Spring Harbor Laboratory)

Frequent collaborators of John N. Lorenz include:

  • Michelle L. Nieman
  • Sakthivel Sadayappan
  • James W. McNamara
  • Taejeong Song
  • Rohit Singh

Among publication venues where Lorenz often publishes are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Circulation Research
  • American Journal of Physiology-Heart and Circulatory Physiology
  • Physiology
  • Proceedings of the National Academy of Sciences

Best Publications

  • Transgenic Gαq overexpression induces cardiac contractile failure in mice

    Drew D. D’Angelo;Yoshihito Sakata;John N. Lorenz;Gregory P. Boivin

  • Renal and intestinal absorptive defects in mice lacking the NHE3 Na + /H + exchanger

    Patrick J. Schultheis;Lane L. Clarke;Pierre Meneton;Marian L. Miller

  • PKC-alpha regulates cardiac contractility and propensity toward heart failure.

    Julian C Braz;Kimberly Gregory;Anand Pathak;Wen Zhao

  • GDF15/MIC-1 Functions As a Protective and Antihypertrophic Factor Released From the Myocardium in Association With SMAD Protein Activation

    Jian Xu;Thomas R. Kimball;John N. Lorenz;David A. Brown

  • A role for Smad6 in development and homeostasis of the cardiovascular system

    Katherine M. Galvin;Michael J. Donovan;Catherine A. Lynch;Ronald I. Meyer

  • Early and Delayed Consequences of β2-Adrenergic Receptor Overexpression in Mouse Hearts Critical Role for Expression Level

    Stephen B. Liggett;Nicole M. Tepe;John N. Lorenz;Amy M. Canning

  • Fibroblast growth factor 2 control of vascular tone.

    Ming Zhou;Roy L. Sutliff;Richard J. Paul;John N. Lorenz

  • Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy.

    Faisal Adhami;Faisal Adhami;Guanghong Liao;Yury M. Morozov;Aryn Schloemer

  • Mice Lacking the Basolateral Na-K-2Cl Cotransporter Have Impaired Epithelial Chloride Secretion and Are Profoundly Deaf

    Michael Flagella;Lane L. Clarke;Marian L. Miller;Lawrence C. Erway

  • Sustained in vivo cardiac protection by a rationally designed peptide that causes ɛ protein kinase C translocation

    Gerald W. Dorn;Miriam C. Souroujon;Miriam C. Souroujon;Tamar Liron;Che Hong Chen

  • Evolution of the mdx mouse cardiomyopathy: physiological and morphological findings.

    John G. Quinlan;Harvey S. Hahn;Brenda L. Wong;John N. Lorenz

  • Impaired Cardiac Performance in Heterozygous Mice with a Null Mutation in the Sarco(endo)plasmic Reticulum Ca2+-ATPase Isoform 2 (SERCA2) Gene

    Muthu Periasamy;Thomas D. Reed;Lynne H. Liu;Yong Ji

  • Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy.

    Martin G. Yussman;Tsuyoshi Toyokawa;Amy Odley;Roy A. Lynch

  • Impaired cardiac hypertrophic response in Calcineurin Aβ-deficient mice

    Orlando F. Bueno;Benjamin J. Wilkins;Kevin M. Tymitz;Betty J. Glascock

  • Low- and high-level transgenic expression of β2-adrenergic receptors differentially affect cardiac hypertrophy and function in Gαq-overexpressing mice

    Gerald W. Dorn;Nicole M. Tepe;John N. Lorenz;Walter J. Koch

  • Expression of R120G–αB-Crystallin Causes Aberrant Desmin and αB-Crystallin Aggregation and Cardiomyopathy in Mice

    Xuejun Wang;Hanna Osinska;Raisa Klevitsky;A. Martin Gerdes

  • Mice without myoglobin

    Daniel J. Garry;George A. Ordway;John N. Lorenz;Nina B. Radford

  • Phenotype Resembling Gitelman's Syndrome in Mice Lacking the Apical Na+-Cl− Cotransporter of the Distal Convoluted Tubule *

    Patrick J. Schultheis;John N. Lorenz;Pierre Meneton;Michelle L. Nieman

  • Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins

    Mary Donoghue;Hiroko Wakimoto;Colin T Maguire;Susan Acton

  • MEK1-ERK2 Signaling Pathway Protects Myocardium From Ischemic Injury In Vivo

    Daniel J. Lips;Orlando F. Bueno;Benjamin J. Wilkins;Nicole H. Purcell

Frequent Co-Authors

Gary E. Shull
Gary E. Shull University of Cincinnati Medical Center
Jeffrey Robbins
Jeffrey Robbins Cincinnati Children's Hospital Medical Center
Jeffery D. Molkentin
Jeffery D. Molkentin Cincinnati Children's Hospital Medical Center
Jerry B. Lingrel
Jerry B. Lingrel University of Cincinnati
Evangelia G. Kranias
Evangelia G. Kranias University of Cincinnati Medical Center
Thomas Doetschman
Thomas Doetschman University of Arizona
Stephen B. Liggett
Stephen B. Liggett University of South Florida
Yigang Wang
Yigang Wang University of Cincinnati
Gregory P. Boivin
Gregory P. Boivin Wright State University
Jurgen Schnermann
Jurgen Schnermann National Institutes of Health

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