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Howard A. Rockman

Howard A. Rockman

D-Index & Metrics

Medicine

D-Index
93
Citations
31068
World Ranking
10910
National Ranking
5611

Research.com Recognitions

  • 2015 - Distinguished Scientist Award, American Heart Association
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Howard A. Rockman is affiliated with Duke University in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Cardiology and Cardiovascular Medicine, Cellular and Molecular Neuroscience, Animal Science and Zoology, and Public Health, Environmental and Occupational Health.

The scientist's main topics of work include Receptor Mechanisms and Signaling, Neuropeptides and Animal Physiology, Pharmacological Effects and Assays, Cardiac Electrophysiology and Arrhythmias, Computational Drug Discovery Methods, Monoclonal and Polyclonal Antibodies Research, and Renin-Angiotensin System Studies.

Recent notable publications by Howard A. Rockman include:

  • G Protein-Coupled Receptors: A Century of Research and Discovery (2024), published in Circulation Research
  • G protein-coupled receptor signaling: transducers and effectors (2022), published in American Journal of Physiology-Cell Physiology
  • Synthetic nanobodies as angiotensin receptor blockers (2020), published in Proceedings of the National Academy of Sciences
  • The β-arrestin-biased β-adrenergic receptor blocker carvedilol enhances skeletal muscle contractility (2020), published in Proceedings of the National Academy of Sciences
  • β-Arrestin-Biased Allosteric Modulator Potentiates Carvedilol-Stimulated β Adrenergic Receptor Cardioprotection (2021), published in Molecular Pharmacology

Key frequent co-authors of Rockman include Robert J. Lefkowitz, Haoran Jiang, Lan Mao, Seungkirl Ahn, and Jialu Wang.

Their work has appeared in various publication venues such as UNC Libraries, Circulation Research, bioRxiv (Cold Spring Harbor Laboratory), Proceedings of the National Academy of Sciences, and Circulation.

Awards and honors received include the Distinguished Scientist Award from the American Heart Association in 2015 and membership in the Association of American Physicians.

Best Publications

  • Seven-transmembrane-spanning receptors and heart function

    Howard A. Rockman;Walter J. Koch;Robert J. Lefkowitz

  • Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy

    Howard A. Rockman;Robert S. Ross;Adrienne N. Harris;Kirk U. Knowlton

  • Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor

    C. A. Milano;L. F. Allen;H. A. Rockman;P. C. Dolber

  • Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor.

    Walter J. Koch;Howard A. Rockman;Philippe Samama;RaeAnn Hamilton

  • Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A

    Paula M. Oliver;Jennifer E. Fox;Ron Kim;Howard A. Rockman

  • Expression of a β-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice

    Howard A. Rockman;Kenneth R. Chien;D. O. N. G. . J. U. Choi;Guido Iaccarino

  • Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy.

    Shahab A. Akhter;Louis M. Luttrell;Howard A. Rockman;Guido Iaccarino

  • Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β2-adrenoceptor

    R A Bond;P Leff;T D Johnson;C A Milano

  • β-Arrestin–mediated β1-adrenergic receptor transactivation of the EGFR confers cardioprotection

    Takahisa Noma;Anthony Lemaire;Sathyamangla V. Naga Prasad;Liza Barki-Harrington;Liza Barki-Harrington

  • Genetic Alterations That Inhibit In Vivo Pressure-Overload Hypertrophy Prevent Cardiac Dysfunction Despite Increased Wall Stress

    Giovanni Esposito;Antonio Rapacciuolo;Sathyamangla V. Naga Prasad;Hideyuki Takaoka

  • Transthoracic echocardiography in models of cardiac disease in the mouse

    Nobuaki Tanaka;Nancy Dalton;Lan Mao;Howard A. Rockman

  • Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy.

    Carmelo A. Milano;Paul C. Dolber;Howard A. Rockman;Richard A. Bond

  • Animal Models of Heart Failure A Scientific Statement From the American Heart Association

    Steven R. Houser;Kenneth B. Margulies;Anne M. Murphy;Francis G. Spinale

  • Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function.

    Mohamed Jaber;Walter J. Koch;Howard Rockman;Bradley Smith

  • Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I

    Vishram Kedar;Holly McDonough;Ranjana Arya;Hui Hua Li

  • Overexpression of the rat sarcoplasmic reticulum Ca2+ ATPase gene in the heart of transgenic mice accelerates calcium transients and cardiac relaxation

    H He;F J Giordano;R Hilal-Dandan;D J Choi

  • Ventricular Expression of a MLC-2v-ras Fusion Gene Induces Cardiac Hypertrophy and Selective Diastolic Dysfunction in Transgenic Mice

    John J. Hunter;Nobuaki Tanaka;Howard A. Rockman;John Ross

  • Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice

    Susan B. Gurley;Alicia Allred;Thu H. Le;Robert Griffiths

  • Cardiac βARK1 inhibition prolongs survival and augments β blocker therapy in a mouse model of severe heart failure

    Victoria B. Harding;Larry R. Jones;Robert J. Lefkowitz;Walter J. Koch

  • Corrections and Retraction: Segregation of Atrial-Specific and Inducible Expression of an Atrial Natriuretic Factor Transgene in an In vivo Murine Model of Cardiac Hypertrophy

    Howard A. Rockman;Robert S. Ross;Adrienne N. Harris;Kirk U. Knowlton

Frequent Co-Authors

Robert J. Lefkowitz
Robert J. Lefkowitz Duke University
Walter J. Koch
Walter J. Koch Temple University
John Ross
John Ross University of California, San Diego
Douglas A. Marchuk
Douglas A. Marchuk Duke University
Carmelo A. Milano
Carmelo A. Milano Duke University
Kenneth R. Chien
Kenneth R. Chien Karolinska Institute
Louis M. Luttrell
Louis M. Luttrell Medical University of South Carolina
Marc G. Caron
Marc G. Caron Duke University
John Ross
John Ross University of Tasmania
Sudha K. Shenoy
Sudha K. Shenoy Duke University

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