2015 - Distinguished Scientist Award, American Heart Association
Member of the Association of American Physicians
The scientist’s investigation covers issues in Endocrinology, Internal medicine, Receptor, Muscle hypertrophy and Pressure overload. His work carried out in the field of Endocrinology brings together such families of science as Cardiac function curve, Heart failure and Transgene. Internal medicine is closely attributed to Cardiology in his study.
The concepts of his Receptor study are interwoven with issues in Inotrope and Signal transduction, Cell biology. He usually deals with Muscle hypertrophy and limits it to topics linked to Genetically modified mouse and Heart disease, Alpha-1B adrenergic receptor, Diacylglycerol kinase and Alpha. His Pressure overload study integrates concerns from other disciplines, such as Ovarian hormone, Circulatory system, Gene expression and Atrial natriuretic peptide.
His scientific interests lie mostly in Internal medicine, Endocrinology, Receptor, Heart failure and Cell biology. He works mostly in the field of Internal medicine, limiting it down to concerns involving Cardiology and, occasionally, Diastole and Blood pressure. His Endocrinology research includes themes of Genetically modified mouse, Transgene, Beta adrenergic receptor kinase, Kinase and In vivo.
In his study, which falls under the umbrella issue of Receptor, Neuroscience and Pharmacology is strongly linked to Signal transduction. His studies in Heart failure integrate themes in fields like Inotrope, Heart disease and Disease. Howard A. Rockman interconnects Internalization and Transactivation in the investigation of issues within Cell biology.
Howard A. Rockman focuses on Receptor, Cell biology, Internal medicine, Arrestin and G protein-coupled receptor. His research integrates issues of Signal transduction, Pharmacology, Phosphorylation and Effector in his study of Receptor. His Cell biology research integrates issues from Angiotensin II and microRNA.
His Internal medicine study incorporates themes from Endocrinology and Cardiology. He has included themes like Cardiac function curve and Beta-Arrestins in his Endocrinology study. His study in G protein-coupled receptor is interdisciplinary in nature, drawing from both G protein, Cell surface receptor, Neuroscience, Binding site and Drug discovery.
Cell biology, Receptor, Angiotensin II, Heart failure and G protein are his primary areas of study. Howard A. Rockman works mostly in the field of Cell biology, limiting it down to topics relating to Molecular biology and, in certain cases, Effector, Second messenger system, Dicer, microRNA and Gene expression. He regularly links together related areas like Pressure overload in his Receptor studies.
His Angiotensin II research is multidisciplinary, relying on both Arrestin and Cell signaling. His Heart failure research includes elements of Endocrinology and Pathological. The various areas that Howard A. Rockman examines in his G protein study include G protein-coupled receptor and Signal transducing adaptor protein.
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Seven-transmembrane-spanning receptors and heart function
Howard A. Rockman;Walter J. Koch;Robert J. Lefkowitz.
Nature (2002)
Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy
Howard A. Rockman;Robert S. Ross;Adrienne N. Harris;Kirk U. Knowlton.
Proceedings of the National Academy of Sciences of the United States of America (1991)
Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor
CA Milano;LF Allen;HA Rockman;PC Dolber.
Science (1994)
Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor.
WJ Koch;HA Rockman;P Samama;RA Hamilton.
Science (1995)
Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A
Paula M. Oliver;Jennifer E. Fox;Ron Kim;Howard A. Rockman.
Proceedings of the National Academy of Sciences of the United States of America (1997)
Expression of a β-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice
Howard A. Rockman;Kenneth R. Chien;D. O. N. G. . J. U. Choi;Guido Iaccarino.
Proceedings of the National Academy of Sciences of the United States of America (1998)
Targeting the Receptor-Gq Interface to Inhibit in Vivo Pressure Overload Myocardial Hypertrophy
Shahab A. Akhter;Louis M. Luttrell;Howard A. Rockman;Guido Iaccarino.
Science (1998)
Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β2-adrenoceptor
Richard A. Bond;Paul Leff;T.David Johnson;Carmelo A. Milano.
Nature (1995)
Genetic Alterations That Inhibit In Vivo Pressure-Overload Hypertrophy Prevent Cardiac Dysfunction Despite Increased Wall Stress
Giovanni Esposito;Antonio Rapacciuolo;Sathyamangla V. Naga Prasad;Hideyuki Takaoka.
Circulation (2002)
β-Arrestin–mediated β1-adrenergic receptor transactivation of the EGFR confers cardioprotection
Takahisa Noma;Anthony Lemaire;Sathyamangla V. Naga Prasad;Liza Barki-Harrington;Liza Barki-Harrington.
Journal of Clinical Investigation (2007)
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